[{"orgOrder":0,"company":"UConn Health","sponsor":"SHIRE PLC | Yale University","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Miscellaneous","year":"2017","type":"Inapplicable","leadProduct":"Guanfacine","moa":"Adrenergic receptor alpha-2","graph1":"Psychiatry\/Psychology","graph2":"Phase IV","graph3":"UConn Health","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Tablet, Extended Release","sponsorNew":"UConn Health \/ SHIRE PLC | Yale University","highestDevelopmentStatusID":"11","companyTruncated":"UConn Health \/ SHIRE PLC | Yale University"},{"orgOrder":0,"company":"Children's Specialized Hospital","sponsor":"SHIRE PLC","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Miscellaneous","year":"2010","type":"Inapplicable","leadProduct":"Guanfacine","moa":"Adrenergic receptor alpha-2","graph1":"Psychiatry\/Psychology","graph2":"Phase IV","graph3":"Children's Specialized Hospital","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Children's Specialized Hospital \/ SHIRE PLC","highestDevelopmentStatusID":"11","companyTruncated":"Children's Specialized Hospital \/ SHIRE PLC"},{"orgOrder":0,"company":"Neurology Group of Bergen County, P.A.","sponsor":"SHIRE PLC","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Miscellaneous","year":"2010","type":"Inapplicable","leadProduct":"Guanfacine","moa":"Adrenergic receptor alpha-2","graph1":"Psychiatry\/Psychology","graph2":"Phase IV","graph3":"Neurology Group of Bergen County, P.A.","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Neurology Group of Bergen County, P.A. \/ SHIRE PLC","highestDevelopmentStatusID":"11","companyTruncated":"Neurology Group of Bergen County, P.A. \/ SHIRE PLC"},{"orgOrder":0,"company":"New York State Psychiatric Institute","sponsor":"SHIRE PLC","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Miscellaneous","year":"2014","type":"Inapplicable","leadProduct":"Guanfacine","moa":"Adrenergic receptor alpha-2","graph1":"Psychiatry\/Psychology","graph2":"Phase IV","graph3":"New York State Psychiatric Institute","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"New York State Psychiatric Institute \/ SHIRE PLC","highestDevelopmentStatusID":"11","companyTruncated":"New York State Psychiatric Institute \/ SHIRE PLC"},{"orgOrder":0,"company":"New York State Psychiatric Institute","sponsor":"Columbia University | American Academy of Child Adolescent Psychiatry | SHIRE PLC","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Miscellaneous","year":"2014","type":"Inapplicable","leadProduct":"Guanfacine","moa":"Adrenergic receptor alpha-2","graph1":"Psychiatry\/Psychology","graph2":"Undisclosed","graph3":"New York State Psychiatric Institute","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"New York State Psychiatric Institute \/ Columbia University | American Academy of Child Adolescent Psychiatry | SHIRE PLC","highestDevelopmentStatusID":"1","companyTruncated":"New York State Psychiatric Institute \/ Columbia University | American Academy of Child Adolescent Psychiatry | SHIRE PLC"},{"orgOrder":0,"company":"University of Texas Health Science Center at San Antonio","sponsor":"SHIRE PLC","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"U.S.A","productType":"Miscellaneous","year":"2010","type":"Inapplicable","leadProduct":"Guanfacine","moa":"Adrenergic receptor alpha-2","graph1":"Psychiatry\/Psychology","graph2":"Phase IV","graph3":"University of Texas Health Science Center at San Antonio","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Tablet, Extended Release","sponsorNew":"University of Texas Health Science Center at San Antonio \/ SHIRE PLC","highestDevelopmentStatusID":"11","companyTruncated":"University of Texas Health Science Center at San Antonio \/ SHIRE PLC"},{"orgOrder":0,"company":"NYU Langone Health","sponsor":"Winthrop University Hospital","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Miscellaneous","year":"2019","type":"Inapplicable","leadProduct":"Guanfacine","moa":"Adrenergic receptor alpha-2","graph1":"Genetic Disease","graph2":"Phase IV","graph3":"NYU Langone Health","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"NYU Langone Health \/ Winthrop University Hospital","highestDevelopmentStatusID":"11","companyTruncated":"NYU Langone Health \/ Winthrop University Hospital"},{"orgOrder":0,"company":"Lori A. Schweickert, MD","sponsor":"SHIRE PLC","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"","productType":"Miscellaneous","year":"2010","type":"Inapplicable","leadProduct":"Guanfacine","moa":"Adrenergic receptor alpha-2","graph1":"Psychiatry\/Psychology","graph2":"Phase IV","graph3":"Lori A. Schweickert, MD","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Tablet, Extended Release","sponsorNew":"Lori A. Schweickert, MD \/ SHIRE PLC","highestDevelopmentStatusID":"11","companyTruncated":"Lori A. Schweickert, MD \/ SHIRE PLC"},{"orgOrder":0,"company":"Maastricht University Medical