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Details:
Padagis's Paragraph IV Abbreviated New Drug Application filing for crisaborole ointment 2%, asserting patents listed in Orange Book for Eucrisa®. Padagis's first-to-file ANDA for generic version of Eucrisa® (crisaborole ointment 2%) for treatment of atopic dermatitis.
Lead Product(s):
Crisaborole
Therapeutic Area: Dermatology
Product Name: Undisclosed
Highest Development Status: Phase III
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
September 28, 2021
Details:
CF101 (piclidenoson) is novel, first-in-class, A3 adenosine receptor agonist (A3AR) small molecule, orally bioavailable drug with an excellent safety profile demonstrating evidence of efficacy in Phase II clinical studies.
Lead Product(s):
Piclidenoson
Therapeutic Area: Dermatology
Product Name: CF101
Highest Development Status: Phase III
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
September 12, 2022
Details:
CF101 (piclidenoson) is a novel, first-in-class, A3 adenosine receptor agonist (A3AR) small molecule, orally bioavailable drug with an excellent safety profile demonstrating evidence of efficacy in Phase II clinical studies.
Lead Product(s):
Piclidenoson
Therapeutic Area: Dermatology
Product Name: CF101
Highest Development Status: Phase III
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
August 22, 2022
Details:
CF101 (piclidenoson) is a novel, first-in-class, A3 adenosine receptor agonist (A3AR) small molecule, orally bioavailable drug with an excellent safety profile demonstrating evidence of efficacy in Phase II clinical studies.
Lead Product(s):
Piclidenoson
Therapeutic Area: Dermatology
Product Name: CF101
Highest Development Status: Phase III
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
July 11, 2022
Details:
Data suggest Piclidenoson (CF101) and Namodenoson could potentially be the first A3AR agonists to achieve FDA approval and provide clinicians with new oral and safe drugs in the arsenal for fighting psoriasis, liver cancer, and NASH.
Lead Product(s):
Piclidenoson
Therapeutic Area: Dermatology
Product Name: CF101
Highest Development Status: Phase III
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
June 09, 2022
Details:
CF101 (piclidenoson), is an oral drug that is currently in a Phase III clinical study for the treatment of psoriasis. All human clinical studies have demonstrated this drug to have an excellent safety profile.
Lead Product(s):
Piclidenoson
Therapeutic Area: Dermatology
Product Name: CF101
Highest Development Status: Phase III
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
March 28, 2022
Details:
CF101 (piclidenoson), an A3 adenosine receptor agonist involving inhibition of 2 cytokines, interleukin-17 and interleukin-23, are both pivotal for the formation of skin lesions. Piclidenoson has also recently been shown to induce death of pathological skin cells.
Lead Product(s):
Piclidenoson
Therapeutic Area: Dermatology
Product Name: CF101
Highest Development Status: Phase III
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
March 08, 2022
Details:
Piclidenoson is a novel, first-in-class, A3 adenosine receptor agonist (A3AR) small molecule, orally bioavailable drug with a favorable therapeutic index demonstrated in Phase II clinical studies.
Lead Product(s):
Piclidenoson
Therapeutic Area: Dermatology
Product Name: CF101
Highest Development Status: Phase III
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
December 07, 2021
Details:
Piclidenoson is a novel, first-in-class, A3 adenosine receptor agonist (A3AR) small molecule, orally bioavailable drug with a favorable therapeutic index demonstrated in Phase II clinical studies.
Lead Product(s):
Piclidenoson
Therapeutic Area: Dermatology
Product Name: CF101
Highest Development Status: Phase III
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
September 02, 2021
Details:
75% of patients have been enrolled in Can-Fite’s Phase III Comfort™ study designed to establish Piclidenoson’s superiority compared to placebo and non-inferiority compared to Apremilast (Otezla®) in patients with moderate to severe plaque psoriasis.
Lead Product(s):
Piclidenoson
Therapeutic Area: Dermatology
Product Name: CF101
Highest Development Status: Phase III
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
April 29, 2021
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