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Myeloma","therapeuticArea":"Oncology","highestDevelopmentStatus":"Preclinical","country":"UNITED KINGDOM","productType":"Large molecule","productStatus":"Approved","date":"June 2024","url1":"","url2":"","graph1":"Oncology","graph2":"Preclinical"},{"orgOrder":0,"company":"GSK","sponsor":"Iteos Therapeutics","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"iTeos and GSK Launch Phase 3 Study on Belrestotug and Dostarlimab in Lung Cancer","therapeuticArea":"Oncology","highestDevelopmentStatus":"Preclinical","country":"UNITED KINGDOM","productType":"Large molecule","productStatus":"New Molecular Entity","date":"June 2024","url1":"","url2":"","graph1":"Oncology","graph2":"Preclinical"},{"orgOrder":0,"company":"GSK","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Jemperli Shows 100% No Evidence of Disease in dMMR Rectal Cancer Patients","therapeuticArea":"Oncology","highestDevelopmentStatus":"Phase II\/ Phase III","country":"UNITED KINGDOM","productType":"Large molecule","productStatus":"Approved","date":"June 2024","url1":"","url2":"","graph1":"Oncology","graph2":"Phase II\/ Phase III"},{"orgOrder":0,"company":"GSK","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"GSK\u2019s Omjjara receives Japanese approval for treatment of myelofibrosis","therapeuticArea":"Oncology","highestDevelopmentStatus":"Phase IV","country":"UNITED KINGDOM","productType":"Small molecule","productStatus":"Approved","date":"June 2024","url1":"","url2":"","graph1":"Oncology","graph2":"Phase IV"},{"orgOrder":0,"company":"GSK","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"GSK announces positive results from ph III severe asthma trials of depemokimab","therapeuticArea":"Pulmonary\/Respiratory Diseases","highestDevelopmentStatus":"Preclinical","country":"UNITED KINGDOM","productType":"Large molecule","productStatus":"New Molecular Entity","date":"May 2024","url1":"","url2":"","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Preclinical"},{"orgOrder":0,"company":"GSK","sponsor":"Elsie Biotechnologies","pharmaFlowCategory":"D","amount":"$50.0 million","upfrontCash":"Undisclosed","newsHeadline":"GSK Accelerates Oligonucleotide Platform with Acquisition of Elsie Biotechnologies","therapeuticArea":"Technology","highestDevelopmentStatus":"Discovery","country":"UNITED KINGDOM","productType":"Large molecule","productStatus":"New Molecular Entity","date":"June 2024","url1":"","url2":"","graph1":"Technology","graph2":"Discovery"}]

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            Development Status

            Details:

            Through the acquisition, Reddy will leverage the NRT portfolio, which includes Nicotinell (nicotine) in various formats such as lozenges, patches, and gum, across all applicable global market.

            Lead Product(s): Nicotine

            Therapeutic Area: Psychiatry/Psychology Product Name: Nicotinell

            Highest Development Status: Phase IV Product Type: Small molecule

            Partner/Sponsor/Collaborator: Dr. Reddy\\\'s Laboratories

            Deal Size: $632.9 million Upfront Cash: $579.8 million

            Deal Type: Acquisition June 26, 2024

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            • Development Update

            Details:

            Omjjara (momelotinib) is a once-a-day, oral JAK1/JAK2 and activin A receptor type 1 (ACVR1) inhibitor. It is indicated for the treatment of myelofibrosis.

            Lead Product(s): Momelotinib

            Therapeutic Area: Oncology Product Name: Omjjara

            Highest Development Status: Phase IV Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable June 25, 2024

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            GSK

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            • Development Update

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            Arexvy (respiratory syncytial virus vaccine, adjuvanted) is a vaccine drug candidate, which is approved for the treatment of respiratory syncytial virus disease in adults aged 50-59.

            Lead Product(s): Respiratory Syncytial Virus Vaccine, Adjuvanted

            Therapeutic Area: Infections and Infectious Diseases Product Name: Arexvy

            Highest Development Status: Phase IV Product Type: Vaccine

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable June 07, 2024

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            • Deals

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            Through acquisition, GSK to integrate Elsie’s oligonucleotide discovery, synthesis, and delivery technologies to enhance GSK’s broad oligonucleotide pipeline for difficult-to-treat diseases.

            Lead Product(s): Oligonucleotide-based Therapy

            Therapeutic Area: Technology Product Name: Undisclosed

            Highest Development Status: Discovery Product Type: Large molecule

            Recipient: Elsie Biotechnologies

            Deal Size: $50.0 million Upfront Cash: Undisclosed

            Deal Type: Acquisition June 06, 2024

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            GSK

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            • Development Update

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            Flu mRNA (GSK4382276A) is a intramuscularly administered mRNA-based multivalent seasonal influenza vaccine, which is being evaluated for the treatment of seasonal influenza.

            Lead Product(s): GSK4382276A

            Therapeutic Area: Infections and Infectious Diseases Product Name: Flu mRNA

            Highest Development Status: Phase II/ Phase III Product Type: Vaccine

            Recipient: CureVac

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable May 28, 2024

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            • Development Update

            Details:

            GSK3511294 (depemokimab) is the first ultra-long-acting biologic with a binding affinity for IL-5. It is being evaluated for the treatment of severe asthma With an eosinophilic phenotype.

            Lead Product(s): Depemokimab

            Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: GSK3511294

            Highest Development Status: Preclinical Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable May 21, 2024

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            • Deals

            Details:

            The proceeds will enable the clinical development of BioVersys’ portfolio which includes BV100 (rifabutin), a potential breakthrough hospital antibiotic with a new mode of action targeting Acinetobacter baumannii, the most drug-resistant bacterial pathogen.

            Lead Product(s): Rifabutin

            Therapeutic Area: Infections and Infectious Diseases Product Name: BV100

            Highest Development Status: Phase I/ Phase II Product Type: Small molecule

            Recipient: BioVersys AG

            Deal Size: $49.5 million Upfront Cash: Undisclosed

            Deal Type: Series C Financing May 07, 2024

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            • Deals

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            The collaboration with the GSK to accelerate the clinical development of BVL-GSK098 (alpibectir) for the treatment of tuberculosis.

            Lead Product(s): Alpibectir,Ethionamide

            Therapeutic Area: Infections and Infectious Diseases Product Name: BVL-GSK098

            Highest Development Status: Phase II/ Phase III Product Type: Small molecule

            Recipient: BioVersys AG

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Collaboration May 07, 2024

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            Details:

            UK MHRA approved two new formulations of the medicine cabotegravir (Apretude 30 mg film-coated tablets and Apretude 600 mg prolonged-release suspension for injection) to help prevent sexually transmitted HIV-1 infection in adults and adolescents.

            Lead Product(s): Cabotegravir

            Therapeutic Area: Infections and Infectious Diseases Product Name: Apretude

            Highest Development Status: Phase IV Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable May 04, 2024

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            • Development Update

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            Jemperli (dostarlimab) in combination with Zejula (niraparib) is being evaluated in phase 3 ciical trials for the treatment of primary advanced or recurrent endometrial cancer.

            Lead Product(s): Dostarlimab,Niraparib Tosylate

            Therapeutic Area: Oncology Product Name: Jemperli

            Highest Development Status: Preclinical Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable April 24, 2024

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