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              Horizon Therapeutics

              • Development Update

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              IRELAND Ireland

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              CPhI Japan 2021

              Participation Not Confirmed

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              Higher Response Rates in RECIPE Randomized Controlled Trial of KRYSTEXXA® Concomitantly Used with the Immunomodulator Mycophenolate Mofetil

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              Lead Product(s): Pegloticase,Mycophenolate Mofetil

              Therapeutic Area: Musculoskeletal Product Name: Krystexxa

              Highest Development Status: Phase II Product Type: Large molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable November 02, 2020

              Details:

              Reducing Immunogenicity of Pegloticase demonstrated that 86.4 percent of patients receiving co-therapy of KRYSTEXXA with the immunomodulator mycophenolate mofetil achieved serum uric acid (sUA) ≤ 6 mg/dL through Month 3, the primary endpoint of the study.

              Horizon Therapeutics

              • Development Update

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              IRELAND Ireland

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              Virtual Booth Virtual Booth

              CPhI Japan 2021

              Participation Not Confirmed

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              New Data Evaluating KRYSTEXXA® With Concomitant Immunomodulation to Be Presented at the American College of Rheumatology Convergence 2020

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              Lead Product(s): Pegloticase,Mycophenolate Mofetil

              Therapeutic Area: Musculoskeletal Product Name: Krystexxa

              Highest Development Status: Phase II Product Type: Large molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable October 08, 2020

              Details:

              Additional studies on the concomitant use of KRYSTEXXA (pegloticase injection) with an immunomodulator to optimize the treatment for people living with chronic gout refractory to conventional therapies (also known as uncontrolled gout) will also be presented.

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