Center","sponsor":"SHIRE PLC","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"NETHERLANDS","productType":"Miscellaneous","year":"2018","type":"Inapplicable","leadProduct":"Guanfacine","moa":"Adrenergic receptor alpha-2","graph1":"Psychiatry\/Psychology","graph2":"Phase III","graph3":"Maastricht University Medical Center","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Maastricht University Medical Center \/ SHIRE PLC","highestDevelopmentStatusID":"10","companyTruncated":"Maastricht University Medical Center \/ SHIRE PLC"},{"orgOrder":0,"company":"SHIRE PLC","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"IRELAND","productType":"Miscellaneous","year":"2011","type":"Inapplicable","leadProduct":"Guanfacine","moa":"Adrenergic receptor alpha-2","graph1":"Psychiatry\/Psychology","graph2":"Phase IV","graph3":"SHIRE PLC","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"SHIRE PLC \/ Undisclosed","highestDevelopmentStatusID":"11","companyTruncated":"SHIRE PLC \/ Undisclosed"},{"orgOrder":0,"company":"SHIRE PLC","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"IRELAND","productType":"Miscellaneous","year":"2011","type":"Inapplicable","leadProduct":"Guanfacine","moa":"Adrenergic receptor alpha-2","graph1":"Psychiatry\/Psychology","graph2":"Phase II","graph3":"SHIRE PLC","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"SHIRE PLC \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"SHIRE PLC \/ Undisclosed"},{"orgOrder":0,"company":"SHIRE PLC","sponsor":"Takeda Pharmaceutical","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"IRELAND","productType":"Miscellaneous","year":"2019","type":"Inapplicable","leadProduct":"Guanfacine","moa":"Adrenergic receptor alpha-2","graph1":"Psychiatry\/Psychology","graph2":"Phase IV","graph3":"SHIRE PLC","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"SHIRE PLC \/ Takeda Pharmaceutical","highestDevelopmentStatusID":"11","companyTruncated":"SHIRE PLC \/ Takeda Pharmaceutical"},{"orgOrder":0,"company":"SHIRE PLC","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"IRELAND","productType":"Miscellaneous","year":"2010","type":"Inapplicable","leadProduct":"Guanfacine","moa":"Adrenergic receptor alpha-2","graph1":"Psychiatry\/Psychology","graph2":"Phase IV","graph3":"SHIRE PLC","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"SHIRE PLC \/ Undisclosed","highestDevelopmentStatusID":"11","companyTruncated":"SHIRE PLC \/ Undisclosed"},{"orgOrder":0,"company":"SHIRE PLC","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"IRELAND","productType":"Miscellaneous","year":"2010","type":"Inapplicable","leadProduct":"Guanfacine","moa":"Adrenergic receptor alpha-2","graph1":"Psychiatry\/Psychology","graph2":"Phase IV","graph3":"SHIRE PLC","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"SHIRE PLC \/ Undisclosed","highestDevelopmentStatusID":"11","companyTruncated":"SHIRE PLC \/ Undisclosed"},{"orgOrder":0,"company":"SHIRE PLC","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Psychiatry\/Psychology","country":"IRELAND","productType":"Miscellaneous","year":"2010","type":"Inapplicable","leadProduct":"Guanfacine","moa":"Adrenergic receptor alpha-2","graph1":"Psychiatry\/Psychology","graph2":"Phase IV","graph3":"SHIRE PLC","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Psychiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"SHIRE PLC \/ Undisclosed","highestDevelopmentStatusID":"11","companyTruncated":"SHIRE PLC \/ Undisclosed"},{"orgOrder":0,"company":"Yale University","sponsor":"Icahn School of Medicine at Mount Sinai | University of South Florida | SHIRE PLC | New York University","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Miscellaneous","year":"2012","type":"Inapplicable","leadProduct":"Guanfacine","moa":"Adrenergic receptor alpha-2","graph1":"Neurology","graph2":"Phase IV","graph3":"Yale University","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Yale University \/ Icahn School of Medicine at Mount Sinai | University of South Florida | SHIRE PLC | New York University","highestDevelopmentStatusID":"11","companyTruncated":"Yale University \/ Icahn School of Medicine at Mount Sinai | University of South Florida | SHIRE PLC | New York University"},{"orgOrder":0,"company":"Rachel G. Greenberg, MD, MB, MHS","sponsor":"The Emmes Company, LLC | Gansu Provincial Maternal and Child Health Care Hospital","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"Guanfacine","moa":"Adrenergic receptor alpha-2","graph1":"Genetic Disease","graph2":"Phase II","graph3":"Rachel G. Greenberg, MD, MB, MHS","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Rachel G. Greenberg, MD, MB, MHS \/ The Emmes Company, LLC | Gansu Provincial Maternal and Child Health Care Hospital","highestDevelopmentStatusID":"8","companyTruncated":"Rachel G. Greenberg, MD, MB, MHS \/ The Emmes Company, LLC | Gansu Provincial Maternal and Child Health Care Hospital"}]

