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Pharmaceuticals","amount2":0.40999999999999998,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0.41999999999999998,"dosageForm":"Undisclosed","sponsorNew":"Idorsia Pharmaceuticals \/ Neurocrine Biosciences","highestDevelopmentStatusID":"6","companyTruncated":"Idorsia Pharmaceuticals \/ Neurocrine Biosciences"},{"orgOrder":0,"company":"Idorsia Pharmaceuticals","sponsor":"Neurocrine Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"SWITZERLAND","productType":"Miscellaneous","year":"2020","type":"Licensing Agreement","leadProduct":"ACT-709478","moa":"Voltage-gated T-type calcium channel","graph1":"Neurology","graph2":"Phase I","graph3":"Idorsia Pharmaceuticals","amount2":0.41999999999999998,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0.41999999999999998,"dosageForm":"Undisclosed","sponsorNew":"Idorsia Pharmaceuticals \/ Neurocrine Biosciences","highestDevelopmentStatusID":"6","companyTruncated":"Idorsia Pharmaceuticals \/ Neurocrine Biosciences"},{"orgOrder":0,"company":"Idorsia Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"SWITZERLAND","productType":"Undisclosed","year":"2021","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Undisclosed","graph2":"Phase I","graph3":"Idorsia Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Idorsia Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Idorsia Pharmaceuticals \/ Undisclosed"}]

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                            01

                            Idorsia Pharmaceuticals

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                            Lead Product(s) : IDOR-1134-2831

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Idorsia Validates Synthetic Glycan Vaccine Platform In Humans

                            Details : Idorsia’s vaccine IDOR-1134-2831 is intended to be developed for the prevention of CDI in patients at risk in hospital and community settings, with the potential to eradicate bacteria and spores.

                            Product Name : IDOR-1134-2831

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            June 30, 2025

                            Lead Product(s) : IDOR-1134-2831

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Idorsia Pharmaceuticals

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                            Lead Product(s) : Aprocitentan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            US FDA Approves an Updated Label for TRYVIO (aprocitentan) Removing the REMS Requirement

                            Details : Tryvio (aprocitentan) is a first and only endothelin receptor antagonist, which is indicated for the treatment of hypertension.

                            Product Name : Tryvio

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            April 09, 2025

                            Lead Product(s) : Aprocitentan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Idorsia Pharmaceuticals

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                            Lead Product(s) : Cenerimod

                            Therapeutic Area : Immunology

                            Study Phase : Phase III

                            Sponsor : Viatris

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Idorsia and Viatris Update their Collaboration for Selatogrel and Cenerimod

                            Details : The collaboration aims for the global development and commercialization rights to ACT-246475 (selatogrel), a reversible, and selective 2-phenylprimdine-4-carboxamide and ACT-334441 (cenerimod).

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : $350.0 million

                            February 26, 2025

                            Lead Product(s) : Cenerimod

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase III

                            Sponsor : Viatris

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            04

                            Idorsia Pharmaceuticals

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                            Lead Product(s) : Ethinyl Estradiol

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Drug-drug Interaction Trial in Healthy Female Participants to Investigate the Effect of Aprocitentan on Comb...

                            Details : Ethinyl estradiol is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            January 29, 2025

                            Lead Product(s) : Ethinyl Estradiol

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Idorsia Pharmaceuticals

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                            Lead Product(s) : Vamorolone

                            Therapeutic Area : Genetic Disease

                            Study Phase : Approved FDF

                            Sponsor : R-Bridge Healthcare Fund

                            Deal Size : $30.0 million

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Santhera Pharmaceuticals Updates Royalty Agreement for AGAMREE® (Vamorolone)

                            Details : Idorsia transfers rights to royalties and milestones for Agamree (vamorolone), a dissociative steroid with novel mode of action in patients with Duchenne muscular dystrophy, to R-Bridge Healthcare.

                            Product Name : Agamree

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            January 16, 2025

                            Lead Product(s) : Vamorolone

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Approved FDF

                            Sponsor : R-Bridge Healthcare Fund

                            Deal Size : $30.0 million

                            Deal Type : Agreement

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                            06

                            Idorsia Pharmaceuticals

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                            Lead Product(s) : Aprocitentan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Idorsia Launches TRYVIO™ in the U.S. for Hard-to-Control Hypertension

                            Details : Tryvio (aprocitentan) is a first and only endothelin receptor antagonist, which is indicated for the treatment of hypertension in adult patients, in combination with other antihypertensive drugs.

                            Product Name : Tryvio

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            November 15, 2024

                            Lead Product(s) : Aprocitentan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Idorsia Pharmaceuticals

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                            Lead Product(s) : Cenerimod

                            Therapeutic Area : Immunology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Long-term Safety and Tolerability of Cenerimod in Adults With Systemic Lupus Erythematosus

                            Details : Cenerimod is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Lupus Erythematosus, Systemic.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            June 26, 2024

                            Lead Product(s) : Cenerimod

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Idorsia Pharmaceuticals

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                            Lead Product(s) : OKN4395

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Owkin

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Owkin Unveils AI-Driven Oncology & Immunology Pipeline, In-Licenses Best-in-Class OKN4395

                            Details : Owkin in-licensed OKN4395, a highly selective, potent, clinic-ready best-in-class dual inhibitor of prostanoid receptors EP2 and EP4, from Idorsia that will enter Phase 1 trials in early 2025.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            May 23, 2024

                            Lead Product(s) : OKN4395

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Owkin

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            09

                            Idorsia Pharmaceuticals

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                            Lead Product(s) : Aprocitentan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            JERAYGO Recommended for Approval in Europe for Resistant Hypertension Treatment

                            Details : Jeraygo (aprocitentan), the first endothelin receptor antagonist, treats hypertension in adults by combining it with other antihypertensives to reduce blood pressure.

                            Product Name : Jeraygo

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            April 26, 2024

                            Lead Product(s) : Aprocitentan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Idorsia Pharmaceuticals

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                            Lead Product(s) : Aprocitentan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            US FDA Approves Idorsia's TRYVIO As First Endothelin Antagonist for High Blood Pressure

                            Details : Tryvio (aprocitentan), an endothelin receptor antagonist, is indicated for treating hypertension when combined with other antihypertensives to lower blood pressure in adults.

                            Product Name : Tryvio

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            March 20, 2024

                            Lead Product(s) : Aprocitentan

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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