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Pediatric Neuro-Oncology Consortium"}]

Find Clinical Drug Pipeline Developments & Deals for Dordaviprone

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                          01

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : Through the acquisition, Jazz will strengthen it's oncology pipeline, which includes ONC201 (dordaviprone). It is being evaluated in the late-stage for the treatment of H3 K27M-mutant diffuse glioma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : $935.0 million

                          April 21, 2025

                          Lead Product(s) : Dordaviprone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Jazz Pharmaceuticals

                          Deal Size : $935.0 million

                          Deal Type : Acquisition

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                          02

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : Through the acquisition, Jazz will strengthen it's oncology pipeline, which includes ONC201 (dordaviprone). It is being in the evaluated late-stage for the treatment of H3 K27M-mutant diffuse glioma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : $935.0 million

                          March 05, 2025

                          Lead Product(s) : Dordaviprone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Jazz Pharmaceuticals

                          Deal Size : $935.0 million

                          Deal Type : Acquisition

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                          03

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : ONC201 (dordaviprone) is a novel first-in-class small molecule imipridone that selectively targets the mitochondrial protease ClpP and dopamine receptor D2 for recurrent H3 K27M-Mutant diffuse glioma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          February 18, 2025

                          Lead Product(s) : Dordaviprone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : ONC201 (dordaviprone) is a novel first-in-class small molecule imipridone that selectively targets the mitochondrial protease ClpP and dopamine receptor D2 for recurrent H3 K27M-Mutant diffuse glioma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          December 30, 2024

                          Lead Product(s) : Dordaviprone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : ONC201 (dordaviprone) targets the targets the mitochondrial protease ClpP and dopamine receptor D2. It is being evaluated for the treatment of recurrent H3 K27M-mutant diffuse glioma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          December 09, 2024

                          Lead Product(s) : Dordaviprone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          University of Nebraska

                          Country arrow
                          Luxepack
                          Not Confirmed

                          University of Nebraska

                          Country arrow
                          Luxepack
                          Not Confirmed

                          Details : ONC201 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Meningioma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          August 28, 2023

                          Lead Product(s) : Dordaviprone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Chimerix

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : ONC201 is a new drug candidate that kills cancer cells but not normal cells in laboratory studies and has been previously evaluated in a phase I clinical trial in advanced cancer patients.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          December 08, 2022

                          Lead Product(s) : Dordaviprone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : Dordaviprone is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Glioma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          October 14, 2022

                          Lead Product(s) : Dordaviprone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Gustave Roussy

                          Country arrow
                          PackExpo
                          Not Confirmed

                          Gustave Roussy

                          Country arrow
                          PackExpo
                          Not Confirmed

                          Lead Product(s) : Dordaviprone

                          Therapeutic Area : Oncology

                          Study Phase : Phase III

                          Sponsor : Chimerix | Innovative Therapies for Children with Cancer Consortium | Ministry of Health, France

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : ONC201 is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Diffuse Intrinsic Pontine Glioma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          July 27, 2022

                          Lead Product(s) : Dordaviprone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Chimerix | Innovative Therapies for Children with Cancer Consortium | Ministry of Health, France

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : ONC201 is a Other Small Molecule drug candidate, which is currently being evaluated in clinical studies for the treatment of Glioma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          May 26, 2022

                          Lead Product(s) : Dordaviprone

                          Therapeutic Area : Oncology

                          Highest Development Status : Undisclosed

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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