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    [{"orgOrder":0,"company":"Alentis Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"SWITZERLAND","productType":"Antibody","year":"2025","type":"Inapplicable","leadProduct":"GlucoCorticoid","moa":"||CLDN1","graph1":"Immunology","graph2":"Phase II","graph3":"Alentis Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Alentis Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Alentis Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Alentis Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"SWITZERLAND","productType":"Antibody","year":"2023","type":"Inapplicable","leadProduct":"Glucocorticoid","moa":"||CLDN1","graph1":"Immunology","graph2":"Phase II","graph3":"Alentis Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Alentis Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Alentis Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"SHL Medical AG","sponsor":"MoonLake Immunotherapeutics","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"SWITZERLAND","productType":"Antibody","year":"2023","type":"Collaboration","leadProduct":"Adalimumab","moa":"||IL-17A\/IL-17F receptor","graph1":"Immunology","graph2":"Phase II","graph3":"SHL Medical AG","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"SHL Medical AG \/ MoonLake Immunotherapeutics","highestDevelopmentStatusID":"8","companyTruncated":"SHL Medical AG \/ MoonLake Immunotherapeutics"},{"orgOrder":0,"company":"Ferring Pharmaceuticals","sponsor":"I-Mab Biopharma","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"SWITZERLAND","productType":"Protein","year":"2022","type":"Collaboration","leadProduct":"Olamkicept","moa":"IL-6 receptor","graph1":"Immunology","graph2":"Phase II","graph3":"Ferring Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Ferring Pharmaceuticals \/ I-Mab Biopharma","highestDevelopmentStatusID":"8","companyTruncated":"Ferring Pharmaceuticals \/ I-Mab Biopharma"},{"orgOrder":0,"company":"BaseLaunch","sponsor":"Bridge Biotherapeutics","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"SWITZERLAND","productType":"Peptide","year":"2020","type":"Partnership","leadProduct":"BBT-401","moa":"Pellino-1","graph1":"Immunology","graph2":"Phase II","graph3":"BaseLaunch","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"BaseLaunch \/ Bridge Biotherapeutics","highestDevelopmentStatusID":"8","companyTruncated":"BaseLaunch \/ Bridge Biotherapeutics"},{"orgOrder":0,"company":"VectivBio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"SWITZERLAND","productType":"Peptide","year":"2022","type":"Inapplicable","leadProduct":"Apraglutide","moa":"GLP-2 receptor","graph1":"Immunology","graph2":"Phase II","graph3":"VectivBio","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"VectivBio \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"VectivBio \/ Inapplicable"},{"orgOrder":0,"company":"VectivBio","sponsor":"Asahi Kasei Pharma","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"SWITZERLAND","productType":"Peptide","year":"2023","type":"Inapplicable","leadProduct":"Apraglutide","moa":"GLP-2 receptor","graph1":"Immunology","graph2":"Phase II","graph3":"VectivBio","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"VectivBio \/ Asahi Kasei Pharma","highestDevelopmentStatusID":"8","companyTruncated":"VectivBio \/ Asahi Kasei Pharma"},{"orgOrder":0,"company":"VectivBio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"SWITZERLAND","productType":"Peptide","year":"2022","type":"Inapplicable","leadProduct":"Apraglutide","moa":"GLP-2 receptor","graph1":"Immunology","graph2":"Phase II","graph3":"VectivBio","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"VectivBio \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"VectivBio \/ Inapplicable"},{"orgOrder":0,"company":"VectivBio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"SWITZERLAND","productType":"Peptide","year":"2021","type":"Inapplicable","leadProduct":"Apraglutide","moa":"GLP-2 receptor","graph1":"Immunology","graph2":"Phase II","graph3":"VectivBio","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"VectivBio \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"VectivBio \/ Inapplicable"}]

    Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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                            01

                            Alentis Therapeutics

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                            Alentis Therapeutics

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                            Lead Product(s) : Lixudebart,GlucoCorticoid,Rituximab

                            Therapeutic Area : Immunology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Alentis Announces Positive Results for Lixudebart in ANCA-RPGN Liver Fibrosis

                            Details : ALE.F02 (lixudebart) is a claudin 1 inhibitor antibody, which is currently being evaluated for antineutrophil cytoplasmic antibody-associated vasculitis with rapidly progressive glomerulonephritis.

                            Product Name : ALE.F02

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            January 09, 2025

                            Lead Product(s) : Lixudebart,GlucoCorticoid,Rituximab

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            MoonLake Immunotherapeutics

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                            MoonLake Immunotherapeutics

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                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Immunology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            MoonLake Announces Positive FDA and EMA Feedback for Ph 3 of Sonelokimab in Arthritis

                            Details : M1095 (sonelokimab) is an investigational 40kDa humanized nanobody. It is currently being assessed in lead indications of pateints suffering from psoriatic arthritis.

                            Product Name : M1095

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            October 06, 2024

                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            MoonLake Immunotherapeutics

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                            MoonLake Immunotherapeutics

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                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Immunology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            MoonLake Completes Patient Randomization Ahead of Schedule for its Phase 2 Trial in Active Psoriatic Arthritis...

