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    [{"orgOrder":0,"company":"HRA Pharma","sponsor":"Esteve Healthcare","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"FRANCE","productType":"Steroid","year":"2024","type":"Divestment","leadProduct":"Metyrapone","moa":"CYP11B1","graph1":"Endocrinology","graph2":"Approved FDF","graph3":"HRA Pharma","amount2":0.28999999999999998,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Endocrinology","amount2New":0.28999999999999998,"dosageForm":"Softgel Capsule","sponsorNew":"HRA Pharma \/ Esteve Healthcare","highestDevelopmentStatusID":"15","companyTruncated":"HRA Pharma \/ Esteve Healthcare"},{"orgOrder":0,"company":"Embera NeuroTherapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Steroid","year":"2020","type":"Inapplicable","leadProduct":"Metyrapone","moa":"||CYP11B1","graph1":"Psychiatry\/Psychology","graph2":"Phase II","graph3":"Embera NeuroTherapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Embera NeuroTherapeutics \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Embera NeuroTherapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Mayo Clinic","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Steroid","year":"2025","type":"Inapplicable","leadProduct":"Metyrapone","moa":"CYP11B1","graph1":"Undisclosed","graph2":"Phase II","graph3":"Mayo Clinic","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Mayo Clinic \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Mayo Clinic \/ Undisclosed"}]

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    Metyrapone

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                            01

                            Mayo Clinic

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                            Mayo Clinic

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                            Lead Product(s) : Metyrapone

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Metyrapone Study for Patients Diagnosed with Mild Autonomous Cortisol Secretion - MACS

                            Details : Metyrapone is a Steroid drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of unspecified medical condition.

                            Product Name : Undisclosed

                            Product Type : Steroid

                            Upfront Cash : Inapplicable

                            August 22, 2025

                            Lead Product(s) : Metyrapone

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            HRA Pharma

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                            HRA Pharma

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                            Lead Product(s) : Metyrapone

                            Therapeutic Area : Endocrinology

                            Study Phase : Approved FDF

                            Sponsor : Esteve Healthcare

                            Deal Size : $294.2 million

                            Deal Type : Divestment

                            DEALS_DEV arrow-down

                            Perrigo Receives Offer To Divest HRA Pharma Rare Diseases Business

                            Details : Esteve expands its rare disease portfolio through divestment, including Metopirone (metyrapone) for treating symptoms of Cushing's syndrome by lowering cortisol levels.

                            Product Name : Metopirone

                            Product Type : Steroid

                            Upfront Cash : $203.3 million

                            April 25, 2024

                            Lead Product(s) : Metyrapone

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Approved FDF

                            Sponsor : Esteve Healthcare

                            Deal Size : $294.2 million

                            Deal Type : Divestment

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                            03

                            Embera NeuroTherapeutics

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                            Embera NeuroTherapeutics

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                            Lead Product(s) : Metyrapone,Oxazepam

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Embera NeuroTherapeutics Announces First Subject Dosed in Phase 2 Study of EMB-001 in Cocaine Use Disorder

                            Details : The randomized, double-blind, placebo-controlled Phase 2 clinical trial is supported by funding from the National Institute on Drug Abuse (NIDA) of the National Institutes of Health and will evaluate EMB-001 as a treatment option for patients with cocain...

                            Product Name : Undisclosed

                            Product Type : Steroid

                            Upfront Cash : Inapplicable

                            August 31, 2020

                            Lead Product(s) : Metyrapone,Oxazepam

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Embera NeuroTherapeutics

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                            Embera NeuroTherapeutics

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                            Lead Product(s) : Metyrapone

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Phase I

                            Sponsor : National Institute on Drug Abuse

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Single and Multiple Rising Dose Study of Safety and PK of Metyrapone/Oxazepam Combination (EMB-001)

                            Details : Metyrapone is a Steroid drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Cocaine-Related Disorders.

                            Product Name : Undisclosed

                            Product Type : Steroid

                            Upfront Cash : Inapplicable

                            April 02, 2015

                            Lead Product(s) : Metyrapone

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Phase I

                            Sponsor : National Institute on Drug Abuse

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            HRA Pharma

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                            HRA Pharma

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                            Lead Product(s) : Metyrapone

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Effects of Metyrapone in Patients With Endogenous Cushing's Syndrome

                            Details : Metyrapone is a Steroid drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Cushing Syndrome.

                            Product Name : Undisclosed

                            Product Type : Steroid

                            Upfront Cash : Inapplicable

                            November 21, 2014

                            Lead Product(s) : Metyrapone

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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