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III","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Amolyt Pharma \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Amolyt Pharma \/ Inapplicable"}]

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                          01

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : AstraZeneca leverages AZP-3601 (neboparatide), a peptide agonist of the PTH1 receptor, currently in Phase III for treating chronic hypoparathyroidism and related endocrine diseases.

                          Product Name : AZP-3601

                          Product Type : Peptide

                          Upfront Cash : $800.0 million

                          March 14, 2024

                          Lead Product(s) : Eneboparatide

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase III

                          Sponsor : AstraZeneca

                          Deal Size : $1,050.0 million

                          Deal Type : Acquisition

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                          02

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : AZP-3601 (neboparatide) is a peptide agonist of the PTH1 receptor. Currently, being evaluated in the Phase III for Chronic Hypoparathyroidism, Endocrine System Diseases, and Parathyroid Diseases.

                          Product Name : AZP-3601

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          February 05, 2024

                          Lead Product(s) : Eneboparatide

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : AZP-3601 (eneboparatide) targets PTH receptor to safely produce sustained blood levels of calcium and thereby manage the symptoms of hypoparathyroidism, and to limit urine calcium excretion by restoring calcium reabsorption by the kidney, preventing chro...

                          Product Name : AZP-3601

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          February 05, 2023

                          Lead Product(s) : Eneboparatide

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : Phase 3 TIMES 2 and TIMES 3 trial results demonstrate that Imeglimin met its primary endpoints and objectives and was observed to exhibit a favorable safety and tolerability profile.

                          Product Name : Twymeeg

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          September 24, 2020

                          Lead Product(s) : Imeglimin Hydrochloride

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : Sumitomo Dainippon Pharma has submitted a Japanese New Drug Application (J-NDA) to the Pharmaceuticals and Medical Devices Agency (PMDA) to request approval for the manufacturing and marketing of Imeglimin for the treatment of type 2 diabetes.

                          Product Name : Twymeeg

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          July 30, 2020

                          Lead Product(s) : Imeglimin Hydrochloride

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase III

                          Sponsor : Sumitomo Pharma

                          Deal Size : $21.3 million

                          Deal Type : Agreement

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                          06

                          EPS
                          Not Confirmed
                          EPS
                          Not Confirmed

                          Details : Two drug-drug interaction studies assessed the effect of repeated co-administration of commonly prescribed medications, metformin or sitagliptin (Januvia®; Merck & Co.), with Imeglimin.

                          Product Name : Twymeeg

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          April 20, 2020

                          Lead Product(s) : Imeglimin Hydrochloride

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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