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Inapplicable","highestDevelopmentStatusID":"11","companyTruncated":"Laboratoires des M\u00e9dicaments St\u00e9riles \/ Inapplicable"},{"orgOrder":0,"company":"Biocodex","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Dermatology","country":"FRANCE","productType":"Antibiotic","year":"2024","type":"Inapplicable","leadProduct":"Amoxicillin Trihydrate","moa":"||Bacterial penicillin-binding protein","graph1":"Dermatology","graph2":"Phase IV","graph3":"Biocodex","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Biocodex \/ Inapplicable","highestDevelopmentStatusID":"11","companyTruncated":"Biocodex \/ Inapplicable"},{"orgOrder":0,"company":"Sunnybrook Health Sciences Centre","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"","productType":"Antibiotic","year":"2020","type":"Inapplicable","leadProduct":"Amoxicillin Trihydrate","moa":"||Bacterial penicillin-binding protein","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase III","graph3":"Sunnybrook Health Sciences Centre","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Sunnybrook Health Sciences Centre \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Sunnybrook Health Sciences Centre \/ Inapplicable"},{"orgOrder":0,"company":"Aga Khan University","sponsor":"Searle Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Vonoprazan Fumarate","moa":"||Potassium-transporting ATPase","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Aga Khan University","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Aga Khan University \/ Searle Pharmaceuticals","highestDevelopmentStatusID":"10","companyTruncated":"Aga Khan University \/ Searle Pharmaceuticals"},{"orgOrder":0,"company":"Kaizen Bioscience","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Otolaryngology (Ear, Nose, Throat)","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Amoxicillin Trihydrate","moa":"||K-ATPase","graph1":"Otolaryngology (Ear, Nose, Throat)","graph2":"Phase III","graph3":"Kaizen Bioscience","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Otolaryngology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Kaizen Bioscience \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Kaizen Bioscience \/ Inapplicable"},{"orgOrder":0,"company":"Fundacion Agencia Aragonesa para la Investigacion y Desarrollo","sponsor":"Universidad de Zaragoza | Fondation Raoul Follereau | Universit\u00e9 d'Abomey-Calavi | Instituto de Salud Carlos III | Fundaci\u00f3n Anesvad | Tres Cantos Open Lab Foundation | GSK","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Antibiotic","year":"2021","type":"Inapplicable","leadProduct":"Rifampicin","moa":"||Bacterial DNA-directed RNA polymerase","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Fundacion Agencia Aragonesa para la Investigacion y Desarrollo","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Fundacion Agencia Aragonesa para la Investigacion y Desarrollo \/ Universidad de Zaragoza | Fondation Raoul Follereau | Universit\u00e9 d'Abomey-Calavi | Instituto de Salud Carlos III | Fundaci\u00f3n Anesvad | Tres Cantos Open Lab Foundation | GSK","highestDevelopmentStatusID":"8","companyTruncated":"Fundacion Agencia Aragonesa para la Investigacion y Desarrollo \/ Universidad de Zaragoza | Fondation Raoul Follereau | Universit\u00e9 d'Abomey-Calavi | Instituto de Salud Carlos III | Fundaci\u00f3n Anesvad | Tres Cantos Open Lab Foundation | GSK"},{"orgOrder":0,"company":"Western Sydney Local Health District","sponsor":"Centre Of Research Excellence in Tuberculosis Control","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Cephalexin","moa":"||Bacterial penicillin-binding protein","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"Western Sydney Local Health District","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Western Sydney Local Health District \/ Centre Of Research Excellence in Tuberculosis Control","highestDevelopmentStatusID":"8","companyTruncated":"Western Sydney Local Health District \/ Centre Of Research Excellence in Tuberculosis Control"},{"orgOrder":0,"company":"Takeda Pharmaceutical","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"JAPAN","productType":"Antibiotic","year":"2021","type":"Inapplicable","leadProduct":"Clarithromycin","moa":"||Bacterial 70S ribosome","graph1":"Undisclosed","graph2":"Phase I","graph3":"Takeda Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Takeda Pharmaceutical \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Takeda Pharmaceutical \/ Inapplicable"},{"orgOrder":0,"company":"Kaizen