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Inapplicable"},{"orgOrder":0,"company":"GSK","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"UNITED KINGDOM","productType":"Vaccine","year":"2020","type":"Inapplicable","leadProduct":"GSK3888550A","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"GSK","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"GSK \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"GSK \/ Inapplicable"},{"orgOrder":0,"company":"GSK","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"UNITED KINGDOM","productType":"Vaccine","year":"2021","type":"Inapplicable","leadProduct":"AS01","moa":"||Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase 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Inapplicable"},{"orgOrder":0,"company":"GSK","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"UNITED KINGDOM","productType":"Vaccine","year":"2022","type":"Inapplicable","leadProduct":"RSVPreF3 OA","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"GSK","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"GSK \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"GSK \/ Inapplicable"},{"orgOrder":0,"company":"GSK","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"UNITED KINGDOM","productType":"Vaccine","year":"2023","type":"Inapplicable","leadProduct":"RSVPreF3 OA","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase 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Inapplicable"},{"orgOrder":0,"company":"GSK","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"UNITED KINGDOM","productType":"Vaccine","year":"2023","type":"Inapplicable","leadProduct":"RSVPreF3 OA","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"GSK","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"GSK \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"GSK \/ Inapplicable"},{"orgOrder":0,"company":"GSK","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"UNITED KINGDOM","productType":"Vaccine","year":"2022","type":"Inapplicable","leadProduct":"AS01","moa":"||Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase 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Inapplicable"},{"orgOrder":0,"company":"GSK","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"UNITED KINGDOM","productType":"Vaccine","year":"2022","type":"Inapplicable","leadProduct":"AS01","moa":"||Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"GSK","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"GSK \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"GSK \/ Inapplicable"},{"orgOrder":0,"company":"GSK","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"UNITED KINGDOM","productType":"Antibiotic","year":"2023","type":"Inapplicable","leadProduct":"Gepotidacin","moa":"Bacterial DNA replication","graph1":"Infections and Infectious Diseases","graph2":"Phase 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Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"UNITED KINGDOM","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Ensifentrine","moa":"PDE3","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Verona Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Inhalation","sponsorNew":"Verona Pharma \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Verona Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Verona Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"UNITED KINGDOM","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Ensifentrine","moa":"PDE3","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Verona 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Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"UNITED KINGDOM","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Ensifentrine","moa":"PDE3","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Verona Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Oral Inhalation","sponsorNew":"Verona Pharma \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Verona Pharma \/ Inapplicable"}]

Find Drugs for Infections and Infectious Diseases in Phase III Clinical Development in UNITED KINGDOM

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                          01

                          IFT FIRST
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                          Details : GSK3511294 (depemokimab) is the first ultra-long-acting biologic with a binding affinity for IL-5. It is being evaluated for the treatment of severe asthma With an eosinophilic phenotype.

                          Product Name : GSK3511294

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          January 28, 2025

                          Lead Product(s) : Depemokimab

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : Shingrix (recombinant zoster vaccine) is a non-live, recombinant subunit vaccine, being evaluated as a prefilled syringe administration for prevention of shingles in at-risk adults aged 18 and over.

                          Product Name : Shingrix

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          January 27, 2025

                          Lead Product(s) : Zoster Vaccine Recombinant, Adjuvanted

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : Kavigale (sipavibart) is an investigational long-acting antibody, which is being evaluated in late-stage clinical trial studies for 12 year and older patients for the treatment of COVID-19.

                          Product Name : Kavigale

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          January 09, 2025

                          Lead Product(s) : Sipavibart

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : RQ Bio

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : The company will use the financing to advance its lead product candidate, F901318 (olorofim), which is in late-stage development and aimed at commercialization as a novel antifungal drug in the US.

                          Product Name : F901318

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          December 09, 2024

                          Lead Product(s) : Olorofim

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : AMR Action Fund

                          Deal Size : $100.0 million

                          Deal Type : Financing

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                          05

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : GSK3228836 (bepirovirsen) is an antisense oligonucleotide that targets all hepatitis B virus messenger RNAs. It is being developed for the treatment of chronic hepatitis B.

                          Product Name : GSK3228836

                          Product Type : Oligonucleotide

                          Upfront Cash : Inapplicable

                          December 02, 2024

                          Lead Product(s) : Bepirovirsen

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : GSK3511294 (depemokimab) is the first ultra-long-acting biologic with a binding affinity for IL-5. It is being evaluated for the treatment of chronic rhinosinusitis with nasal polyps.

                          Product Name : GSK3511294

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          October 14, 2024

                          Lead Product(s) : Depemokimab

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : Cabenuva is a combination of cabotegravir, which inhibits HIV integrase by blocking retroviral DNA integration, and rilpivirine, which inhibits HIV-1 reverse transcriptase.

                          Product Name : Cabenuva

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 03, 2024

                          Lead Product(s) : Cabotegravir,Rilpivirine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : Shingrix, a recombinant zoster vaccine, is under evaluation for shingles prevention in at-risk adults aged 18+.

                          Product Name : Shingrix

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          June 02, 2024

                          Lead Product(s) : Zoster Vaccine Recombinant, Adjuvanted

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          IFT FIRST
                          Not Confirmed
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                          Not Confirmed

                          Details : Arexvy (RSVPreF3) is a vaccine for preventing LRTD from RSV in individuals 60+. It's in phase 3 trials for RSV infections in those aged 50-59.

                          Product Name : Arexvy

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          June 02, 2024

                          Lead Product(s) : Respiratory Syncytial Virus Vaccine, Adjuvanted

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : AZD3152 (sipavibart) is an investigational long-acting antibody, which is being evaluated in late-stage clinical trial studies with patients for the treatment of COVID-19.

                          Product Name : AZD3152

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          May 20, 2024

                          Lead Product(s) : Sipavibart

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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