Lead Product(s) : Nemvaleukin Alpha,Lucitanib
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Clovis Oncology
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The study evaluated the antitumor efficacy and mechanism of action of mALKS 4230, a mouse ortholog of ALKS 4230, and lucitanib as monotherapies and in combination in a preclinical syngeneic mouse model of colon cancer.
Product Name : ALKS 4230
Product Type : Protein
Upfront Cash : Inapplicable
June 22, 2020
Lead Product(s) : Nemvaleukin Alpha,Lucitanib
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Clovis Oncology
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Lucitanib,ALKS 4230
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Findings explore the pharmacokinetics (PK), pharmacodynamics (PD), and antitumor activity of Rubraca and lucitanib alone and in combination with other agents in preclinical models and simulated patient populations.
Product Name : CO-3810
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 17, 2020
Lead Product(s) : Lucitanib,ALKS 4230
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : First patient in the Phase 2 portion of the LIO-1 trial evaluating the combination of lucitanib and Opdivo® (nivolumab) for the treatment of gynecologic cancers. The LIO-1 trial is part of Clovis Oncology’s broad clinical collaboration with Bristol My...
Product Name : CO-3810
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 08, 2020