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Find Clinical Drug Pipeline Developments & Deals by Enanta Pharmaceuticals
EDP-323 is an oral, L-protein inhibitor in development for the treatment of respiratory syncytial virus. It has shown sub-nanomolar potency against several RSV-A and RSV-B strains in vitro.
EDP-235 is an oral, 3CL protease inhibitor, which is being investigated in non-hospitalized, symptomatic adults with mild or moderate COVID-19 who were not at high risk for severe disease.
EDP-235 is a 3CL protease inhibitor, having the ability to suppress viral replication and transmission. It is in development as an once-daily, oral formulation, treatment for COVID-19.
Through the divestment, Enanta will sale a Portion of Global Royalties on MAVYRET® (U.S.)/MAVIRET® (ex-U.S.) (glecaprevir/pibrentasvir) to OMERS Life Sciences. The net sale proceeds will be used to fund the continuing clinical development of virology pipeline.
EDP-323 is an oral, L-protein inhibitor in development for the treatment of respiratory syncytial virus. It has shown sub-nanomolar potency against several RSV-A and RSV-B strains in vitro.
EDP-235 is a 3CL protease inhibitor, having the ability to suppress viral replication and transmission. It is in development as an oral formulation, once-daily, treatment for COVID-19.
Preclinical data show that EDP-235 potently blocks the replication of SARS-CoV-2 in multiple cellular models. Preclinical studies also show that EDP-235 has favorable distribution into lung cells as well as other key target tissues.
EDP-235 achieved excellent penetration into monocytes and macrophages, including lung AM. EDP-235 has the potential to eliminate viral replication of SARS-CoV-2 in these critical immune cells, thus mitigating macrophage-mediated cytokine storm in high-risk COVID-19 patients.
EDP-323 is a potent inhibitor of respiratory syncytial virus (RSV) replication and has the potential to be a best-in-class, broad spectrum, once daily, oral antiviral treatment for respiratory syncytial virus (RSV).
EDP-938 is a nanomolar inhibitor of both RSV-A and RSV-B activity, in treatment of adults with acute respiratory syncytial virus (RSV) infection who are at high risk of complications.