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    [{"orgOrder":0,"company":"GSK","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"UNITED KINGDOM","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Altsonflex","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Phase II","graph3":"GSK","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"GSK \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"GSK \/ Inapplicable"},{"orgOrder":0,"company":"GSK","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"UNITED KINGDOM","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Altsonflex","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Phase II","graph3":"GSK","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"GSK \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"GSK \/ Inapplicable"},{"orgOrder":0,"company":"4D Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"UNITED KINGDOM","productType":"Microorganism","year":"2021","type":"Inapplicable","leadProduct":"Blautia Hydrogenotrophica","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Phase II","graph3":"4D Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"4D Pharma \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"4D Pharma \/ Inapplicable"},{"orgOrder":0,"company":"4D Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"UNITED KINGDOM","productType":"Microorganism","year":"2021","type":"Inapplicable","leadProduct":"Blautia Hydrogenotrophica","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Phase II","graph3":"4D Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"4D Pharma \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"4D Pharma \/ Inapplicable"},{"orgOrder":0,"company":"4D Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"UNITED KINGDOM","productType":"Microorganism","year":"2020","type":"Inapplicable","leadProduct":"Blautia Hydrogenotrophica","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Phase II","graph3":"4D Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"4D Pharma \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"4D Pharma \/ Inapplicable"},{"orgOrder":0,"company":"EnteroBiotix","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"UNITED KINGDOM","productType":"Probiotic","year":"2024","type":"Inapplicable","leadProduct":"EBX-102-02","moa":"Gut microbiome","graph1":"Gastroenterology","graph2":"Phase II","graph3":"EnteroBiotix","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"EnteroBiotix \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"EnteroBiotix \/ Inapplicable"},{"orgOrder":0,"company":"EnteroBiotix","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"UNITED KINGDOM","productType":"Probiotic","year":"2024","type":"Inapplicable","leadProduct":"EBX-102-02","moa":"Gut microbiome","graph1":"Gastroenterology","graph2":"Phase II","graph3":"EnteroBiotix","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"EnteroBiotix \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"EnteroBiotix \/ Inapplicable"},{"orgOrder":0,"company":"EnteroBiotix","sponsor":"Thairm Bio","pharmaFlowCategory":"D","therapeuticArea":"Gastroenterology","country":"UNITED KINGDOM","productType":"Probiotic","year":"2024","type":"Financing","leadProduct":"EBX-102-02","moa":"Gut microbiome","graph1":"Gastroenterology","graph2":"Phase II","graph3":"EnteroBiotix","amount2":0.029999999999999999,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0.029999999999999999,"dosageForm":"Capsule","sponsorNew":"EnteroBiotix \/ Thairm Bio","highestDevelopmentStatusID":"8","companyTruncated":"EnteroBiotix \/ Thairm Bio"},{"orgOrder":0,"company":"EnteroBiotix","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"UNITED KINGDOM","productType":"Probiotic","year":"2025","type":"Inapplicable","leadProduct":"EBX-102-02","moa":"Gut microbiome","graph1":"Gastroenterology","graph2":"Phase II","graph3":"EnteroBiotix","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"EnteroBiotix \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"EnteroBiotix \/ Inapplicable"},{"orgOrder":0,"company":"GSK","sponsor":"Bharat Biotech","pharmaFlowCategory":"D","therapeuticArea":"Gastroenterology","country":"UNITED KINGDOM","productType":"Vaccine","year":"2025","type":"Licensing Agreement","leadProduct":"AltSonflex1-2-3","moa":"||Undisclosed","graph1":"Gastroenterology","graph2":"Phase II","graph3":"GSK","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Injection","sponsorNew":"GSK \/ Bharat Biotech","highestDevelopmentStatusID":"8","companyTruncated":"GSK \/ Bharat Biotech"}]

    Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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                            01

                            GSK

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                            Lead Product(s) : AltSonflex1-2-3,MR-VAC

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Bharat Biotech

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            GSK Licenses Shigella Vaccine Candidate to Bharat Biotech for Continued Development

                            Details : The agreement paves the way for the ongoing development and potential distribution of the shigella vaccine candidate, altSonflex1-2-3, in low-and-middle income countries.

                            Product Name : AltSonflex1-2-3

                            Product Type : Vaccine

                            Upfront Cash : Undisclosed

                            June 12, 2025

                            Lead Product(s) : AltSonflex1-2-3,MR-VAC

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Bharat Biotech

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            02

                            EnteroBiotix

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                            Lead Product(s) : EBX-102-02

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            EnteroBiotix Reports Positive Phase 2a Results for EBX-102-02 in IBS

                            Details : EBX-102-02, the company’s next-generation full-spectrum microbiome product, currently under clinical trials in adults with irritable bowel syndrome with constipation (IBS-C).

