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    Find Dermatology Drugs in Phase III Clinical Development in JAPAN

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              Otsuka Pharmaceutical

              • Development Update

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              JAPAN Japan

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              CPhI Discover 2021

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              Otsuka Has Filed an Application in Japan for Approval of Difamilast (OPA-15406) as an Atopic Dermatitis Drug

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              Lead Product(s): Difamilast

              Therapeutic Area: Dermatology Product Name: OPA-15406

              Highest Development Status: Phase III Product Type: Small molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable September 28, 2020

              Details:

              Difamilast is a topical atopic dermatitis drug candidate discovered by Otsuka that has phosphodiesterase 4 (PDE4) inhibitory activity.

              Chugai Pharmaceutical

              • Development Update

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              JAPAN Japan

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              CPhI Discover 2021

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              Results of Maruho’s Phase III Study with Chugai’s Nemolizumab for Atopic Dermatitis Published in The New England Journal of Medicine Onl...

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              Lead Product(s): Nemolizumab

              Therapeutic Area: Dermatology Product Name: Undisclosed

              Highest Development Status: Phase III Product Type: Large molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable July 09, 2020

              Details:

              Nemolizumab is an anti-interleukin-31 (IL-31) receptor A humanized monoclonal antibody created by Chugai.

              Otsuka Pharmaceutical

              • Development Update

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              JAPAN Japan

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              CPhI Discover 2021

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              Medimetriks Announces that Otsuka Achieved Positive Top-Line Phase 3 Results for MM36

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              Lead Product(s): Difamilast

              Therapeutic Area: Dermatology Product Name: Undisclosed

              Highest Development Status: Phase III Product Type: Small molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable March 27, 2020

              Details:

              Difamilast (OPA-15406) me primary end points in patients with atopic dermatitis, in both the adult and pediatric trials.

              Torii Pharmaceutical

              • Deals

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              JAPAN Japan

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              CPhI Discover 2021

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              JT to market CORECTIM in Japan to treat atopic dermatitis

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              Lead Product(s): Delgocitinib

              Therapeutic Area: Dermatology Product Name: Undisclosed

              Highest Development Status: Phase III Product Type: Small molecule

              Partner/Sponsor/Collaborator: Japan Tobacco

              Deal Size: Undisclosed Upfront Cash: Undisclosed

              Deal Type: Licensing Agreement January 15, 2020

              Details:

              Under the terms of the agreement on October 2016nbetween JT and Torii, the drugs will be sold exclusively by Torii in Japan, following itsninclusion in the National Health Insurance (NHI) price list.

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