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    [{"orgOrder":0,"company":"Minovia Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"ISRAEL","productType":"Cell and Gene therapy","year":"2025","type":"Inapplicable","leadProduct":"MNV-201","moa":"Undisclosed","graph1":"Genetic Disease","graph2":"Phase I","graph3":"Minovia Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Minovia Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Minovia Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"BioLineRx","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"ISRAEL","productType":"Peptide","year":"2023","type":"Inapplicable","leadProduct":"Motixafortide","moa":"||CXCR-4 receptor","graph1":"Genetic Disease","graph2":"Phase I","graph3":"BioLineRx","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"BioLineRx \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"BioLineRx \/ Inapplicable"},{"orgOrder":0,"company":"BioLineRx","sponsor":"St. Jude Children\u2019s Research Hospital","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"ISRAEL","productType":"Peptide","year":"2024","type":"Agreement","leadProduct":"Motixafortide","moa":"CXCR-4 receptor","graph1":"Genetic Disease","graph2":"Phase I","graph3":"BioLineRx","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"BioLineRx \/ St. Jude Children\u2019s Research Hospital","highestDevelopmentStatusID":"6","companyTruncated":"BioLineRx \/ St. Jude Children\u2019s Research Hospital"},{"orgOrder":0,"company":"BioLineRx","sponsor":"Washington University School of Medicine","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"ISRAEL","productType":"Peptide","year":"2023","type":"Collaboration","leadProduct":"Motixafortide","moa":"||CXCR-4 receptor","graph1":"Genetic Disease","graph2":"Phase I","graph3":"BioLineRx","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"BioLineRx \/ Washington University School of Medicine","highestDevelopmentStatusID":"6","companyTruncated":"BioLineRx \/ Washington University School of Medicine"}]

    Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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                            01

                            Minovia Therapeutics

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                            Minovia Therapeutics

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                            Lead Product(s) : MNV-201

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Minovia Gets FDA Nod for Phase II Trial of MNV-201 in Pearson Syndrome

                            Details : MNV-201, an autologous hematopoietic stem cell product augmented with allogeneic mitochondria. It is being evaluated for the treatment of pearson syndrome.

                            Product Name : MNV-201

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            April 03, 2025

                            Lead Product(s) : MNV-201

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            BioLineRx

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                            Indo Livestock Expo
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                            BioLineRx

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                            Lead Product(s) : Motixafortide

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I

                            Sponsor : St. Jude Children’s Research Hospital

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            BioLineRx and St. Jude Evaluate Motixafortide for CD34+ HSC Mobilization

                            Details : The agreement aims to evaluate motixafortide for the mobilization of CD34+ hematopoietic stem cells (HSCs) used in the development of gene therapies for patients with sickle cell disease (SCD).

                            Product Name : Aphexda

                            Product Type : Peptide

                            Upfront Cash : Undisclosed

                            May 30, 2024

                            Lead Product(s) : Motixafortide

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I

                            Sponsor : St. Jude Children’s Research Hospital

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            03

                            SpliSense

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                            SpliSense

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                            Lead Product(s) : SPL84

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I

                            Sponsor : Cystic Fibrosis Foundation

                            Deal Size : $8.5 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            CF Foundation Provides Up to $8.5M to SpliSense for Splicing Mutation Treatment Trial

                            Details : The funding will support SpliSense to continue the clinical development of an inhaled antisense oligonucleotide drug SPL84 for treating patients suffering from cystic fibrosis.

                            Product Name : SPL84

                            Product Type : Oligonucleotide

                            Upfront Cash : Undisclosed

                            March 04, 2024

                            Lead Product(s) : SPL84

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I

                            Sponsor : Cystic Fibrosis Foundation

                            Deal Size : $8.5 million

                            Deal Type : Funding

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                            04

                            SpliSense

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                            SpliSense

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                            Lead Product(s) : SPL84

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            SpliSense Announces FDA Clearance for SPL84 Phase 2 Initiation for Cystic Fibrosis

                            Details : SPL84 is an antisense oligonucleotide product that binds specifically to the mutated CFTR RNA in the targeted sequence. It is being evaluated for the treatment of cystic fibrosis.

                            Product Name : SPL84

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            March 04, 2024

                            Lead Product(s) : SPL84

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            BioLineRx

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                            BioLineRx

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                            Lead Product(s) : Motixafortide,Natalizumab

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            BioLineRx Announces First Patient Dosed in Phase 1 Clinical Trial Evaluating Motixafortide for CD34+ Hematopoi...

                            Details : BioLineRx initiated Phase I clinical trial studies evaluating BL-8040 (motixafortide), CXCR4/SDF-1 inhibitor, as monotherapy and in combination with natalizumab for the treatment of sickle cell disease.

                            Product Name : Aphexda

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            December 21, 2023

                            Lead Product(s) : Motixafortide,Natalizumab

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            SpliSense

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                            Lead Product(s) : SPL84

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            SpliSense Successfully Completed Phase 1 Study of SPL84, RNA-Based Therapy, for the Treatment of Cystic Fibros...

                            Details : SPL84, the Company's lead inhaled anti sense oligonucleotide (ASO) product for the treatment of patients with CF, carrying the 3849+10 kilobase (Kb) C->T splicing mutation in the transmembrane conductance regulator (CFTR) gene.

                            Product Name : SPL84

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            June 09, 2023

                            Lead Product(s) : SPL84

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            BioLineRx

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                            BioLineRx

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                            Lead Product(s) : Motixafortide,Natalizumab

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I

                            Sponsor : Washington University School of Medicine

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            BioLineRx Announces Clinical Trial Collaboration with Washington University School of Medicine to Evaluate Mot...

                            Details : The aim of the collaboration is to advance a Phase 1 clinical trial that will evaluate the safety and feasibility of BL-8040 (motixafortide) to mobilize CD34+ hematopoietic stem cells (HSCs) for gene therapies in sickle cell disease (SCD).

                            Product Name : Aphexda

                            Product Type : Peptide

                            Upfront Cash : Undisclosed

                            June 03, 2023

                            Lead Product(s) : Motixafortide,Natalizumab

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I

                            Sponsor : Washington University School of Medicine

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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