                            Product Name : Undisclosed

                            Product Type : Probiotic

                            Upfront Cash : Inapplicable

                            March 18, 2025

                            Lead Product(s) : EBX-102-02

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            EnteroBiotix

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                            Lead Product(s) : EBX-102-02

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            EnteroBiotix Completes Phase 2 Study Recruitment of EBX-102-02 in Irritable Bowel Syndrome

                            Details : EBX-102-02 is a next-generation, full-spectrum drug candidate that restore and fortify the microbiome. It is being evaluated for irritable bowel syndrome.

                            Product Name : Undisclosed

                            Product Type : Probiotic

                            Upfront Cash : Inapplicable

                            November 18, 2024

                            Lead Product(s) : EBX-102-02

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            GSK

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                            Lead Product(s) : Altsonflex

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study on the Immune Response and Safety of a Multicomponent Shigella Vaccine in Preventing Shigellosis in In...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 29, 2024

                            Lead Product(s) : Altsonflex

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            EnteroBiotix

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                            Lead Product(s) : EBX-102-02

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Thairm Bio

                            Deal Size : $34.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            EnteroBiotix Completes £27m Financing Round to Advance Clinical Trials

                            Details : The net proceeds will advance EBX’s lead candidate, EBX-102-02, a next-generation drug with diverse microbial ecosystems, through a Phase 2 trial in Irritable Bowel Syndrome.

                            Product Name : Undisclosed

                            Product Type : Probiotic

                            Upfront Cash : Undisclosed

                            April 04, 2024

                            Lead Product(s) : EBX-102-02

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Thairm Bio

                            Deal Size : $34.0 million

                            Deal Type : Financing

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                            EnteroBiotix

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                            Lead Product(s) : EBX-102-02

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            EnteroBiotix Initiates Phase 2 Study of EBX-102-02 for Irritable Bowel Syndrome

                            Details : EBX-102-02 is a next-gen drug candidate with diverse microbial ecosystems, evaluated for restoring the microbiome in patients with irritable bowel syndrome.

                            Product Name : Undisclosed

                            Product Type : Probiotic

                            Upfront Cash : Inapplicable

                            March 04, 2024

                            Lead Product(s) : EBX-102-02

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            4D Pharma

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                            Lead Product(s) : Blautia Hydrogenotrophica

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            4D Pharma Presents Microbiome Analyses from Phase II Clinical Trial of Blautix® for IBS-C and IBS-D at Gastro...

                            Details : Results demonstrate changes in gut microbiome structure following administration of Blautix (Blautia Hydrogenotrophica) in both IBS-C and IBS-D patients.

                            Product Name : Blautix

                            Product Type : Microorganism

                            Upfront Cash : Inapplicable

                            September 12, 2021

                            Lead Product(s) : Blautia Hydrogenotrophica

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            4D Pharma

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                            Lead Product(s) : Blautia Hydrogenotrophica

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            4D pharma to Present Additional Data from Phase II Study of Blautix for Irritable Bowel Syndrome

                            Details : In Phase II trial, where Blautix demonstrated signals of clinical activity in both IBS-C and IBS-D, and a highly favorable safety and tolerability profile.

                            Product Name : Blautix

                            Product Type : Microorganism

                            Upfront Cash : Inapplicable

                            May 17, 2021

                            Lead Product(s) : Blautia Hydrogenotrophica

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            4D Pharma

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                            Lead Product(s) : Blautia Hydrogenotrophica

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            4D Pharma Announces Positive Results from Phase II BHT-II-002 Trial of Blautix in Irritable Bowel Syndrome

                            Details : The phase II trial showed that Blautix treatment resulted in: A statistically significant increase in overall response in pre-planned analysis of the combined IBS-C/D group compared to placebo; A positive, increase in overall response in both IBS-C and I...

                            Product Name : Blautix

                            Product Type : Microorganism

                            Upfront Cash : Inapplicable

                            July 10, 2020

                            Lead Product(s) : Blautia Hydrogenotrophica

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            4D Pharma

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                            Lead Product(s) : CJRB 205

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Trial for New Treatment of Adult Participants With Irritable Bowel Syndrome

                            Details : Undisclosed

                            Product Name : Blautix

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            October 26, 2018

                            Lead Product(s) : CJRB 205

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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