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                          Therapeutic Area by Lead Product

                          Study Phase by Lead Product

                          Company by Lead Product

                          Top Deals by Deal Size (USD bn)

                          01

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : Under the agreement, LEO Pharma will be responsible for commercialization and further development of SPEVIGO (Spesolimab). It is indicated for the treatment of generalized pustular psoriasis flares.

                          Product Name : Spevigo

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          July 14, 2025

                          Lead Product(s) : Spesolimab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Approved FDF

                          Recipient : Boehringer Ingelheim GmbH

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          02

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : LEO 138559 (temtokibart) is an investigational IL-22RA1 antagonist antibody candidate, which is being evaluated for the treatment of moderate-to-severe atopic dermatitis.

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          May 09, 2025

                          Lead Product(s) : Temtokibart

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Dermatology

                          Study Phase : Undisclosed

                          Recipient : Fondazione Policlinico Universitario Agostino Gemelli

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          March 19, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Dermatology

                          Highest Development Status : Undisclosed

                          Recipient : Fondazione Policlinico Universitario Agostino Gemelli

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : Anzupgo (delgocitinib) cream is an investigational, first-in-class, topical pan-JAK inhibitor for CHE. It is under clinical development for the treatment of Moderate to Severe Chronic Hand Eczema.

                          Product Name : Anzupgo

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          February 27, 2025

                          Lead Product(s) : Delgocitinib

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : Anzupgo (delgocitinib) cream is an investigational, first-in-class, topical pan-JAK inhibitor for CHE. It is under clinical development for the treatment of Moderate to Severe Chronic Hand Eczema.

                          Product Name : Anzupgo

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          February 04, 2025

                          Lead Product(s) : Delgocitinib

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : Through the partnership, LEO Pharma will be responsible for the distribution of Loqtorzi (toripalimab) in Europe. It is being indicated for the treatment of nasopharyngeal carcinoma.

                          Product Name : Loqtorzi

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          January 20, 2025

                          Lead Product(s) : Toripalimab,Cisplatin,Gemcitabine

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Recipient : Shanghai Junshi Biosciences

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          07

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Lead Product(s) : Tralokinumab

                          Therapeutic Area : Dermatology

                          Study Phase : Phase IV

                          Recipient : Psoriasis Treatment Center of Central New Jersey

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          January 14, 2025

                          Lead Product(s) : Tralokinumab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase IV

                          Recipient : Psoriasis Treatment Center of Central New Jersey

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : The partnership aims to accelerate the development and commercialization of LEO Pharma’s small molecule oral STAT6 programs for the potential treatment of patients with inflammatory diseases.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : $250.0 million

                          January 11, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : Gilead Sciences

                          Deal Size : $1,700.0 million

                          Deal Type : Partnership

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                          09

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : Anzupgo (delgocitinib) cream is an investigational, first-in-class, topical pan-JAK inhibitor. It is indicated for the treatment of Moderate to Severe Chronic Hand Eczema.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          November 14, 2024

                          Lead Product(s) : Delgocitinib

                          Therapeutic Area : Dermatology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          ChemOutsourcing
                          Not Confirmed
                          ChemOutsourcing
                          Not Confirmed

                          Details : Anzupgo (delgocitinib) cream is an investigational, first-in-class, topical pan-JAK inhibitor. It is indicated for the treatment of Moderate to Severe Chronic Hand Eczema.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 15, 2024

                          Lead Product(s) : Delgocitinib

                          Therapeutic Area : Dermatology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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