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Details:
RECCE 327 (R327) is a rapid and irreversible bactericidal against gram-negative escherichia coli (E. coli) bacteria, in both active and stationary phase cells, which is being investigated as a treatment for sepsis and complicated/uncomplicated urinary tract infections.
Lead Product(s):
R327
Therapeutic Area: Infections and Infectious Diseases
Product Name: RECCE 327
Highest Development Status: Phase I
Product Type: Large molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
July 20, 2023
Details:
RECCE® 327 may be administered for intravenous, topical, nasal, oral and inhaled use, has patented ability to continuously kill bacteria without tendency for emergence of resistance, even with repeated use, indicating a unique ability to combat antibiotic resistant superbugs.
Lead Product(s):
R327
Therapeutic Area: Infections and Infectious Diseases
Product Name: RECCE 327
Highest Development Status: Phase I
Product Type: Large molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
October 03, 2022
Details:
Company report that in cohort seven of a Phase 1 clinical trial, RECCE® 327 (R327) intravenously dosed at 6,000mg (a 120-fold increase from cohort one at 50mg) over a 1-hour infusion demonstrated no serious adverse effects among 10 healthy male subjects.
Lead Product(s):
R327
Therapeutic Area: Infections and Infectious Diseases
Product Name: RECCE 327
Highest Development Status: Phase I
Product Type: Large molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
August 23, 2022
Details:
RECCE® 327 (R327) demonstrated a good safety and tolerability profile among 10 healthy male subjects intravenously dosed at 4,000mg (an 80-fold increase from cohort one at 50mg).
Lead Product(s):
R327
Therapeutic Area: Infections and Infectious Diseases
Product Name: RECCE 327
Highest Development Status: Phase I
Product Type: Large molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
June 22, 2022
Details:
In cohort five of a Phase I clinical trial, RECCE 327 (R327) demonstrated a good safety and tolerability profile among 10 healthy male subjects intravenously dosed at 2,000mg.
Lead Product(s):
R327
Therapeutic Area: Infections and Infectious Diseases
Product Name: RECCE 327
Highest Development Status: Phase I
Product Type: Large molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
May 23, 2022
Details:
RECCE 327 (R327), an intravenous and topical therapy was indicated to be safe and well-tolerated at 1,000mg with no clinically significant changes in vital signs or adverse events associated with R327.
Lead Product(s):
R327
Therapeutic Area: Infections and Infectious Diseases
Product Name: RECCE 327
Highest Development Status: Phase I
Product Type: Large molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
March 30, 2022
Details:
RECCE 327, a first new class of antibiotics with a universal mechanism of action that allows its compounds to continuously kill bacteria and multi-drug resistant superbugs, demonstrating good safety and tolerability profile – unanimously recommending cohort four to commence.
Lead Product(s):
Recce 327
Therapeutic Area: Infections and Infectious Diseases
Product Name: Recce 327
Highest Development Status: Phase I
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
March 08, 2022
Details:
Veyonda ® is the first drug candidate in the Company's pipeline, which is currently in a Phase 2 clinical trial. Veyonda (idronoxil) is a TBK1 (TANK-binding kinase 1) inhibitor, as an anti-inflammatory in patients with a moderate form of COVID-19.
Lead Product(s):
Idronoxil
Therapeutic Area: Infections and Infectious Diseases
Product Name: Veyonda
Highest Development Status: Phase I
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
August 25, 2021
Details:
Part 1 of the NOXCOVID-1 trial involved 26 patients and was a dose-escalation arm testing the safety of increasing (400, 600, 800, 1200, 1800 mg) daily Veyonda dosages.
Lead Product(s):
Idronoxil
Therapeutic Area: Infections and Infectious Diseases
Product Name: Veyonda
Highest Development Status: Phase I
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
March 18, 2021
Details:
The experimental anti-cancer drug, Veyonda®, joins a number of approved and experimental drugs with an anti-inflammatory action being tested globally for their ability to block rapid progression of COVID-19 disease from moderate to severe level.
Lead Product(s):
Idronoxil
Therapeutic Area: Infections and Infectious Diseases
Product Name: Veyonda
Highest Development Status: Phase I
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
October 08, 2020