
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Bretisilocin
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : AbbVie Inc
Deal Size : $1,200.0 million
Deal Type : Acquisition
AbbVie to Acquire Gilgamesh Bretisilocin, a Novel, Investigational Therapy
Details : AbbVie will GM-2505 (bretisilocin) acquire Gilgamesh's lead investigational candidate, currently in development for the treatment of patients with moderate-to-severe major depressive disorder.
Product Name : GM-2505
Product Type : Miscellaneous
Upfront Cash : Undisclosed
August 25, 2025
Lead Product(s) : Bretisilocin
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : AbbVie Inc
Deal Size : $1,200.0 million
Deal Type : Acquisition

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Lead Product(s) : Undisclosed
Therapeutic Area : Psychiatry/Psychology
Study Phase : Discovery Platform
Sponsor : AbbVie Inc
Deal Size : $2,015.0 million
Deal Type : Licensing Agreement
AbbVie and Gilgamesh Collaborate to Develop Next-Gen Therapies for Psychiatric Disorders
Details : Under terms of the license agreement, AbbVie and Gilgamesh have agreed to research and develop a portfolio of next-generation therapeutics for psychiatric disorders.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : $65.0 million
May 13, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Discovery Platform
Sponsor : AbbVie Inc
Deal Size : $2,015.0 million
Deal Type : Licensing Agreement

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Lead Product(s) : GM-1020
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Gilgamesh Announces Initiation of Phase 2a Trial of GM-1020 in Major Depressive Disorder
Details : GM-1020 is a novel, orally bioavailable NMDA receptor antagonist with reduced sedative and dissociative side effects. It is being evaluated for the treatment of major depressive disorder.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 01, 2024
Lead Product(s) : GM-1020
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Ibogaine
Therapeutic Area : Psychiatry/Psychology
Study Phase : Preclinical
Sponsor : National Institute on Drug Abuse
Deal Size : Undisclosed
Deal Type : Funding
Gilgamesh Awarded $14M Grant for Cardiac-Safe Ibogaine Analog in Opioid Use Disorder
Details : The funding aims to support the company's ongoing development of GM-3009 (ibogaine), a Kappa opioid receptor agonist. It is evaluated in the Preclinical trials for Opioid-Related Disorders.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
March 14, 2024
Lead Product(s) : Ibogaine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Preclinical
Sponsor : National Institute on Drug Abuse
Deal Size : Undisclosed
Deal Type : Funding

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Lead Product(s) : GM-1020
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Clinical Study to Evaluate of Single and Multiple Oral Doses of GM-1020 in Patients With MDD
Details : GM-1020 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Depressive Disorder, Major.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 13, 2024
Lead Product(s) : GM-1020
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : GM-2505
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Phase 2a Study to Evaluate the Safety and Tolerability of GM-2505 in Patients With MDD
Details : GM-2505 is a drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Depressive Disorder, Major.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
February 01, 2024
Lead Product(s) : GM-2505
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : GM-1020
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Gilgamesh Pharmaceuticals Successfully Completes Phase 1 SAD/MAD Clinical Trials of GM-1020
Details : GM-1020 is a novel, oral NMDA receptor antagonist with the potential of advancing a new treatment option for patients with major depressive disorders and other neuropsychiatric conditions.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 21, 2023
Lead Product(s) : GM-1020
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : GM-1020
Therapeutic Area : Psychiatry/Psychology
Study Phase : Preclinical
Sponsor : Prime Movers Lab
Deal Size : $39.0 million
Deal Type : Series B Financing
Gilgamesh Pharmaceuticals Raises $39 Million Series B to Advance Mental Health Treatments
Details : GM-1020 is a novel, patented (composition of matter), orally active small molecule antagonist of the N-methyl-D-aspartate (NMDA) receptor with the potential to have rapid-acting antidepressant (RAAD) activity without adverse behavioral effects at therape...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
December 15, 2022
Lead Product(s) : GM-1020
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Preclinical
Sponsor : Prime Movers Lab
Deal Size : $39.0 million
Deal Type : Series B Financing
