
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Bomedemstat
Therapeutic Area : Hematology
Study Phase : Phase II
Sponsor : Merck & Co
Deal Size : $1,350.0 million
Deal Type : Acquisition
Merck Completes Tender Offer to Acquire Imago BioSciences, Inc.
Details : Under the acquisition agreement, Merck will strengthens the presence in the growing field of hematology by also acquiring pipeline of Imago, having lead candidate IMG-7289 (bomedemstat), an investigational orally available lysine-specific demethylase 1 (...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : $1,350.0 million
January 11, 2023
Lead Product(s) : Bomedemstat
Therapeutic Area : Hematology
Highest Development Status : Phase II
Sponsor : Merck & Co
Deal Size : $1,350.0 million
Deal Type : Acquisition

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Lead Product(s) : Bomedemstat,Ruxolitinib Phosphate
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Phase 2 study of IMG-7289 (bomedemstat), an investigational oral lysine-specific demethylase 1 (LSD1) inhibitor, in combination with ruxolitinib (Jakafi®) in people with myelofibrosis (MF) conducted at the Department of Medicine, Queen Mary Hospital.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 20, 2022
Lead Product(s) : Bomedemstat,Ruxolitinib Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Bomedemstat,Venetoclax
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : IMG-7289 (bomedemstat), an investigational oral lysine-specific demethylase 1 (LSD1) inhibitor, has been generally well-tolerated and has demonstrated significant symptom improvement for patients with myelofibrosis and essential thrombocythemia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 30, 2022
Lead Product(s) : Bomedemstat,Venetoclax
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Bomedemstat
Therapeutic Area : Hematology
Study Phase : Phase II
Sponsor : Merck & Co
Deal Size : $1,350.0 million
Deal Type : Acquisition
Merck to Acquire Imago BioSciences, Inc.
Details : Under the acquisition agreement, Merck will strengthens the presence in the growing field of hematology by also acquiring pipeline of Imago, having lead candidate bomedemstat (IMG-7289), an investigational orally available lysine-specific demethylase 1 (...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : $1,350.0 million
November 21, 2022
Lead Product(s) : Bomedemstat
Therapeutic Area : Hematology
Highest Development Status : Phase II
Sponsor : Merck & Co
Deal Size : $1,350.0 million
Deal Type : Acquisition

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Lead Product(s) : Bomedemstat
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Terrence J Bradley, MD
Deal Size : Inapplicable
Deal Type : Inapplicable
Venetoclax and Bomedemstat in Patients with Relapsed/Refractory Acute Myeloid Leukemia
Details : Bomedemstat is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Leukemia, Myeloid, Acute.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 28, 2022
Lead Product(s) : Bomedemstat
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Terrence J Bradley, MD
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Bomedemstat
Therapeutic Area : Oncology
Study Phase : Phase II
Recipient : University of Hong Kong
Deal Size : Inapplicable
Deal Type : Inapplicable
Bomedemstat (IMG-7289) Plus Ruxolitinib for Myelofibrosis
Details : Bomedemstat is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Primary Myelofibrosis.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 06, 2022
Lead Product(s) : Bomedemstat
Therapeutic Area : Oncology
Highest Development Status : Phase II
Recipient : University of Hong Kong
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Bomedemstat
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Study of Bomedemstat (MK-3543) in Participants With Polycythemia Vera (MK-3543-004)
Details : Bomedemstat is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Polycythemia Vera.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 28, 2022
Lead Product(s) : Bomedemstat
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Bomedemstat
Therapeutic Area : Hematology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : As of the data cutoff of, IMG-7289 (bomedemstat) demonstrated durability of response with 81% of patients achieving normalized platelet counts for at least 12 weeks.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 10, 2022
Lead Product(s) : Bomedemstat
Therapeutic Area : Hematology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Bomedemstat
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : IMG-7289 (bomedemstat, an orally available, small molecule inhibitor of LSD1, is the lead product candidate discovered by Imago for the treatment of certain myeloproliferative neoplasms (MPNs), a family of related, chronic cancers of the bone marrow.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 10, 2022
Lead Product(s) : Bomedemstat
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Bomedemstat
Therapeutic Area : Hematology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : IMG-7289 (bomedemstat), an orally available, small molecule inhibitor of LSD1, is the lead product candidate discovered by Imago for the treatment of certain myeloproliferative neoplasms (MPNs), a family of related, chronic cancers of the bone marrow.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 12, 2022
Lead Product(s) : Bomedemstat
Therapeutic Area : Hematology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
