Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Emapalumab
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
FDA Grants Priority Review to Sobi's Gamifant sBLA
Details : Gamifant (emapalumab) is an anti-IFNγ monoclonal antibody that binds free and receptor-bound IFNγ, neutralizing its biological activity. Emapalumab is currently in Phase lll development for MAS.
Product Name : Gamifant
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
February 27, 2025
Lead Product(s) : Emapalumab
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Emapalumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Swedish Orphan Biovitrum AB
Deal Size : Inapplicable
Deal Type : Inapplicable
Emapalumab Prevention of CAR-T Cell Associated Toxicities
Details : Emapalumab is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Lymphoma, Large B-Cell, Diffuse.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
August 12, 2024
Lead Product(s) : Emapalumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Swedish Orphan Biovitrum AB
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Emapalumab
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Sobi's Emapalumab-lzsg Gets FDA Fast Track For Macrophage Activation Syndrome
Details : Gamifant (emapalumab) is an anti-IFNγ monoclonal antibody that binds free and receptor-bound IFNγ, neutralizing its biological activity. Emapalumab is currently in Phase lll development for MAS.
Product Name : Gamifant
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
May 24, 2024
Lead Product(s) : Emapalumab
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Emapalumab
Therapeutic Area : Hematology
Study Phase : Phase II
Sponsor : Swedish Orphan Biovitrum AB
Deal Size : Inapplicable
Deal Type : Inapplicable
A Pilot Study of Emapalumab for the Treatment of CAR T-Cell Therapy-Associated Prolonged Cytopenia
Details : Emapalumab is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Cytopenia.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
February 29, 2024
Lead Product(s) : Emapalumab
Therapeutic Area : Hematology
Highest Development Status : Phase II
Sponsor : Swedish Orphan Biovitrum AB
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Emapalumab
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Gamifant (emapalumab-lzsg) is a fully human, anti-IFNγ mAb that binds free and receptor-bound IFNγ, neutralizing its biological activity. In the US, it is indicated for pediatric and adult primary hemophagocytic lymphohistiocytosis (HLH) patients.
Product Name : Gamifant
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
April 04, 2023
Lead Product(s) : Emapalumab
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Emapalumab
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Swedish Orphan Biovitrum AB
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Emapalumab is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Immune System Diseases.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
March 28, 2023
Lead Product(s) : Emapalumab
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Swedish Orphan Biovitrum AB
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Emapalumab
Therapeutic Area : Genetic Disease
Study Phase : Phase IV
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Gamifant (Emapalumab) is a Antibody drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Lymphohistiocytosis, Hemophagocytic.
Product Name : Gamifant
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
February 24, 2023
Lead Product(s) : Emapalumab
Therapeutic Area : Genetic Disease
Highest Development Status : Phase IV
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Emapalumab
Therapeutic Area : Genetic Disease
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Sobi to Present Data from REAL-HLH Study at the ACR Convergence 2022 Meeting
Details : Gamifant (emapalumab-lzsg) is an IFNγ blocking monoclonal antibody indicated for the treatment of adult and pediatric (newborn and older) patients with primary HLH with refractory, recurrent or progressive disease or intolerance with conventional HLH th...
Product Name : Gamifant
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
October 27, 2022
Lead Product(s) : Emapalumab
Therapeutic Area : Genetic Disease
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Emapalumab
Therapeutic Area : Genetic Disease
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Gamifant (emapalumab) is a mAb that binds to and neutralizes interferon-gamma (IFNy), is the first and only medicine approved in the US and UAE for primary HLH, also has received approval by NMPA of China.
Product Name : Gamifant
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
February 25, 2022
Lead Product(s) : Emapalumab
Therapeutic Area : Genetic Disease
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Emapalumab
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Emapalumab is a Antibody drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Macrophage Activation Syndrome.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
August 12, 2021
Lead Product(s) : Emapalumab
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable