
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : JAB-23E73
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Oceanpine Capital
Deal Size : $28.1 million
Deal Type : Agreement
Jacobio Pharma Partners with Oceanpine Capital for Oncology Pipeline.
Details : The Proceeds from the transaction will primarily support R&D, production, and commercialization of Jacobio's Pan-KRAS inhibitor, JAB-23E73, and other oncology assets.
Product Name : JAB-23E73
Product Type : Miscellaneous
Upfront Cash : $17.6 million
October 15, 2025
Lead Product(s) : JAB-23E73
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Oceanpine Capital
Deal Size : $28.1 million
Deal Type : Agreement

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Lead Product(s) : JAB-23E73
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration
Details : JAB-23E73 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 15, 2025
Lead Product(s) : JAB-23E73
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : JAB-23E73
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : JAB-23E73 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 06, 2025
Lead Product(s) : JAB-23E73
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Glecirasib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Shanghai Allist Pharmaceuticals
Deal Size : $126.6 million
Deal Type : Licensing Agreement
Jacobio Licenses KRAS and SHP2 Inhibitors To Allist in China
Details : Jacobio has granted the China rights (including mainland China, Hong Kong, Macau, and Taiwan) of KRAS G12C inhibitor glecirasib and SHP2 inhibitor JAB-3312 to Shanghai Allist.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : $28.1 million
August 30, 2024
Lead Product(s) : Glecirasib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Shanghai Allist Pharmaceuticals
Deal Size : $126.6 million
Deal Type : Licensing Agreement

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Lead Product(s) : Glecirasib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Jacobio Pharma Announced its KRAS G12C Inhibitor Reached the Primary Endpoint
Details : JAB-21822 (glecirasib) is a KRAS G12C inhibitor, small molecule drug candidate which is currently being evaluated for the treatment of KRAS G12C mutated pancreatic cancer.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
April 30, 2024
Lead Product(s) : Glecirasib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : JAB-30355
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation
Details : JAB-30355 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
April 26, 2024
Lead Product(s) : JAB-30355
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : JAB-30300
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Jacobio Pharma Receives IND Approval for P53 Y220C Activator JAB-30300 in the U.S.
Details : JAB-30300 is an orally bioavailable small molecule, P53 Y220C activator, which is being evaluated for the treatment of patients with solid tumors harboring P53 Y220C mutation.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 01, 2024
Lead Product(s) : JAB-30300
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : JAB-3312,Glecirasib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Jacobio Gets China CDE Clearance for Phase III Trial Of SHP2 Plus KRAS G12C Inhibitor
Details : JAB-3312 is a highly selective SHP2 allosteric inhibitor, in combination with JAB-21822 (glecirasib), a KRAS G12C inhibitor is being evaluated for first-line NSCLC patients with KRAS G12C mutations.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 18, 2024
Lead Product(s) : JAB-3312,Glecirasib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Glecirasib,JAB-3312
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : JAB-21822 (glecirasib) is a KRAS G12C inhibitor developed by Jacobio and being developed in KRAS G12C-mutated locally advanced or metastatic pancreatic cancer patients.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 07, 2023
Lead Product(s) : Glecirasib,JAB-3312
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : JAB-3312
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : AbbVie Inc
Deal Size : Undisclosed
Deal Type : Termination
Jacobio Regains Global Rights to SHP2 Inhibitors
Details : Through the termination, Jacobio will regain the global rights previously granted to AbbVie for SHP2 inhibitor, JAB-3312, including decision-making authority over all development, commercialization, manufacturing, regulatory activities relating to SHP2 i...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
July 05, 2023
Lead Product(s) : JAB-3312
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : AbbVie Inc
Deal Size : Undisclosed
Deal Type : Termination
