Company profile for MiNK Therapeutics

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About

MiNK Therapeutics is a clinical-stage precision oncology company developing allogeneic, invariant natural killer T cell therapies for cancer and other immune-mediated diseases. The lead product is an off-the-shelf, cell therapy based on a targeted platform of invariant natural killer T (iNKT) cells. iNKTs have a dual-mechanism of action with an internal targeting and homing device (iTCR) that modulates both arms of immunity, i...
MiNK Therapeutics is a clinical-stage precision oncology company developing allogeneic, invariant natural killer T cell therapies for cancer and other immune-mediated diseases. The lead product is an off-the-shelf, cell therapy based on a targeted platform of invariant natural killer T (iNKT) cells. iNKTs have a dual-mechanism of action with an internal targeting and homing device (iTCR) that modulates both arms of immunity, innate and adaptive. iNKTs combine the killing features of natural killer (NK) cells with the durable memory response of T cells.

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CONTACT DETAILS

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Country
Country
U.S.A
Address
Address
149 Fifth Avenue Suite 500 New York, NY 10010
Telephone
Telephone
212.994.8250
youtube
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NEWS #PharmaBuzz

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https://www.globenewswire.com/news-release/2026/04/03/3267986/0/en/MiNK-Therapeutics-and-Memorial-Sloan-Kettering-to-Present-Phase-II-Study-of-agenT-797-Combination-in-PD-1-Refractory-Gastroesophageal-Cancer-at-AACR-2026.html

GLOBENEWSWIRE
03 Apr 2026

https://www.globenewswire.com/news-release/2026/03/31/3265350/0/en/MiNK-Therapeutics-Reports-Q4-and-Full-Year-2025-Results-Phase-2-Programs-Advance-with-Impactful-Non-Dilutive-Momentum.html

GLOBENEWSWIRE
31 Mar 2026

https://www.globenewswire.com/news-release/2026/03/17/3257040/0/en/MiNK-Therapeutics-to-Report-Fourth-Quarter-and-Full-Year-2025-Financial-Results-and-Highlight-Platform-Expansion-Across-iNKT-Cell-Therapy-Programs.html

GLOBENEWSWIRE
17 Mar 2026

https://www.globenewswire.com/news-release/2026/03/10/3252525/0/en/MiNK-Therapeutics-Announces-Collaboration-with-C-Further-to-Advance-PRAME-Targeted-iNKT-Cell-Therapy-for-Pediatric-Cancers.html

GLOBENEWSWIRE
10 Mar 2026

https://www.pharmiweb.com/press-release/2026-03-10/c-further-unveils-first-therapeutic-programmes-dedicated-to-paediatric-oncology

PHARMIWEB
10 Mar 2026

https://www.globenewswire.com/news-release/2026/01/08/3215679/0/en/MiNK-Therapeutics-and-University-of-Wisconsin-Madison-Announce-Phase-1-Clinical-Trial-of-Allo-iNKT-Cell-Therapy-AgenT-797-to-Evaluate-Prevention-of-Graft-Versus-Host-Disease.html

GLOBENEWSWIRE
08 Jan 2026

Drugs in Development

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Details:

The collaboration aims to develop a novel cell & gene therapy targeting PRAME for sarcoma treatment.


Lead Product(s): Undisclosed

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: PreclinicalProduct Type: Cell & Gene Therapy

Sponsor: C-Further

Deal Size: $1.1 million Upfront Cash: Undisclosed

Deal Type: Collaboration March 10, 2026

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Lead Product(s) : Undisclosed

Therapeutic Area : Oncology

Highest Development Status : Preclinical

Partner/Sponsor/Collaborator : C-Further

Deal Size : $1.1 million

Deal Type : Collaboration

Details : The collaboration aims to develop a novel cell & gene therapy targeting PRAME for sarcoma treatment.

Product Name : Undisclosed

Product Type : Cell & Gene Therapy

Upfront Cash : Undisclosed

March 10, 2026

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Details:

AgenT-797, a cell & gene therapy, shows promise in treating Graft-versus-host Disease (GVHD).


Lead Product(s): AgenT-797

Therapeutic Area: Immunology Brand Name: Undisclosed

Study Phase: IND EnablingProduct Type: Cell & Gene Therapy

Sponsor: National Institute of Allergy and Infectious Diseases

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable January 08, 2026

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Sampe
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Sampe
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Details : AgenT-797, a cell & gene therapy, shows promise in treating Graft-versus-host Disease (GVHD).

Product Name : Undisclosed

Product Type : Cell & Gene Therapy

Upfront Cash : Inapplicable

January 08, 2026

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Details:

MiNK-215, a cell & gene therapy targeting FAP-expressing CAF, shows promise in treating lung cancer.


Lead Product(s): MiNK-215

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: PreclinicalProduct Type: Cell & Gene Therapy

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable November 20, 2025

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Details : MiNK-215, a cell & gene therapy targeting FAP-expressing CAF, shows promise in treating lung cancer.

Product Name : Undisclosed

Product Type : Cell & Gene Therapy

Upfront Cash : Inapplicable

November 20, 2025

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Details:

The grant will support development of MiNK’s allo-iNKT cell therapy, AGENT-797, for the prevention and treatment of graft-versus-host disease (GvHD) following hematopoietic stem cell transplantation.