Bioscience","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Antibiotic","year":"2022","type":"Inapplicable","leadProduct":"Amoxicillin Trihydrate","moa":"||Bacterial penicillin-binding protein","graph1":"Infections and Infectious Diseases","graph2":"Phase I","graph3":"Kaizen Bioscience","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Kaizen Bioscience \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Kaizen Bioscience \/ Inapplicable"},{"orgOrder":0,"company":"Sihuan Pharmaceutical","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"CHINA","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Amoxicillin","moa":"||K-ATPase","graph1":"Undisclosed","graph2":"Phase I","graph3":"Sihuan Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Sihuan Pharmaceutical \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Sihuan Pharmaceutical \/ Inapplicable"},{"orgOrder":0,"company":"Washington University School of Medicine","sponsor":"Project Peanut Butter | Ministry of Health and Sanitation, Sierra Leone | Arla Foods Ingredients | The Danish Dairy Research Foundation, Denmark","pharmaFlowCategory":"DU","therapeuticArea":"Nutrition and Weight Loss","country":"U.S.A","productType":"Dietary Supplement","year":"2025","type":"Inapplicable","leadProduct":"Amoxicillin","moa":"||Undisclosed","graph1":"Nutrition and Weight Loss","graph2":"Undisclosed","graph3":"Washington University School of Medicine","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Nutrition & Weight Loss","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Washington University School of Medicine \/ Project Peanut Butter | Ministry of Health and Sanitation, Sierra Leone | Arla Foods Ingredients | The Danish Dairy Research Foundation, Denmark","highestDevelopmentStatusID":"1","companyTruncated":"Washington University School of Medicine \/ Project Peanut Butter | Ministry of Health and Sanitation, Sierra Leone | Arla Foods Ingredients | The Danish Dairy Research Foundation, Denmark"},{"orgOrder":0,"company":"Slovenian Society for Gastroenterology and Hepatology","sponsor":"Krka","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Esomeprazole Magnesium","moa":"||Potassium-transporting ATPase","graph1":"Infections and Infectious Diseases","graph2":"Undisclosed","graph3":"Slovenian Society for Gastroenterology and Hepatology","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Slovenian Society for Gastroenterology and Hepatology \/ Krka","highestDevelopmentStatusID":"1","companyTruncated":"Slovenian Society for Gastroenterology and Hepatology \/ Krka"},{"orgOrder":0,"company":"University of Guarulhos","sponsor":"ITI Foundation","pharmaFlowCategory":"DU","therapeuticArea":"Dental and Oral Health","country":"","productType":"Plant Extract\/Herbal","year":"2022","type":"Inapplicable","leadProduct":"Metronidazole","moa":"||DNA","graph1":"Dental and Oral Health","graph2":"Undisclosed","graph3":"University of Guarulhos","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dental & Oral Health","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"University of Guarulhos \/ ITI Foundation","highestDevelopmentStatusID":"1","companyTruncated":"University of Guarulhos \/ ITI Foundation"},{"orgOrder":0,"company":"Anabio R&D","sponsor":"Thai Binh University of Medicine and Pharmacy","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"","productType":"Probiotic","year":"2023","type":"Inapplicable","leadProduct":"Bacillus Subtilis","moa":"||Bacteria microbiome","graph1":"Infections and Infectious Diseases","graph2":"Undisclosed","graph3":"Anabio R&D","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Anabio R&D \/ Thai Binh University of Medicine and Pharmacy","highestDevelopmentStatusID":"1","companyTruncated":"Anabio R&D \/ Thai Binh University of Medicine and Pharmacy"},{"orgOrder":0,"company":"Key Laboratory for Gastrointestinal Diseases","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"","productType":"Undisclosed","year":"2025","type":"Inapplicable","leadProduct":"Amoxicillin","moa":"||Undisclosed","graph1":"Undisclosed","graph2":"Undisclosed","graph3":"Key Laboratory for Gastrointestinal Diseases","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Key Laboratory for Gastrointestinal Diseases \/ Inapplicable","highestDevelopmentStatusID":"1","companyTruncated":"Key Laboratory for Gastrointestinal Diseases \/ Inapplicable"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          Details : Vonoprazan is a novel potassium-competitive acid blocker (PCAB). It inhibits gastric acid secretion by acting as a reversible competitive inhibitor against potassium ions.

