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Find Clinical Drug Development Pipelines & Deals | PipelineProspector
Under the agreement, HilleVax gain rights to Kangh’s hexavalent virus-like particle (VLP) vaccine candidate for norovirus, referred to by HilleVax as HIL-216, outside of Greater China.
HQP1351 (olverembatinib) inhibited a panel of the Omicron-NTD-mediated cytokines tested, with a EC50 between 7.7 and 56 nM, demonstrating a wider range of concentrations than that of baricitinib.
New experimental data indicated that ASC10-A, an oral double prodrug of the antiviral nucleoside analog A showed potent cellular antiviral activity against Omicron variant (EC50 = 0.3µM), Delta variant (EC50 = 0.5µM) and wildtype virus (EC50 = 0.7µM).
SYZJ001 is screened from the "Ten-Trillion Innovative Antibody Discovery Platform", a platform over which Sanyou Biopharmaceuticals has independent intellectual property rights.
Under the arrangement, Simcere will obtain the exclusive right to develop, manufacture and commercialize the novel antiviral drug SIM0417 globally. Mutually striving to further contribute to the fight against the COVID-19 pandemic, both parties committed to working together.
Under the terms of agreement, Poly Pharm will manufacture clinical batches and, if approved, will also manufacture commercial batches for Celsion’s vaccine based on TheraPlas technology. TheraPlas underlies Celsion’s GEN-1 product and its PLACCINE vaccine technology platform.
Under the terms of the agreement, WuXi Bio will synthesize high yields of fully characterized, Good Laboratory Practice (GLP) grade SARS-CoV-2 s-protein required by BioVaxys for BVX-0320, its COVID-19 vaccine candidate, and for its Covid-T™ immunodiagnostic program.
Lead Product(s):
SARS-CoV-2 s-protein based vaccine
Qualigen Therapeutics has signed a contract with STA Pharmaceutical, a subsidiary of WuXi AppTec, for GMP production of AS1411, Qualigen's lead drug candidate for the treatment of COVID-19 and other viral diseases, for potential clinical trials.
The Company actively involves in development of anti-COVID-19 drugs with two candidates in pre-clinical phase, including HLX71 (S1 protein), and HLX70 (S1 protein).
This collaboration focuses on the clinical development to advance the clinical trials of CoronaVac, Sinovac’s inactivated vaccine candidate against COVID-19 to Phase III.