Drugs in Dev.
Gastroenterology
Phase II
United Kingdom 
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Lead Product(s) : AltSonflex1-2-3,MR-VAC
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Bharat Biotech
Deal Size : Undisclosed
Deal Type : Licensing Agreement
GSK Licenses Shigella Vaccine Candidate to Bharat Biotech for Continued Development
Details : The agreement paves the way for the ongoing development and potential distribution of the shigella vaccine candidate, altSonflex1-2-3, in low-and-middle income countries.
Product Name : AltSonflex1-2-3
Product Type : Vaccine
Upfront Cash : Undisclosed
June 12, 2025
Lead Product(s) : AltSonflex1-2-3,MR-VAC
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Bharat Biotech
Deal Size : Undisclosed
Deal Type : Licensing Agreement

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Lead Product(s) : EBX-102-02
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
EnteroBiotix Reports Positive Phase 2a Results for EBX-102-02 in IBS
Details : EBX-102-02, the company’s next-generation full-spectrum microbiome product, currently under clinical trials in adults with irritable bowel syndrome with constipation (IBS-C).
Product Name : Undisclosed
Product Type : Probiotic
Upfront Cash : Inapplicable
March 18, 2025
Lead Product(s) : EBX-102-02
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : EBX-102-02
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
EnteroBiotix Completes Phase 2 Study Recruitment of EBX-102-02 in Irritable Bowel Syndrome
Details : EBX-102-02 is a next-generation, full-spectrum drug candidate that restore and fortify the microbiome. It is being evaluated for irritable bowel syndrome.
Product Name : Undisclosed
Product Type : Probiotic
Upfront Cash : Inapplicable
November 18, 2024
Lead Product(s) : EBX-102-02
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Altsonflex
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Altsonflex is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Diarrhea.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 29, 2024
Lead Product(s) : Altsonflex
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : EBX-102-02
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Thairm Bio
Deal Size : $34.0 million
Deal Type : Financing
EnteroBiotix Completes £27m Financing Round to Advance Clinical Trials
Details : The net proceeds will advance EBX’s lead candidate, EBX-102-02, a next-generation drug with diverse microbial ecosystems, through a Phase 2 trial in Irritable Bowel Syndrome.
Product Name : Undisclosed
Product Type : Probiotic
Upfront Cash : Undisclosed
April 04, 2024
Lead Product(s) : EBX-102-02
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Thairm Bio
Deal Size : $34.0 million
Deal Type : Financing

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Lead Product(s) : EBX-102-02
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
EnteroBiotix Initiates Phase 2 Study of EBX-102-02 for Irritable Bowel Syndrome
Details : EBX-102-02 is a next-gen drug candidate with diverse microbial ecosystems, evaluated for restoring the microbiome in patients with irritable bowel syndrome.
Product Name : Undisclosed
Product Type : Probiotic
Upfront Cash : Inapplicable
April 03, 2024
Lead Product(s) : EBX-102-02
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Blautia Hydrogenotrophica
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Results demonstrate changes in gut microbiome structure following administration of Blautix (Blautia Hydrogenotrophica) in both IBS-C and IBS-D patients.
Product Name : Blautix
Product Type : Microorganism
Upfront Cash : Inapplicable
December 09, 2021
Lead Product(s) : Blautia Hydrogenotrophica
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Blautia Hydrogenotrophica
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
4D pharma to Present Additional Data from Phase II Study of Blautix for Irritable Bowel Syndrome
Details : In Phase II trial, where Blautix demonstrated signals of clinical activity in both IBS-C and IBS-D, and a highly favorable safety and tolerability profile.
Product Name : Blautix
Product Type : Microorganism
Upfront Cash : Inapplicable
May 17, 2021
Lead Product(s) : Blautia Hydrogenotrophica
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Blautia Hydrogenotrophica
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The phase II trial showed that Blautix treatment resulted in: A statistically significant increase in overall response in pre-planned analysis of the combined IBS-C/D group compared to placebo; A positive, increase in overall response in both IBS-C and I...
Product Name : Blautix
Product Type : Microorganism
Upfront Cash : Inapplicable
October 07, 2020
Lead Product(s) : Blautia Hydrogenotrophica
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : CJRB 205,Blautia Hydrogenotrophica
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Trial for New Treatment of Adult Participants With Irritable Bowel Syndrome
Details : Blautix (CJRB 205) is a drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Irritable Bowel Syndrome.
Product Name : Blautix
Product Type : Microorganism
Upfront Cash : Inapplicable
October 26, 2018
Lead Product(s) : CJRB 205,Blautia Hydrogenotrophica
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