Find Clinical Drug Pipeline Developments & Deals for Guanfacine

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Rachel G. Greenberg, MD, MB, MHS

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Rachel G. Greenberg, MD, MB, MHS

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Lead Product(s) : Guanfacine

                          Therapeutic Area : Genetic Disease

                          Study Phase : Phase II

                          Sponsor : The Emmes Company, LLC | Gansu Provincial Maternal and Child Health Care Hospital

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Guanfacine HCl is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Down Syndrome.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          September 18, 2023

                          Lead Product(s) : Guanfacine

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase II

                          Sponsor : The Emmes Company, LLC | Gansu Provincial Maternal and Child Health Care Hospital

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Guanfacine HCl is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Attention Deficit Disorder with Hyperactivity.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          September 11, 2019

                          Lead Product(s) : Guanfacine

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase IV

                          Sponsor : Takeda Pharmaceutical

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Guanfacine is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Prader-Willi Syndrome.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          August 26, 2019

                          Lead Product(s) : Guanfacine

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase IV

                          Sponsor : Winthrop University Hospital

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Maastricht University Medical Center

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Maastricht University Medical Center

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Details : Guanfacine HCl is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Attention Deficit Disorder with Hyperactivity.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          September 07, 2018

                          Lead Product(s) : Guanfacine

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase III

                          Sponsor : SHIRE PLC

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          UConn Health

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          UConn Health

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Details : Guanfacine is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Stress Disorders, Post-Traumatic.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          August 23, 2017

                          Lead Product(s) : Guanfacine

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase IV

                          Sponsor : SHIRE PLC | Yale University

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          New York State Psychiatric Institute

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          New York State Psychiatric Institute

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Lead Product(s) : Guanfacine

                          Therapeutic Area : Psychiatry/Psychology

                          Study Phase : Undisclosed

                          Sponsor : Columbia University | American Academy of Child Adolescent Psychiatry | SHIRE PLC

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Guanfacine is a Other Small Molecule drug candidate, which is currently being evaluated in clinical studies for the treatment of Attention Deficit Disorder with Hyperactivity.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          October 08, 2014

                          Lead Product(s) : Guanfacine

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Undisclosed

                          Sponsor : Columbia University | American Academy of Child Adolescent Psychiatry | SHIRE PLC

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          New York State Psychiatric Institute

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          New York State Psychiatric Institute

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Details : Guanfacine is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Disruptive, Impulse Control, and Conduct Disorders.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          January 29, 2014

                          Lead Product(s) : Guanfacine

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase IV

                          Sponsor : SHIRE PLC

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Yale University

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Yale University

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Lead Product(s) : Guanfacine

                          Therapeutic Area : Neurology

                          Study Phase : Phase IV

                          Sponsor : Icahn School of Medicine at Mount Sinai | University of South Florida | SHIRE PLC | New York University

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Guanfacine HCl is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Tourette Syndrome.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          March 07, 2012

                          Lead Product(s) : Guanfacine

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase IV

                          Sponsor : Icahn School of Medicine at Mount Sinai | University of South Florida | SHIRE PLC | New York University

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Intuniv (Guanfacine HCl) is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Attention Deficit Disorder with Hyperactivity.

                          Product Name : Intuniv

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          December 28, 2011

                          Lead Product(s) : Guanfacine

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Guanfacine HCl is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Anxiety Disorders.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          November 11, 2011

                          Lead Product(s) : Guanfacine

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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