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    Mavorixafor

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    Evotec

    Germany

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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    Evotec

    Germany

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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    USDMF CEP/COS JDMF EU-WC NDC arrow-down
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    NDC Package Code : 71924-0064

    Start Marketing Date : 2024-04-30

    End Marketing Date : 2025-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

     KDMF VMF Others AUDIT
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    Looking for 690656-53-2 / Mavorixafor API manufacturers, exporters & distributors?

    Mavorixafor manufacturers, exporters & distributors 1

    62

    PharmaCompass offers a list of Mavorixafor API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Mavorixafor manufacturer or Mavorixafor supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Mavorixafor manufacturer or Mavorixafor supplier.

    PharmaCompass also assists you with knowing the Mavorixafor API Price utilized in the formulation of products. Mavorixafor API Price is not always fixed or binding as the Mavorixafor Price is obtained through a variety of data sources. The Mavorixafor Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Mavorixafor

    Synonyms

    558447-26-0, Amd-070, Amd070, Amd11070, Amd 070, Amd-11070

    Cas Number

    690656-53-2

    Unique Ingredient Identifier (UNII)

    0G9LGB5O2W

    About Mavorixafor

    Mavorixafor is an orally bioavailable inhibitor of C-X-C chemokine receptor type 4 (CXCR4), with potential antineoplastic and immune checkpoint inhibitory activities. Upon administration, mavorixafor selectively binds to CXCR4 and prevents the binding of CXCR4 to its ligand, stromal cell-derived factor 1 (SDF-1 or CXCL12). This inhibits receptor activation and results in decreased proliferation and migration of CXCR4-overexpressing tumor cells. In addition, inhibition of CXCR4 prevents the recruitment of regulatory T-cells and myeloid-derived suppressor cells (MDSCs) to the tumor microenvironment, thereby abrogating CXCR4-mediated immunosuppression and enabling the activation of a cytotoxic T-lymphocyte-mediated immune response against cancer cells. The G protein-coupled receptor CXCR4, which is upregulated in several tumor cell types, induces the recruitment of immunosuppressive cells in the tumor microenvironment, suppresses immune surveillance, and promotes tumor angiogenesis and tumor cell proliferation. It is also a co-receptor for HIV entry into T-cells.

    Mavorixafor Manufacturers

    A Mavorixafor manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Mavorixafor, including repackagers and relabelers. The FDA regulates Mavorixafor manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Mavorixafor API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    Mavorixafor Suppliers

    A Mavorixafor supplier is an individual or a company that provides Mavorixafor active pharmaceutical ingredient (API) or Mavorixafor finished formulations upon request. The Mavorixafor suppliers may include Mavorixafor API manufacturers, exporters, distributors and traders.

    click here to find a list of Mavorixafor suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Mavorixafor Manufacturers | Traders | Suppliers

    Mavorixafor Manufacturers, Traders, Suppliers 1
    78

    We have 1 companies offering Mavorixafor

    Get in contact with the supplier of your choice:

    1. Evotec
    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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