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                          01

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : RF1V-1018 Vaccine is a Vaccine candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Plague.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          October 06, 2025

                          Lead Product(s) : rF1V-1018 Vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : US Department of Defense

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Z-1018 is a Vaccine drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Herpes Zoster.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          August 26, 2024

                          Lead Product(s) : Z-1018

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Z-1018 is an investigational shingles vaccine candidate that uses Dynavax's CpG 1018 adjuvant to enhance the immune response. It ie being evaluated for prevention of shingles (herpes zoster).

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          June 27, 2024

                          Lead Product(s) : Z-1018

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Heplisav-B (adjuvanted recombinant hepatitis B vaccine) is a single-dose, prefilled syringe given intramuscularly. FDA in its CRL declines the expanded use of vaccine due to insufficient data.

                          Product Name : Heplisav-B

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          May 14, 2024

                          Lead Product(s) : Hepatitis B Vaccine Recombinant, Adjuvanted

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : sBLA has been submitted to include a four-dose HEPLISAV-B® vaccine [Hepatitis B Vaccine (Recombinant), Adjuvanted] regimen for adults with hepatitis-B on hemodialysis.

                          Product Name : Heplisav-B

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          May 14, 2024

                          Lead Product(s) : Hepatitis B Vaccine Recombinant, Adjuvanted

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          06

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Heplisav-B (adjuvanted recombinant hepatitis B vaccine) combines hepatitis B surface antigen with a proprietary Toll-like Receptor 9 agonist to enhance the immune response.

                          Product Name : Heplisav-B

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          February 28, 2023

                          Lead Product(s) : Hepatitis B Vaccine Recombinant, Adjuvanted

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : HEPLISAV-B [Hepatitis B Vaccine (Recombinant), Adjuvanted] Solution for Intramuscular Injection,B is indicated for prevention of infection caused by all known subtypes of hepatitis B virus.

                          Product Name : Heplisav-B

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          October 22, 2022

                          Lead Product(s) : Hepatitis B Vaccine Recombinant, Adjuvanted

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Recipient : National Institute of Allergy and Infectious Diseases

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : RF1V vaccine is a Vaccine drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Plague.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          August 18, 2022

                          Lead Product(s) : rF1V vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : US Department of Defense

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Z-1018 is a Vaccine drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Herpes Zoster.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          February 18, 2022

                          Lead Product(s) : Z-1018

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Under the agreement, Dynavax will conduct a phase 2 clinical trial combining its CpG 1018 adjuvant with the DOD's rF1V vaccine. CpG 1018 is the adjuvant used in HEPLISAV-B.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          October 05, 2021

                          Lead Product(s) : Plague Vaccine Recombinant,CPG ODN 1018

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : IND Enabling

                          Sponsor : US Department of Defense

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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