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Find Clinical Drug Pipeline Developments & Deals for Mavorixafor
Through the partnership, X4 Pharmaceuticals will distribute Xolremdi (mavorixafor), recently approved by the FDA. It is indicated for use in patients 12 years of age and older with warts, hypogammaglobulinemia, infections and myelokathexis syndrome.
Xolremdi (mavorixafor) is a selective CXC chemokine receptor 4 (CXCR4) antagonist, which is now approved for the treatment of WHIM syndrome in patients 12 years of age and older.
Mavorixafor is an investigational small-molecule antagonist of the CXCR4 receptor being developed as a once-daily oral therapy for WHIM syndrome and certain chronic neutropenic disorders.
X4P-001 (mavorixafor) is an investigational small-molecule antagonist of CXCR4 being developed as a once-daily oral therapy to correct the dysfunction resulting from the underlying causes of WHIM.
The financing will be used for the potential commercial launch of X4P-001 (mavorixafor) in individuals with WHIM syndrome and continue to advance mavorixafor for certain chronic neutropenic disorders.
X4 expects to use the proceedings for continued clinical development and commercial readiness of its lead candidate, X4P-001 (mavorixafor), an orally bioavailable CXCR4 antagonist.
X4P-001 (mavorixafor) is an investigational small-molecule antagonist of CXCR4 being developed as a once-daily oral therapy to correct the dysfunction resulting from the underlying causes of WHIM.
X4P-001 (mavorixafor) is a small molecule antagonist of chemokine receptor CXCR4. Due to mavorixafor’s ability to antagonize CXCR4 and improve the mobilization of WBC, mavorixafor has the potential to provide therapeutic benefit across a variety of immune system diseases.
X4P-001 (mavorixafor), a small molecule antagonist of chemokine receptor CXCR4 is being developed as an oral, once-daily therapy. Mavorixafor has the ability to antagonize CXCR4 and improve the mobilization of white blood cells.
Trial meets primary endpoint and first key secondary endpoint, with X4P-001 (mavorixafor) achieving statistically significant and clinically relevant longer times above threshold levels for both absolute neutrophil and absolute lymphocyte counts versus placebo.
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