Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Geron Wins EU Approval for RYTELO (imetelstat) in Lower-Risk MDS Anemia
Details : Rytelo (imetelstat) is an investigational, novel telomerase inhibitor, administered via intravenous infusion, indicated for transfusion-dependent anemia due to lower-risk MDS.
Product Name : Rytelo
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
March 11, 2025
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Geron Secures CHMP Opinion for RYTELO™ for Transfusion-Dependent Anemia in MDS
Details : Rytelo (imetelstat) is an investigational, novel telomerase inhibitor, administered via intravenous infusion, indicated for transfusion-dependent anemia due to lower-risk MDS.
Product Name : Rytelo
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
December 13, 2024
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Royalty Pharma
Deal Size : $250.0 million
Deal Type : Financing
Geron Secures up to $375M Funding from Royalty Pharma & Pharmakon Advisors
Details : The proceeds will support the commercial launch of Rytelo (imetelstat), a first-in-class treatment that works by inhibiting telomerase enzymatic activity, in the U.S. and potential launch in the EU.
Product Name : Rytelo
Product Type : Oligonucleotide
Upfront Cash : $250.0 million
July 11, 2024
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Royalty Pharma
Deal Size : $250.0 million
Deal Type : Financing
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Geron's RYTELO Approved by FDA for Low-Risk MDS with Transfusion-Dependent Anemia
Details : Rytelo (imetelstat) is an investigational, novel telomerase inhibitor, administered via intravenous infusion, being developed for relapsed/refractory myelofibrosis.
Product Name : Rytelo
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
June 06, 2024
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : TD Cowen
Deal Size : $150.0 million
Deal Type : Public Offering
Geron Corporation Announces Pricing Of $150 Million Underwritten Offering
Details : Geron plans to fund commercialization of GRN163L and potential launch of imetelstat for low/intermediate-1 risk myelodysplastic syndromes in the U.S. and EU.
Product Name : Rytelo
Product Type : Oligonucleotide
Upfront Cash : Undisclosed
March 19, 2024
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : TD Cowen
Deal Size : $150.0 million
Deal Type : Public Offering
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : GRN163L (imetelstat) is an investigational, novel telomerase inhibitor, by which drug inhibits the uncontrolled proliferation of malignant stem and progenitor cells in myeloid hematologic malignancies resulting in malignant cell apoptosis.
Product Name : Rytelo
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
November 01, 2023
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Goldman Sachs & Co
Deal Size : $227.8 million
Deal Type : Public Offering
Details : Geron currently intends to use the net proceeds from this public offering to fund preparatory activities for the potential U.S. commercial launch of GRN163L (imetelstat) in lower risk MDS, and, if approved, to fund the potential U.S. commercial launch of...
Product Name : Rytelo
Product Type : Oligonucleotide
Upfront Cash : Undisclosed
October 01, 2023
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Goldman Sachs & Co
Deal Size : $227.8 million
Deal Type : Public Offering
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : GRN163L (imetelstat) is an investigational, novel telomerase inhibitor, by which drug inhibits the uncontrolled proliferation of malignant stem and progenitor cells in relapsed/refractory AML or higher risk MDS resulting in malignant cell apoptosis.
Product Name : Rytelo
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
September 29, 2023
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Geron Announces PDUFA Date for Imetelstat NDA in Lower Risk MDS
Details : GRN163L (imetelstat) is an investigational, novel telomerase inhibitor, by which drug inhibits the uncontrolled proliferation of malignant stem and progenitor cells in Relapsed/Refractory AML or Higher Risk MDS resulting in malignant cell apoptosis.
Product Name : Rytelo
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
August 22, 2023
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : GRN163L (imetelstat) is an investigational, novel telomerase inhibitor, by which drug inhibits the uncontrolled proliferation of malignant stem and progenitor cells in relapsed/refractory AML or higher risk MDS resulting in malignant cell apoptosis.
Product Name : Rytelo
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
August 21, 2023
Lead Product(s) : Imetelstat
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable