[{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"Omega Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Oligonucleotide","year":"2021","type":"Financing","leadProduct":"Inapplicable","moa":"||Myc expression","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Flagship Pioneering","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Flagship Pioneering \/ Flagship Pioneering","highestDevelopmentStatusID":"7","companyTruncated":"Flagship Pioneering \/ Flagship Pioneering"},{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"Montai Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2024","type":"Collaboration","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Oncology","graph2":"Discovery Platform","graph3":"Flagship Pioneering","amount2":0,"highestDevelopmentShortName":"Discovery Platform","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Flagship Pioneering \/ Flagship Pioneering","highestDevelopmentStatusID":"3","companyTruncated":"Flagship Pioneering \/ Flagship Pioneering"},{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"Evelo Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Microorganism","year":"2022","type":"Public Offering","leadProduct":"EDP1815","moa":"||IL-6 receptor","graph1":"Dermatology","graph2":"Phase II","graph3":"Flagship Pioneering","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Flagship Pioneering \/ Flagship Pioneering","highestDevelopmentStatusID":"8","companyTruncated":"Flagship Pioneering \/ Flagship Pioneering"},{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"Evelo Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Probiotic","year":"2023","type":"Private Placement","leadProduct":"EDP2939","moa":"||Undisclosed","graph1":"Dermatology","graph2":"Phase II","graph3":"Flagship Pioneering","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Flagship Pioneering \/ Flagship Pioneering","highestDevelopmentStatusID":"8","companyTruncated":"Flagship Pioneering \/ Flagship Pioneering"},{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"Senda Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2022","type":"Series C Financing","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Flagship Pioneering","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Flagship Pioneering \/ Flagship Pioneering","highestDevelopmentStatusID":"4","companyTruncated":"Flagship Pioneering \/ Flagship Pioneering"},{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"Abiologics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2024","type":"Financing","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Oncology","graph2":"Discovery Platform","graph3":"Flagship Pioneering","amount2":0,"highestDevelopmentShortName":"Discovery Platform","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Flagship Pioneering \/ Flagship Pioneering","highestDevelopmentStatusID":"3","companyTruncated":"Flagship Pioneering \/ Flagship Pioneering"},{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"ProFound Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Nutrition and Weight Loss","country":"U.S.A","productType":"Undisclosed","year":"2024","type":"Agreement","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Nutrition and Weight Loss","graph2":"Discovery Platform","graph3":"Flagship Pioneering","amount2":0,"highestDevelopmentShortName":"Discovery Platform","therapeuticAreaShortName":"Nutrition & Weight Loss","amount2New":0,"dosageForm":"Oral","sponsorNew":"Flagship Pioneering \/ Flagship Pioneering","highestDevelopmentStatusID":"3","companyTruncated":"Flagship Pioneering \/ Flagship Pioneering"},{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"Ampersand Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Nutrition and Weight Loss","country":"U.S.A","productType":"Undisclosed","year":"2024","type":"Collaboration","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Nutrition and Weight Loss","graph2":"Discovery Platform","graph3":"Flagship Pioneering","amount2":0,"highestDevelopmentShortName":"Discovery Platform","therapeuticAreaShortName":"Nutrition & Weight Loss","amount2New":0,"dosageForm":"Oral","sponsorNew":"Flagship Pioneering \/ Flagship Pioneering","highestDevelopmentStatusID":"3","companyTruncated":"Flagship Pioneering \/ Flagship Pioneering"},{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"Metaphore Biotechnologies","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Financing","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Immunology","graph2":"Discovery","graph3":"Flagship Pioneering","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Flagship Pioneering \/ Flagship Pioneering","highestDevelopmentStatusID":"2","companyTruncated":"Flagship Pioneering \/ Flagship Pioneering"},{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"Novo Nordisk","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"U.S.A","productType":"Undisclosed","year":"2022","type":"Collaboration","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Cardiology\/Vascular Diseases","graph2":"Discovery","graph3":"Flagship Pioneering","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Oral Inhalation","sponsorNew":"Flagship Pioneering \/ Novo Nordisk","highestDevelopmentStatusID":"2","companyTruncated":"Flagship Pioneering \/ Novo Nordisk"},{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"Empress Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Financing","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Immunology","graph2":"Discovery","graph3":"Flagship Pioneering","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Flagship Pioneering \/ Flagship Pioneering","highestDevelopmentStatusID":"2","companyTruncated":"Flagship Pioneering \/ Flagship Pioneering"},{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"Cellarity","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2022","type":"Series C Financing","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Oncology","graph2":"Discovery","graph3":"Flagship Pioneering","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Flagship Pioneering \/ Flagship Pioneering","highestDevelopmentStatusID":"2","companyTruncated":"Flagship Pioneering \/ Flagship Pioneering"},{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"GSK","pharmaFlowCategory":"D","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"U.S.A","productType":"Undisclosed","year":"2024","type":"Collaboration","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Discovery","graph3":"Flagship Pioneering","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Oral","sponsorNew":"Flagship Pioneering \/ GSK","highestDevelopmentStatusID":"2","companyTruncated":"Flagship Pioneering \/ GSK"},{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"Flagship Pioneering","pharmaFlowCategory":"D","therapeuticArea":"Technology","country":"","productType":"Undisclosed","year":"2023","type":"Agreement","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Technology","graph2":"Discovery","graph3":"Flagship Pioneering","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Technology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Flagship Pioneering \/ Flagship Pioneering","highestDevelopmentStatusID":"2","companyTruncated":"Flagship Pioneering \/ Flagship Pioneering"},{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"Syros Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Vitamins\/Minerals\/Inorganic Salts","year":"2022","type":"Private Placement","leadProduct":"Tamibarotene","moa":"||RAR-alpha","graph1":"Oncology","graph2":"Phase III","graph3":"Flagship Pioneering","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Injection","sponsorNew":"Flagship Pioneering \/ Flagship Pioneering","highestDevelopmentStatusID":"10","companyTruncated":"Flagship Pioneering \/ Flagship Pioneering"},{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"Flagship Pioneering","pharmaFlowCategory":"D","therapeuticArea":"Nutrition and Weight Loss","country":"","productType":"Undisclosed","year":"2025","type":"Series B Financing","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Nutrition and Weight Loss","graph2":"Discovery Platform","graph3":"Flagship Pioneering","amount2":0,"highestDevelopmentShortName":"Discovery Platform","therapeuticAreaShortName":"Nutrition & Weight Loss","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Flagship Pioneering \/ Flagship Pioneering","highestDevelopmentStatusID":"3","companyTruncated":"Flagship Pioneering \/ Flagship Pioneering"},{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"Alltrna","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Series B Financing","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Genetic Disease","graph2":"Discovery Platform","graph3":"Flagship Pioneering","amount2":0,"highestDevelopmentShortName":"Discovery Platform","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Flagship Pioneering \/ Flagship Pioneering","highestDevelopmentStatusID":"3","companyTruncated":"Flagship Pioneering \/ Flagship Pioneering"},{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"Pfizer Inc","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Undisclosed","year":"2025","type":"Collaboration","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Immunology","graph2":"Discovery Platform","graph3":"Flagship Pioneering","amount2":0,"highestDevelopmentShortName":"Discovery Platform","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Flagship Pioneering \/ Pfizer Inc","highestDevelopmentStatusID":"3","companyTruncated":"Flagship Pioneering \/ Pfizer Inc"},{"orgOrder":0,"company":"Flagship Pioneering","sponsor":"Cystic Fibrosis Foundation","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Undisclosed","year":"2021","type":"Partnership","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Genetic Disease","graph2":"Discovery","graph3":"Flagship Pioneering","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Nasal","sponsorNew":"Flagship Pioneering \/ Cystic Fibrosis Foundation","highestDevelopmentStatusID":"2","companyTruncated":"Flagship Pioneering \/ Cystic Fibrosis Foundation"}]

