Lead Product(s) : HIL-216
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : HilleVax
Deal Size : $270.5 million
Deal Type : Licensing Agreement
HilleVax and Kangh Announce Agreement for Hexavalent VLP Norovirus Vaccine Outside China
Details : Under the agreement, HilleVax gain rights to Kangh’s hexavalent virus-like particle (VLP) vaccine candidate for norovirus, referred to by HilleVax as HIL-216, outside of Greater China.
Product Name : HIL-216
Product Type : Vaccine
Upfront Cash : $15.0 million
August 01, 2024
Lead Product(s) : HIL-216
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : HilleVax
Deal Size : $270.5 million
Deal Type : Licensing Agreement
Lead Product(s) : Olverembatinib
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : HQP1351 (olverembatinib) inhibited a panel of the Omicron-NTD-mediated cytokines tested, with a EC50 between 7.7 and 56 nM, demonstrating a wider range of concentrations than that of baricitinib.
Product Name : HQP1351
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 19, 2022
Lead Product(s) : Olverembatinib
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ASC10-A
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Business Update on ASC10, an Oral Double Prodrug Against COVID-19
Details : New experimental data indicated that ASC10-A, an oral double prodrug of the antiviral nucleoside analog A showed potent cellular antiviral activity against Omicron variant (EC50 = 0.3µM), Delta variant (EC50 = 0.5µM) and wildtype virus (EC50 = 0.7µM).
Product Name : ASC10-A
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 15, 2022
Lead Product(s) : ASC10-A
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : SYZJ001
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : SYZJ001 is screened from the "Ten-Trillion Innovative Antibody Discovery Platform", a platform over which Sanyou Biopharmaceuticals has independent intellectual property rights.
Product Name : SYZJ001
Product Type : Antibody
Upfront Cash : Inapplicable
November 22, 2021
Lead Product(s) : SYZJ001
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : SIM0417
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Shanghai Institute of Materia Medica
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the arrangement, Simcere will obtain the exclusive right to develop, manufacture and commercialize the novel antiviral drug SIM0417 globally. Mutually striving to further contribute to the fight against the COVID-19 pandemic, both parties committed...
Product Name : SIM0417
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
November 17, 2021
Lead Product(s) : SIM0417
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Shanghai Institute of Materia Medica
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : DNA-Based COVID-19 Vaccine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Imunon
Deal Size : Undisclosed
Deal Type : Agreement
Celsion and Hainan Poly Pharm Sign Agreement to Manufacture Celsion’s DNA-based Vaccine
Details : Under the terms of agreement, Poly Pharm will manufacture clinical batches and, if approved, will also manufacture commercial batches for Celsion’s vaccine based on TheraPlas technology. TheraPlas underlies Celsion’s GEN-1 product and its PLACCINE va...
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Undisclosed
September 17, 2021
Lead Product(s) : DNA-Based COVID-19 Vaccine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Imunon
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : SARS-CoV-2 s-protein Based Vaccine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Biovaxys
Deal Size : Undisclosed
Deal Type : Agreement
Details : Under the terms of the agreement, WuXi Bio will synthesize high yields of fully characterized, Good Laboratory Practice (GLP) grade SARS-CoV-2 s-protein required by BioVaxys for BVX-0320, its COVID-19 vaccine candidate, and for its Covid-T™ immunodiagn...
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Undisclosed
March 15, 2021
Lead Product(s) : SARS-CoV-2 s-protein Based Vaccine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Biovaxys
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Inactivated Vaccine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Institut Of Butantan
Deal Size : Undisclosed
Deal Type : Collaboration
Details : This collaboration focuses on the clinical development to advance the clinical trials of CoronaVac, Sinovac’s inactivated vaccine candidate against COVID-19 to Phase III.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Undisclosed
November 06, 2020
Lead Product(s) : Inactivated Vaccine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Institut Of Butantan
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : HLX71
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Shanghai Henlius Biotech, Inc. (2696 HK) – Expecting five NDA Approvals Within Two Years
Details : The Company actively involves in development of anti-COVID-19 drugs with two candidates in pre-clinical phase, including HLX71 (S1 protein), and HLX70 (S1 protein).
Product Name : HLX71
Product Type : Protein
Upfront Cash : Inapplicable
June 13, 2020
Lead Product(s) : HLX71
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : AS1411
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Qualigen Therapeutics
Deal Size : Undisclosed
Deal Type : Agreement
Qualigen Therapeutics Engages STA Pharmaceutical as GMP Manufacturer of AS1411 for Clinical Trials
Details : Qualigen Therapeutics has signed a contract with STA Pharmaceutical, a subsidiary of WuXi AppTec, for GMP production of AS1411, Qualigen's lead drug candidate for the treatment of COVID-19 and other viral diseases, for potential clinical trials.
Product Name : AS1411
Product Type : Oligonucleotide
Upfront Cash : Undisclosed
May 11, 2020
Lead Product(s) : AS1411
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Qualigen Therapeutics
Deal Size : Undisclosed
Deal Type : Agreement