Lead Product(s): AGENT-797

Therapeutic Area: Immunology Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Cell & Gene Therapy

Sponsor: National Institute of Allergy and Infectious Diseases

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Funding June 02, 2025

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Details : The grant will support development of MiNK’s allo-iNKT cell therapy, AGENT-797, for the prevention and treatment of graft-versus-host disease (GvHD) following hematopoietic stem cell transplantation.

Product Name : Undisclosed

Product Type : Cell & Gene Therapy

Upfront Cash : Undisclosed

June 02, 2025

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Details:

The collaboration will leverage Autonomous’ precision encRNA technology and MiNK’s innovative iNKT cell therapies, MiNK-215, an investigational, off-the-shelf cellular immunotherapy, and agenT-797.


Lead Product(s): MiNK-215

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: PreclinicalProduct Type: Cell & Gene Therapy

Recipient: Autonomous Therapeutics

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration October 08, 2024

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Details : The collaboration will leverage Autonomous’ precision encRNA technology and MiNK’s innovative iNKT cell therapies, MiNK-215, an investigational, off-the-shelf cellular immunotherapy, and agenT-797.

Product Name : Undisclosed

Product Type : Cell & Gene Therapy

Upfront Cash : Undisclosed

October 08, 2024

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Details:

The net proceeds will advance the clinical development of MiNK-215, a novel cell therapeutic and allogeneic CAR-iNKT cell therapy targeting fibroblast activation protein (FAP) in solid tumors.


Lead Product(s): MiNK-215

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: PreclinicalProduct Type: Cell & Gene Therapy

Sponsor: GKCC

Deal Size: $5.8 million Upfront Cash: Undisclosed

Deal Type: Private Placement May 13, 2024

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Sampe
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Details : The net proceeds will advance the clinical development of MiNK-215, a novel cell therapeutic and allogeneic CAR-iNKT cell therapy targeting fibroblast activation protein (FAP) in solid tumors.

Product Name : Undisclosed

Product Type : Cell & Gene Therapy

Upfront Cash : Undisclosed

May 13, 2024

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Details:

MiNK-215 is an investigational IL-15 armored FAP-targeting CAR-iNKT cell therapy being studied in the preclinical stage as a novel approach for patients with colorectal cancer liver metastases.


Lead Product(s): MiNK-215

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: PreclinicalProduct Type: Cell & Gene Therapy

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable March 06, 2024

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Details : MiNK-215 is an investigational IL-15 armored FAP-targeting CAR-iNKT cell therapy being studied in the preclinical stage as a novel approach for patients with colorectal cancer liver metastases.

Product Name : Undisclosed

Product Type : Cell & Gene Therapy

Upfront Cash : Inapplicable

March 06, 2024

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Details:

AgenT-797 is composed of allogeneic iNKT cells being evaluated with botensilimab and balstilimab for gastroesophageal cancer treatment.


Lead Product(s): AgenT-797,Balstilimab,Botensilimab

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IIProduct Type: Cell & Gene Therapy

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable February 14, 2024

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Not Confirmed
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Lead Product(s) : AgenT-797,Balstilimab,Botensilimab

Therapeutic Area : Oncology

Highest Development Status : Phase II

Partner/Sponsor/Collaborator : Undisclosed

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : AgenT-797 is composed of allogeneic iNKT cells being evaluated with botensilimab and balstilimab for gastroesophageal cancer treatment.

Product Name : Undisclosed

Product Type : Cell & Gene Therapy

Upfront Cash : Inapplicable

February 14, 2024

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Details:

MiNK-413, a next generation armored allogenic BCMA-CAR-iNKT product effectively eliminated MM cells in a CAR-dependent manner, without losing their T cell receptor (TCR)-mediated cytotoxic activity.


Lead Product(s): MiNK-413

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: IND EnablingProduct Type: Cell & Gene Therapy

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable October 05, 2022

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Sampe
Not Confirmed
Sampe
Not Confirmed

Details : MiNK-413, a next generation armored allogenic BCMA-CAR-iNKT product effectively eliminated MM cells in a CAR-dependent manner, without losing their T cell receptor (TCR)-mediated cytotoxic activity.

Product Name : Undisclosed

Product Type : Cell & Gene Therapy

Upfront Cash : Inapplicable

October 05, 2022

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Details:

Clinical data show AgenT-797, an unmodified, allogeneic iNKT cell therapy can be dosed to 1 billion cells without lymphodepletion, with no evidence of cytokine release syndrome or neurotoxicity in Solid Tumor Cancers.


Lead Product(s): AgenT-797,Nivolumab

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Cell & Gene Therapy

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable March 03, 2022

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Sampe
Not Confirmed
Sampe
Not Confirmed

Details : Clinical data show AgenT-797, an unmodified, allogeneic iNKT cell therapy can be dosed to 1 billion cells without lymphodepletion, with no evidence of cytokine release syndrome or neurotoxicity in Solid Tumor Cancers.

Product Name : Undisclosed

Product Type : Cell & Gene Therapy

Upfront Cash : Inapplicable

March 03, 2022

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