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molecule","productStatus":"New Molecular Entity","date":"February 2020","url1":"","url2":"","graph1":"Small molecule","graph2":"CSL"}]

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            Recce® 327 an anti-infective compound which can be administered for intravenous, topical, nasal, oral and inhaled use. RECCE® 327’s universal mechanism of action has a patented ability to continuously kill bacteria without tendency for the emergence of resistance.

            Lead Product(s): R529

            Therapeutic Area: Infections and Infectious Diseases Product Name: R529

            Highest Development Status: Preclinical Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable January 11, 2023

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            Treatment with R327 (RECCE® 327) has shown to significantly reduce SARS-CoV-2 levels in a dose-dependent manner in throat swab samples collected from animals. This study provides proof-of-concept that IN treatment with R327 has the potential to reduce SARS-CoV-2 levels.

            Lead Product(s): R327

            Therapeutic Area: Infections and Infectious Diseases Product Name: RECCE 327

            Highest Development Status: Preclinical Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 18, 2022

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            Under the terms of the agreement, CSL Seqirus will deliver an H5N8 A/Astrakhan virus vaccine candidate and will then sponsor a subsequent Phase 2 clinical trial to evaluate the candidate along with CSL Seqirus' proprietary adjuvant MF59®.

            Lead Product(s): H5N8 A/Astrakhan Virus Vaccine,Squalene API

            Therapeutic Area: Infections and Infectious Diseases Product Name: H5N8 A/Astrakhan

            Highest Development Status: Preclinical Product Type: Vaccine

            Partner/Sponsor/Collaborator: BARDA

            Deal Size: $30.1 million Upfront Cash: Undisclosed

            Deal Type: Agreement October 06, 2022

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            The results demonstrate that the A(H5N1) sa-mRNA influenza vaccine candidate induced an anti-HA and anti-NA neutralizing response raised by sa-mRNA influenza vaccines at a dose as low as 0.01 µg in mice and also induced HA-specific CD4+ T cells.

            Lead Product(s): sa-mRNA Influenza Vaccine

            Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

            Highest Development Status: Preclinical Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 05, 2022

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            In consideration of research findings, the rapid evolution of the virus and changing treatment landscape presents significant challenges to conduct a clinical trial for SARS-CoV-2 with IMM-124E (travelan).

            Lead Product(s): Bovine Colostrum

            Therapeutic Area: Infections and Infectious Diseases Product Name: Travelan

            Highest Development Status: Preclinical Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable August 19, 2022

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            This Government Grant & Academic collaboration solidify Medlab’s transition to a true Biotech company. The NanoCelle® non-invasive nasal delivered vaccine is considered a “first in class” medicine delivery system.

            Lead Product(s): mRNA Vaccine

            Therapeutic Area: Infections and Infectious Diseases Product Name: Undisclosed

            Highest Development Status: Preclinical Product Type: Vaccine

            Partner/Sponsor/Collaborator: Macquarie University

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Collaboration January 14, 2022

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            Of the 36 candidates in clinical development, R327 is the only synthetic polymer drug candidate and the only clinical stage antibiotic for the indication of sepsis – globally.

            Lead Product(s): R327

            Therapeutic Area: Infections and Infectious Diseases Product Name: RECCE 327

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 26, 2021

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            Patented lead candidate RECCE® 327 as an intravenous therapy, is being developed for treatment of serious and potentially life-threatening infections including sepsis due to Gram-positive and Gramnegative bacteria including their superbug forms.

            Lead Product(s): R327

            Therapeutic Area: Infections and Infectious Diseases Product Name: R327

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable July 22, 2021

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            RECCE® 111 is a non-descript title for an experimental compound, developed in-house, building upon the unique mechanisms of action of RECCE® 327. Positive sinusitis infection data indicated in animal study.

            Lead Product(s): R327

            Therapeutic Area: Infections and Infectious Diseases Product Name: R327

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable April 01, 2021

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            The licensed technology combines Alterity’s PBT2 and other zinc ionophores with commonly used antibiotics to treat infections caused by multidrug resistant bacteria. This is an opportunity for Alterity to further leverage its investment in PBT2.

            Lead Product(s): PBT2

            Therapeutic Area: Infections and Infectious Diseases Product Name: PBT2

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Alterity Therapeutics

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Partnership December 21, 2020

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