Find Clinical Drug Pipeline Developments & Deals by Flagship Pioneering

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : The collaboration aims to discover compounds which may lead to the development of next-generation therapeutics for autoimmune diseases.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          April 01, 2025

                          Lead Product(s) : Undisclosed,Inapplicable

                          Therapeutic Area : Immunology

                          Highest Development Status : Discovery Platform

                          Sponsor : Pfizer Inc

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          02

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : The financing will be used for Ampersand's AND™ Platform to identify programmed biologics for the treatment of obesity-related targets.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          March 19, 2025

                          Lead Product(s) : Undisclosed,Inapplicable

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Discovery Platform

                          Recipient : Ampersand Biomedicines

                          Deal Size : $65.0 million

                          Deal Type : Series B Financing

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                          03

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : ProFound will deploy its proprietary ProFoundry Platform in collaboration with Pioneering Medicines' expertise to discover novel proteins and evaluate their therapeutic relevance for obesity.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          December 06, 2024

                          Lead Product(s) : Undisclosed,Inapplicable

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Discovery Platform

                          Recipient : ProFound Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          04

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Under the collaboration, Montai's CONECTA™ AI platform will be used to identify small molecules directed to a potential Non-Small Cell Lung Cancer-related target.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          November 20, 2024

                          Lead Product(s) : Undisclosed,Inapplicable

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery Platform

                          Recipient : Montai Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          05

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Under the collaboration, Ampersand's AND™ Platform will be used to identify programmed biologics for the treatment of obesity-related targets.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          November 20, 2024

                          Lead Product(s) : Undisclosed,Inapplicable

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Discovery Platform

                          Recipient : Ampersand Biosciences

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          06

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : The Flagship collaborates with GSK to discover and develop a portfolio of future transformational medicines and vaccines for the treatment of respiratory and immunology diseases.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : $150.0 million

                          July 29, 2024

                          Lead Product(s) : Undisclosed,Inapplicable

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : Discovery

                          Sponsor : GSK

                          Deal Size : $7,200.0 million

                          Deal Type : Collaboration

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                          07

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : The proceeds will advance company's platform and develop a diverse pipeline of medicines, Synteins, with an initial focus on oncology and immunology indications.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          July 23, 2024

                          Lead Product(s) : Undisclosed,Inapplicable

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery Platform

                          Recipient : Abiologics

                          Deal Size : $50.0 million

                          Deal Type : Financing

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                          08

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : The company intends to use the net proceeds to fund the completion of the Company’s ongoing Phase 2a trial of EDP2939, an investigational orally delivered and gut-restricted bacterial extracellular vesicle being developed for the treatment of moderate ...

                          Product Name : Undisclosed

                          Product Type : Probiotic

                          Upfront Cash : Undisclosed

                          December 07, 2023

                          Lead Product(s) : EDP2939,Inapplicable

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Recipient : Evelo Biosciences

                          Deal Size : $25.5 million

                          Deal Type : Private Placement

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                          09

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : The financing will be used to advance the company's platform and first drug candidates towards the clinic for a first indication in Stop Codon Disease.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          September 08, 2023

                          Lead Product(s) : Undisclosed,Inapplicable

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Discovery Platform

                          Recipient : Alltrna

                          Deal Size : $109.0 million

                          Deal Type : Series B Financing

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                          10

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : The net proceeds will be used to support the development of Empress's proprietary Chemilogics™ product platform which creates potential small molecule medicines and the company's initial pipeline of drug candidates.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          June 21, 2023

                          Lead Product(s) : Undisclosed,Inapplicable

                          Therapeutic Area : Immunology

                          Highest Development Status : Discovery

                          Recipient : Empress Therapeutics

                          Deal Size : $50.0 million

                          Deal Type : Financing

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