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Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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                          Top Deals by Deal Size (USD bn)

                          01

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : EBX-102-02, the company’s next-generation full-spectrum microbiome product, currently under clinical trials in adults with irritable bowel syndrome with constipation (IBS-C).

                          Product Name : EBX-102-02

                          Product Type : Probiotic

                          Upfront Cash : Inapplicable

                          March 18, 2025

                          Lead Product(s) : EBX-102-02

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : EBX-102-02 is a next-generation, full-spectrum drug candidate that restore and fortify the microbiome. It is being evaluated for irritable bowel syndrome.

                          Product Name : EBX-102-02

                          Product Type : Probiotic

                          Upfront Cash : Inapplicable

                          November 18, 2024

                          Lead Product(s) : EBX-102-02

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : The net proceeds will advance EBX’s lead candidate, EBX-102-02, a next-generation drug with diverse microbial ecosystems, through a Phase 2 trial in Irritable Bowel Syndrome.

                          Product Name : EBX-102-02

                          Product Type : Probiotic

                          Upfront Cash : Undisclosed

                          April 04, 2024

                          Lead Product(s) : EBX-102-02

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : Thairm Bio

                          Deal Size : $34.0 million

                          Deal Type : Financing

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                          04

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : EBX-102-02 is a next-gen drug candidate with diverse microbial ecosystems, evaluated for restoring the microbiome in patients with irritable bowel syndrome.

                          Product Name : EBX-102-02

                          Product Type : Probiotic

                          Upfront Cash : Inapplicable

                          March 04, 2024

                          Lead Product(s) : EBX-102-02

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : Results demonstrate changes in gut microbiome structure following administration of Blautix (Blautia Hydrogenotrophica) in both IBS-C and IBS-D patients.

                          Product Name : Blautix

                          Product Type : Microorganism

                          Upfront Cash : Inapplicable

                          September 12, 2021

                          Lead Product(s) : Blautia Hydrogenotrophica

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : In Phase II trial, where Blautix demonstrated signals of clinical activity in both IBS-C and IBS-D, and a highly favorable safety and tolerability profile.

                          Product Name : Blautix

                          Product Type : Microorganism

                          Upfront Cash : Inapplicable

                          May 17, 2021

                          Lead Product(s) : Blautia Hydrogenotrophica

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          IFT FIRST
                          Not Confirmed
                          IFT FIRST
                          Not Confirmed

                          Details : The phase II trial showed that Blautix treatment resulted in: A statistically significant increase in overall response in pre-planned analysis of the combined IBS-C/D group compared to placebo; A positive, increase in overall response in both IBS-C and I...

                          Product Name : Blautix

                          Product Type : Microorganism

                          Upfront Cash : Inapplicable

                          July 10, 2020

                          Lead Product(s) : Blautia Hydrogenotrophica

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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