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              F. Hoffmann-La Roche

              • Development Update

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              SWITZERLAND Switzerland

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              Pharma Industry and Pharmaceuticals

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              Roche Writes Off Ulcerative Colitis Portion of Etrolizumab Program, Days After Dissecting Phase III Setback

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              Lead Product(s): Etrolizumab,Adalimumab

              Therapeutic Area: Gastroenterology Product Name: RG7413

              Highest Development Status: Phase III Product Type: Large molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable October 15, 2020

              Details:

              After disappointing Phase III results Roche has decided to discontinue etrolizumab program as an ulcerative colitis treatment. The drug failed meet its primary endpoint compared to Remicade.

              F. Hoffmann-La Roche

              • Development Update

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              SWITZERLAND Switzerland

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              Roche Provides Update on Phase III Studies of Etrolizumab In People with Moderately to Severely Active Ulcerative Colitis

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              Lead Product(s): Etrolizumab,Adalimumab

              Therapeutic Area: Gastroenterology Product Name: RG7413

              Highest Development Status: Phase III Product Type: Large molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable August 10, 2020

              Details:

              Etrolizumab met its primary endpoint of inducing remission versus placebo for people with ulcerative colitis in only two of three studies.

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