 Drugs in Dev.
 Drugs in Dev.								 Gastroenterology
Gastroenterology
											 Phase II
Phase II
											
																			 Sweden
Sweden								
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Lead Product(s) : Bupivacaine
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : University of California
Deal Size : Undisclosed
Deal Type : Collaboration
OncoZenge Enters into Collaboration with UCLA for Patient Engagement Study on BupiZenge
Details : The partnership focuses on a patient engagement study in managing oral mucositis pain, while exploring potential pathways toward a future IND application for BupiZenge.
Product Name : BupiZenge
Product Type : Miscellaneous
Upfront Cash : Undisclosed
September 17, 2025
Lead Product(s) : Bupivacaine
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : University of California
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Linaprazan Glurate
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Zentiva
Deal Size : $249.2 million
Deal Type : Licensing Agreement
Zentiva Inks €220M Deal for Former AstraZeneca GI Drug in Europe
Details : Under the licensing agreement, Zentiva will hold the rights for the commercialization and manufacturing of linaprazan glurate, in Europe.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : $14.7 million
May 22, 2025
Lead Product(s) : Linaprazan Glurate
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Zentiva
Deal Size : $249.2 million
Deal Type : Licensing Agreement

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Lead Product(s) : Lactobacillus Reuteri
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
The Connection Study Continues After Pre-scheduled Data Monitoring Committee (DMC) Review
Details : IBP-9414 (lactobacillus Reuteri), strain-specific attributes which affect the NEC pathogenesis is world’s first approved probiotic drug with the goal to prevent life-threatening diseases in premature infants.
Product Name : Undisclosed
Product Type : Probiotic
Upfront Cash : Inapplicable
January 19, 2022
Lead Product(s) : Lactobacillus Reuteri
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lactobacillus gasseri BGP345A
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : BioFortis
Deal Size : Inapplicable
Deal Type : Inapplicable
Safety and Preliminary Efficacy of BGP345A in Constipation Due to Opioid-based Medications
Details : Lactobacillus gasseri BGP345A is a drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Opioid-Induced Constipation.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
November 24, 2021
Lead Product(s) : Lactobacillus gasseri BGP345A
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : BioFortis
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : X842
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Parexel
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : X842 is a drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Esophagitis.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
September 24, 2021
Lead Product(s) : X842
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Parexel
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lactobacillus Reuteri
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : IBT is developing the drug candidate IBP-9414, contains the active substance Lactobacillus reuteri, which is a human bacterial strain naturally present in breast milk, for the prevention of necrotizing enterocolitis and improvement of feeding tolerance i...
Product Name : Undisclosed
Product Type : Probiotic
Upfront Cash : Inapplicable
April 29, 2021
Lead Product(s) : Lactobacillus Reuteri
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Lactobacillus Reuteri
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Infant Bacterial Therapeutics AB (publ) Interim Management Statement, January 1 – December 31, 2020
Details : IBT is currently developing IBP-9414 to prevent necrotizing enterocolitis, and to improve feeding tolerance in premature infants. IBP-9414 contains Lactobacillus reuteri as an active ingredient, which is a human bacterial strain found naturally in breast...
Product Name : Undisclosed
Product Type : Probiotic
Upfront Cash : Inapplicable
February 05, 2021
Lead Product(s) : Lactobacillus Reuteri
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Linaprazan Glurate
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Fourth Swedish National Pension Fund
Deal Size : $25.6 million
Deal Type : Financing
Details : The proceeds from the financing round will be used to perform a phase 2 clinical trial, which is expected to start in the second half of 2020.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
March 04, 2020
Lead Product(s) : Linaprazan Glurate
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Fourth Swedish National Pension Fund
Deal Size : $25.6 million
Deal Type : Financing

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Lead Product(s) : Tetravalent Etec Vaccine
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Göteborg University | United Medix Laboratories Ltd. | Medfiles Ltd | University of Helsinki | University of Virginia
Deal Size : Inapplicable
Deal Type : Inapplicable
Prevention of Diarrheal Disease Due to Infection With Enterotoxigenic E. Coli (ETEC)
Details : Tetravalent Etec Vaccine is a Vaccine drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Diarrhea.
Product Name : Undisclosed
Product Type : Vaccine
Upfront Cash : Inapplicable
November 02, 2018
Lead Product(s) : Tetravalent Etec Vaccine
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Göteborg University | United Medix Laboratories Ltd. | Medfiles Ltd | University of Helsinki | University of Virginia
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : IBP-9414
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
IBP-9414 for the Prevention of Necrotizing Enterocolitis
Details : IBP-9414 is a Probiotic drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Enterocolitis, Necrotizing.
Product Name : Undisclosed
Product Type : Probiotic
Upfront Cash : Inapplicable
June 16, 2015
Lead Product(s) : IBP-9414
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable


 
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