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Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"U.S.A","productType":"Protein","year":"2025","type":"Acquisition","leadProduct":"Efimosfermin Alpha","moa":"FGF21","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Phase II","graph3":"GSK","amount2":2,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Hepatology","amount2New":2,"dosageForm":"Subcutaneous Injection","sponsorNew":"GSK \/ GSK","highestDevelopmentStatusID":"8","companyTruncated":"GSK \/ GSK"},{"orgOrder":0,"company":"GSK","sponsor":"Iteos Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2025","type":"Inapplicable","leadProduct":"Belrestotug","moa":"||TIGIT","graph1":"Oncology","graph2":"Phase II","graph3":"GSK","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"GSK \/ GSK","highestDevelopmentStatusID":"8","companyTruncated":"GSK \/ GSK"}]

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                            Lead Product(s) : Belrestotug,Dostarlimab,Nelistotug

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Recipient : Iteos Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            iTeos Shares Interim Results of Belrestotug Combo in PD-L1+ NSCLC Patients

                            Details : GSK4057190 (dostarlimab) in combination with GSK4428859A (belrestotug) is currently being evaluated for the treatment of advanced/​metastatic non-small-cell lung cancer.

                            Product Name : GSK4428859A

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            May 13, 2025

                            Lead Product(s) : Belrestotug,Dostarlimab,Nelistotug

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Recipient : Iteos Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            GSK

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                            STLE Annual Meeting
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                            GSK

                            United Kingdom arrow
                            STLE Annual Meeting
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Belantamab Mafodotin,Bortezomib,Dexamethasone

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            GSK's Blenrep Combinations Approved by UK MHRA in Relapsed/refractory Multiple Myeloma

                            Details : Blenrep (belantamab mafodotin-blmf) is an anti-BCMA ADC. It is being evaluated in combination with pomalidomide, bortezomib and dexamethasone for the treatment of relapsed/refractory multiple myeloma.

                            Product Name : Blenrep

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            April 19, 2025

                            Lead Product(s) : Belantamab Mafodotin,Bortezomib,Dexamethasone

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            GSK

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                            STLE Annual Meeting
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                            GSK

                            United Kingdom arrow
                            STLE Annual Meeting
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Discovery Platform

                            Recipient : ABL Bio

                            Deal Size : $2,725.3 million

                            Deal Type : Licensing Agreement

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                            ABL Bio Licenses Brain Drug Platform to GSK for Neuro Diseases

                            Details : Under the licensing agreement, GSK will develop novel medicines for neurodegenerative diseases by utilizing ABL Bio's blood-brain barrier (BBB) shuttle platform, Grabody-B.

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : $49.6 million

                            April 06, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Discovery Platform

                            Recipient : ABL Bio

                            Deal Size : $2,725.3 million

                            Deal Type : Licensing Agreement

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                            04

                            GSK

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                            STLE Annual Meeting
                            Not Confirmed

                            GSK

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                            STLE Annual Meeting
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Gepotidacin

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Blujepa (Gepotidacin) FDA-Approved for Uncomplicated Urinary Tract Infections

                            Details : Blujepa (gepotidacin) is the first in a new class of oral antibiotics which inhibits topoisomerase II/IV. It is approved for the treatment of uncomplicated urinary tract infections.

                            Product Name : Blujepa

                            Product Type : Antibiotic

                            Upfront Cash : Inapplicable

                            March 25, 2025

                            Lead Product(s) : Gepotidacin

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            GSK

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                            STLE Annual Meeting
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                            GSK

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                            STLE Annual Meeting
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Mepolizumab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            EMA Reviews GSK’s Nucala Expansion for COPD Treatment

                            Details : Nucala (mepolizumab) is the first targeted anti-Interleukin-5 (IL-5) biologic. It is being investigated for the treament of COPD with an eosinophilic phenotype.

                            Product Name : Nucala

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            March 24, 2025

                            Lead Product(s) : Mepolizumab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            ViiV Healthcare

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                            STLE Annual Meeting
                            Not Confirmed

                            ViiV Healthcare

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                            STLE Annual Meeting
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : VH109,Cabotegravir

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ViiV’s N6LS Antibody Maintains Long-Acting Viral Suppression in HIV Treatment

                            Details : VH109, a CD4-binding broadly neutralising antibody, in combination with monthly cabotegravir long-acting (CAB LA), successfully kept viral levels suppressed in adults living with HIV.

                            Product Name : VH3810109

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            March 12, 2025

                            Lead Product(s) : VH109,Cabotegravir

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            GSK

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                            STLE Annual Meeting
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                            GSK

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                            STLE Annual Meeting
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                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Meningococcal Groups A, B, C, W, and Y Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            US FDA Approves GSK's Combo Meningococcal Vaccine

                            Details : Penmenvy approved for use in individuals aged 10 to 25 years. The vaccine targets 5 major serogroups of Neisseria meningitidis (A, B, C, W, & Y) which commonly cause invasive meningococcal disease.

                            Product Name : Penmenvy

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            February 15, 2025

                            Lead Product(s) : Meningococcal Groups A, B, C, W, and Y Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            GSK

                            United Kingdom arrow
                            STLE Annual Meeting
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                            GSK

                            United Kingdom arrow
                            STLE Annual Meeting
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Zoster Vaccine Recombinant, Adjuvanted

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            EMA Reviews GSK’s Shingrix New Prefilled Syringe Presentation

                            Details : Shingrix (recombinant zoster vaccine) is a non-live, recombinant subunit vaccine, being evaluated as a prefilled syringe administration for prevention of shingles in at-risk adults aged 18 and over.

                            Product Name : Shingrix

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            January 27, 2025

                            Lead Product(s) : Zoster Vaccine Recombinant, Adjuvanted

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            GSK

                            United Kingdom arrow
                            STLE Annual Meeting
                            Not Confirmed

                            GSK

                            United Kingdom arrow
                            STLE Annual Meeting
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Mepolizumab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            GSK’s Nucala Bags Another China Approval, but Biggest Test Yet to Come

                            Details : Nucala (mepolizumab) is the first targeted anti-Interleukin-5 (IL-5) biologic. It is approved as an add-on maintenance treatment for adults with chronic rhinosinusitis with nasal polyps.

                            Product Name : Nucala

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            January 03, 2025

                            Lead Product(s) : Mepolizumab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            ViiV Healthcare

                            United Kingdom arrow
                            STLE Annual Meeting
                            Not Confirmed

                            ViiV Healthcare

                            United Kingdom arrow
                            STLE Annual Meeting
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Cabotegravir,Rilpivirine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ViiV Healthcare Announces CHMP Positive Opinion for Vocabria + Rekambys HIV Treatment

                            Details : Vocabria (cabotegravir) is an HIV-1 integrase strand transfer inhibitor indicated in combnation with rilpivirine for adolescents' PrEP to reduce risk of sexually acquired HIV-1 infection.

                            Product Name : Vocabria

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 16, 2024

                            Lead Product(s) : Cabotegravir,Rilpivirine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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