                            Details : M1095 (sonelokimab) is a humanized nanobody consisting of three VHH domains covalently linked by flexible glycine-serine spacers. It selectively binds with IL-17A and IL-17F and inhibit IL-17A/A, IL-17A/F, and IL-17F/F dimer, which investigated for psori...

                            Product Name : M1095

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            July 25, 2023

                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            MoonLake Immunotherapeutics

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                            MoonLake Immunotherapeutics

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                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Immunology

                            Study Phase : Phase II

                            Sponsor : SVB Securities

                            Deal Size : $250.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            MoonLake Immunotherapeutics Announces Proposed Underwritten Public Offering

                            Details : MoonLake intends to use the proceeds to fund the ongoing advancement of M1095, a novel investigational Nanobody® for the treatment of inflammatory disease. Sonelokimab inhibits IL-17A and IL-17F by inhibiting the IL-17A/A, IL-17A/F, and IL-17F/F dimers ...

                            Product Name : M1095

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            June 26, 2023

                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase II

                            Sponsor : SVB Securities

                            Deal Size : $250.0 million

                            Deal Type : Public Offering

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                            05

                            Alentis Therapeutics

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                            Alentis Therapeutics

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                            Lead Product(s) : Lixudebart,Glucocorticoid,Rituximab

                            Therapeutic Area : Immunology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Alentis Therapeutics Doses First ANCA-Associated Vasculitis Rapidly Progressive Glomerulonephritis Patient in ...

                            Details : ALE.F02 (Lixudebart Rituximab GlucoCorticoid) is a claudin 1 inhibitor antibody drug candidate, which is currently being evaluated for the treatment of antineutrophil cytoplasmic antibody-associated vasculitis with rapidly progressive glomerulonephritis.

                            Product Name : ALE.F02

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            May 12, 2023

                            Lead Product(s) : Lixudebart,Glucocorticoid,Rituximab

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            VectivBio

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                            VectivBio

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                            Lead Product(s) : Apraglutide

                            Therapeutic Area : Immunology

                            Study Phase : Phase II

                            Sponsor : Asahi Kasei Pharma

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            VectivBio and Asahi Kasei Pharma Announce the Start of a Phase 1 Study of Apraglutide in Japan

                            Details : Apraglutide is a novel long-acting glucagon-like peptide-2 analog designed for to increase fluid and nutrient absorption by the remnant intestine of patients who have short bowel syndrome with intestinal insufficiency or intestinal failure.

                            Product Name : FE203799

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            March 13, 2023

                            Lead Product(s) : Apraglutide

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase II

                            Sponsor : Asahi Kasei Pharma

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            SHL Medical AG

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                            SHL Medical AG

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                            Lead Product(s) : Sonelokimab,Adalimumab

                            Therapeutic Area : Immunology

                            Study Phase : Phase II

                            Sponsor : MoonLake Immunotherapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            MoonLake Immunotherapeutics and SHL Medical Collaborate To Jointly Develop An Autoinjector For Sonelokimab Sup...

                            Details : The collaboration aims to develop an autoinjector for clinical and potential subsequent commercial supply of MoonLake’s Nanobody® M1095 (sonelokimab) by using SHL Medical's market-proven Molly® modular platform technology.

                            Product Name : M1095

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            March 05, 2023

                            Lead Product(s) : Sonelokimab,Adalimumab

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase II

                            Sponsor : MoonLake Immunotherapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            08

                            MoonLake Immunotherapeutics

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                            MoonLake Immunotherapeutics

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                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Immunology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            MoonLake Immunotherapeutics screens first patient in Phase 2 study of the Nanobody® sonelokimab in active pso...

                            Details : MoonLake plans to execute on its development program to unlock the potential of M1095 (Sonelokimab), the novel investigational Nanobody® for the treatment of inflammation, to revolutionize outcomes for patients with inflammatory diseases.

                            Product Name : M1095

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            December 14, 2022

                            Lead Product(s) : Sonelokimab

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Ferring Pharmaceuticals

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                            Ferring Pharmaceuticals

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                            Lead Product(s) : Olamkicept

                            Therapeutic Area : Immunology

                            Study Phase : Phase II

                            Sponsor : I-Mab Biopharma

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Ferring Announces New Collaboration for Development of Olamkicept

                            Details : This new collaboration enables Ferring to invest in the development of olamkicept globally and provides an option for I-Mab to collaborate with Ferring in the future development of olamkicept at a pre-defined development milestone.

                            Product Name : TJ-301

                            Product Type : Protein

                            Upfront Cash : Undisclosed

                            September 06, 2022

                            Lead Product(s) : Olamkicept

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase II

                            Sponsor : I-Mab Biopharma

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            10

                            VectivBio

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                            VectivBio

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                            Lead Product(s) : Apraglutide

                            Therapeutic Area : Immunology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            VectivBio Announces First Two Patients Dosed in Phase 2 STARGAZE Study of Apraglutide for the Treatment of Acu...

                            Details : FE203799 (apraglutide) is a next-generation, synthetic GLP-2 analog rationally designed with the potential to offer an improved safety and efficacy profile relative to other agents in its class and less frequent dosing.

                            Product Name : FE203799

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            February 06, 2022

                            Lead Product(s) : Apraglutide

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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