                          Product Name : Voquezna Triple Pack

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          October 24, 2022

                          Lead Product(s) : Vonoprazan Fumarate,Amoxicillin Trihydrate,Clarithromycin

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : Phathom Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Agreement

                          Evonik company banner

                          02

                          London School of Hygiene & Tropical Medicine

                          Country arrow
                          EPSC
                          Not Confirmed

                          London School of Hygiene & Tropical Medicine

                          Country arrow
                          EPSC
                          Not Confirmed

                          Lead Product(s) : Linezolid,Amoxicillin Trihydrate

                          Therapeutic Area : Infections and Infectious Diseases

                          Study Phase : Phase II

                          Sponsor : University College Dublin | University of Stellenbosch | Malawi Liverpool Wellcome Programme | University of Sydney | Murdoch Childrens Research Institute | MRC CTU at UCL | PHPT/AMS Laboratory

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          April 10, 2025

                          Lead Product(s) : Linezolid,Amoxicillin Trihydrate

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : University College Dublin | University of Stellenbosch | Malawi Liverpool Wellcome Programme | University of Sydney | Murdoch Childrens Research Institute | MRC CTU at UCL | PHPT/AMS Laboratory

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Talicia is a novel, fixed-dose combination of two antibiotics (amoxicillin and rifabutin) and a proton pump inhibitor (omeprazole), approved by the U.S. FDA for the treatment of H. pylori infection.

                          Product Name : Talicia

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          March 18, 2025

                          Lead Product(s) : Omeprazole Magnesium,Amoxicillin Trihydrate,Rifabutin

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Lead Product(s) : MFGM-RUTF,Amoxicillin Trihydrate,Sulfadoxine,Pyrimethamine,Artemether+Lumefantrine

                          Therapeutic Area : Nutrition and Weight Loss

                          Study Phase : Undisclosed

                          Sponsor : Project Peanut Butter | Ministry of Health and Sanitation, Sierra Leone | Arla Foods Ingredients | The Danish Dairy Research Foundation, Denmark

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Dietary Supplement

                          Upfront Cash : Inapplicable

                          March 11, 2025

                          Lead Product(s) : MFGM-RUTF,Amoxicillin Trihydrate,Sulfadoxine,Pyrimethamine,Artemether+Lumefantrine

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Undisclosed

                          Sponsor : Project Peanut Butter | Ministry of Health and Sanitation, Sierra Leone | Arla Foods Ingredients | The Danish Dairy Research Foundation, Denmark

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Key Laboratory for Gastrointestinal Diseases

                          Country arrow
                          EPSC
                          Not Confirmed

                          Key Laboratory for Gastrointestinal Diseases

                          Country arrow
                          EPSC
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          February 28, 2025

                          Lead Product(s) : Keverprazan,Amoxicillin Trihydrate

                          Therapeutic Area : Undisclosed

                          Highest Development Status : Undisclosed

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          December 27, 2024

                          Lead Product(s) : Fexuprazan,Amoxicillin Trihydrate,Clarithromycin

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : iNtherapeutics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : LP-001 (amoxicillin/clavulanate) oral suspension is currently being investigated as an effective antimicrobial for the treatment of children with acute otitis media in 3-12 moth age pediatric.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          November 14, 2024

                          Lead Product(s) : Amoxicillin Trihydrate,Clavulanic Acid

                          Therapeutic Area : Otolaryngology (Ear, Nose, Throat)

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Antibiotic

                          Upfront Cash : Inapplicable

                          June 11, 2024

                          Lead Product(s) : Amoxicillin Trihydrate,Saccharomyces Boulardii

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase IV

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          February 26, 2024

                          Lead Product(s) : Lu AF28996,Aspirin,Mefenamic Acid,Amoxicillin Trihydrate,Clavulanic Acid

                          Therapeutic Area : Undisclosed

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Lead Product(s) : Amoxicillin Trihydrate,Inapplicable

                          Therapeutic Area : Nutrition and Weight Loss

                          Study Phase : Undisclosed

                          Sponsor : Project Peanut Butter | Kamuzu University of Health Sciences | BALCHEM

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Antibiotic

                          Upfront Cash : Inapplicable

                          December 04, 2023

                          Lead Product(s) : Amoxicillin Trihydrate,Inapplicable

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Undisclosed

                          Sponsor : Project Peanut Butter | Kamuzu University of Health Sciences | BALCHEM

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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