Lead Product(s) : SL-325
Therapeutic Area : Gastroenterology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : $103.0 million
Deal Type : Private Placement
Shattuck Labs Announces Closing of up to $103 Million Private Placement
Details : The proceeds from the financing will be used to advance SL-325 through multiple clinical milestones. Currently it is being evluated for the treatment of Inflammatory Bowel Disease.
Product Name : SL-325
Product Type : Antibody
Upfront Cash : Undisclosed
August 26, 2025
Lead Product(s) : SL-325
Therapeutic Area : Gastroenterology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : $103.0 million
Deal Type : Private Placement
Lead Product(s) : NEU-001
Therapeutic Area : Gastroenterology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
FDA Grants Orphan & Rare Pediatric Status to Neurenati’s NEU-001 for Hirschsprung
Details : NEU-001 is a first-in-class, once-in-a-lifetime treatment administered intrarectally, which is being evaluated to treat Hirschsprung's disease.
Product Name : Undisclosed
Product Type : Protein
Upfront Cash : Inapplicable
March 04, 2025
Lead Product(s) : NEU-001
Therapeutic Area : Gastroenterology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : SL-325
Therapeutic Area : Gastroenterology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Shattuck Labs Shares Positive Data on SL-325 in IBD at ECCO 2025
Details : SL-325 is a first-in-class DR3 antagonist, currently being investigated for the treatment of inflammatory bowel diseases.
Product Name : Undisclosed
Product Type : Antibody
Upfront Cash : Inapplicable
February 20, 2025
Lead Product(s) : SL-325
Therapeutic Area : Gastroenterology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : SL-325
Therapeutic Area : Gastroenterology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Shattuck Labs Announces SL-325, a First-In-Class DR3 Antagonist, in TL1A/DR3 Pathway
Details : SL-325 is a first-in-class antagonist antibody to DR3, the receptor for TL1A, which is being evaluated for the treatment of inflammatory bowel disease.
Product Name : Undisclosed
Product Type : Antibody
Upfront Cash : Inapplicable
January 10, 2024
Lead Product(s) : SL-325
Therapeutic Area : Gastroenterology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Naronapride
Therapeutic Area : Gastroenterology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Naronapride possess both serotonin 5HT4 receptor agonistic and dopamine D2 receptor antagonistic properties. It is currently being investigaetd for chronic idiopathic constipation (CIC) and gastro-esophageal reflux disease (GERD).
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 01, 2023
Lead Product(s) : Naronapride
Therapeutic Area : Gastroenterology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : CampETEC
Therapeutic Area : Gastroenterology
Study Phase : IND Enabling
Sponsor : Immuron
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CampETEC is a new therapeutic developed in collaboration with NMRC. Two Phase Il clinical studies are planned to evaluate safety and clinical efficacy against infectious diarrhea caused by Campylobacter and ETEC.
Product Name : CampETEC
Product Type : Vaccine
Upfront Cash : Inapplicable
August 05, 2023
Lead Product(s) : CampETEC
Therapeutic Area : Gastroenterology
Highest Development Status : IND Enabling
Sponsor : Immuron
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : OQL051
Therapeutic Area : Gastroenterology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : OQL051 sia first-in-disease, oral, gut-restricted CDK4/6 inhibitor – is designed to prevent the development of CID in patients receiving cytotoxic chemotherapies. The drug works by temporarily arresting the rapidly dividing intestinal mucosal cells in ...
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 06, 2023
Lead Product(s) : OQL051
Therapeutic Area : Gastroenterology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Psilocybine
Therapeutic Area : Gastroenterology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : TRP-8802 (Oral psilocybin) in patients with Irritable Bowel Syndrome, represents the first use of psilocybin in conjunction with psychotherapy as a therapeutic intervention in patients with IBS.
Product Name : Undisclosed
Product Type : Controlled Substance
Upfront Cash : Inapplicable
May 24, 2023
Lead Product(s) : Psilocybine
Therapeutic Area : Gastroenterology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Crofelemer
Therapeutic Area : Gastroenterology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Mytesi (crofelemer) powder for oral solution inhibits both cAMP-stimulated CFTR chloride ion channel and the CaCC at the luminal membrane of enterocytes, which being investigated for the treatment of short bowel syndrome.
Product Name : Mytesi
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 08, 2023
Lead Product(s) : Crofelemer
Therapeutic Area : Gastroenterology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : EXE-346
Therapeutic Area : Gastroenterology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : EXE-346 is a live biotherapeutic product (LBP) a blend of probiotic bacteria formulated in extremely high potency. The product is currently under development to manage excessive stool frequency in patients who have undergone an ileal pouch-anal anastomos...
Product Name : Undisclosed
Product Type : Probiotic
Upfront Cash : Inapplicable
January 26, 2023
Lead Product(s) : EXE-346
Therapeutic Area : Gastroenterology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable