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BARDA"},{"orgOrder":0,"company":"Novartis Pharmaceuticals Corporation","sponsor":"Marcelo Iastrebner","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"SWITZERLAND","productType":"Miscellaneous","year":"2020","type":"Inapplicable","leadProduct":"Ruxolitinib Phosphate","moa":"tyrosine kinase inhibitors||Tyrosine-protein kinase JAK1 | Tyrosine-protein kinase JAK2","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Novartis Pharmaceuticals Corporation","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Novartis Pharmaceuticals Corporation \/ Marcelo Iastrebner","highestDevelopmentStatusID":"10","companyTruncated":"Novartis Pharmaceuticals Corporation \/ Marcelo Iastrebner"}]

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                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : BARDA

                            Deal Size : $39.0 million

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                            Basilea Receives Funding Under BARDA agreement to Advance Fosmanogepix and BAL2062

                            Details : The funding will be used to advance Basilea’s novel antifungals fosmanogepix and BAL2062 for patients with aspergillosis, candidiasis or other life-threatening fungal infections.

                            Product Name : APX-001

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            July 08, 2025

                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : BARDA

                            Deal Size : $39.0 million

                            Deal Type : Funding

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                            02

                            Basilea Pharmaceutica

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                            Basilea Pharmaceutica

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                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Biomedical Advanced Research and Development Authority

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Patients With Invasive Mold Inf...

                            Details : Fosmanogepix is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Invasive Fungal Infections.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            April 13, 2025

                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Biomedical Advanced Research and Development Authority

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            F. Hoffmann-La Roche

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                            F. Hoffmann-La Roche

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                            Lead Product(s) : Baloxavir Marboxil

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Study to Assess the Safety, Pharmacokinetics, and Efficacy of Baloxavir Marboxil in Chinese Pediatric Particip...

                            Details : Baloxavir Marboxil is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Influenza, Human.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            January 14, 2025

                            Lead Product(s) : Baloxavir Marboxil

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Basilea Pharmaceutica

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                            Basilea Pharmaceutica

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                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Basilea Initiates Phase 3 Study with Antifungal Fosmanogepix for Candidemia

                            Details : PF-07842805 (fosmanogepix), a potential first-in-class, clinical-stage broad-spectrum antifungal treatment candidate for Candidemia, including Candida auris, and invasive mold infections.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            September 23, 2024

                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Basilea Pharmaceutica

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                            Basilea Pharmaceutica

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                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : BARDA

                            Deal Size : $29.0 million

                            Deal Type : Funding

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                            Basilea Partners with BARDA To Develop Novel Antifungals, Gets Initial Funding

                            Details : The funding aims to support the development of Basilea’s clinical stage first-in-class antifungal, APX-001 (fosmanogepix), which is being investigated for the treatment of invasive candidiasis.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            September 19, 2024

                            Lead Product(s) : Fosmanogepix

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : BARDA

                            Deal Size : $29.0 million

                            Deal Type : Funding

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                            06

                            F. Hoffmann-La Roche

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                            F. Hoffmann-La Roche

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                            Lead Product(s) : Baloxavir Marboxil

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Positive Phase III Results Show Xofluza Reduces Influenza Virus Transmission

                            Details : Xofluza (baloxavir marboxil), a first-in-class, single-dose oral medicine with an innovative mechanism of action that has demonstrated efficacy in a wide range of influenza viruses.

                            Product Name : Xofluza

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            September 19, 2024

                            Lead Product(s) : Baloxavir Marboxil

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            F. Hoffmann-La Roche

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                            F. Hoffmann-La Roche

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                            Not Confirmed
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                            Lead Product(s) : Baloxavir Marboxil

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            A Surveillance Study of Susceptibility to Baloxavir Marboxil in Participants With Influenza

                            Details : Baloxavir Marboxil is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Influenza, Human.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            October 23, 2023

                            Lead Product(s) : Baloxavir Marboxil

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Basilea Pharmaceutica

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                            Not Confirmed

                            Basilea Pharmaceutica

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                            Not Confirmed
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                            Lead Product(s) : Ceftobiprole Medocaril

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Basilea Announces FDA Acceptance of New Drug Application for Antibiotic Ceftobiprole

                            Details : Zevtera (ceftobiprole medocaril sodium) is a cephalosporin antibiotic for intravenous administration, which is investigated for Staphylococcus aureus bacteremia (SAB), including right-sided infective endocarditis, acute bacterial skin and skin structure ...

                            Product Name : Zevtera

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            October 02, 2023

                            Lead Product(s) : Ceftobiprole Medocaril

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Basilea Pharmaceutica

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                            Basilea Pharmaceutica

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                            Not Confirmed
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                            Lead Product(s) : Ceftobiprole Medocaril

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Basilea Announces Submission of a New Drug Application to The US Food and Drug Administration for its Antibiot...

                            Details : Zevtera (ceftobiprole medocaril sodium) is a cephalosporin antibiotic for intravenous administration, with rapid bactericidal activity against a wide range of gram-positive and gram-negative bacteria.

                            Product Name : Zevtera

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            August 04, 2023

                            Lead Product(s) : Ceftobiprole Medocaril

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Basilea Pharmaceutica

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                            Basilea Pharmaceutica

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                            Not Confirmed
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                            Lead Product(s) : Ceftobiprole Medocaril

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Late-onset Sepsis in Term and Pre-term Neonates and Infants up to 3 Months of Age

                            Details : Ceftobiprole Medocaril is a Antibiotic drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Neonatal Sepsis.

                            Product Name : Undisclosed

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            May 12, 2023

                            Lead Product(s) : Ceftobiprole Medocaril

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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