Israel

Can-Fite BioPharma

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ISRAEL Israel

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Drug Discovery Chemistry

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Can-Fite Implements Interim Analysis for its Phase III Psoriasis Trial with Data Expected Q4 2020

Lead Product(s): Piclidenoson

Therapeutic Area: Dermatology

Highest Development Status: Phase III Product Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 30, 2020

Details:

Interim analysis of the Phase III Comfort trial designed to evaluate the Company’s drug candidate, Piclidenoson, in the treatment of moderate-to-severe plaque psoriasis.

Foamix Pharmaceuticals

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ISRAEL Israel

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Drug Discovery Chemistry

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Menlo Therapeutics and Foamix Pharmaceuticals Complete Merger

Lead Product(s): Serlopitant

Therapeutic Area: Dermatology

Highest Development Status: Phase III Product Type: Small molecule

Partner/Sponsor/Collaborator: Menlo Therapeutics

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Merger March 09, 2020

Details:

The combined company already has an approved, commercial-stage product, AMZEEQ™, and several late-stage product candidates.

Can-Fite BioPharma

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ISRAEL Israel

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Drug Discovery Chemistry

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Can-Fite is Filing Drug Safety Update Report Showing Positive Safety Results

Lead Product(s): Piclidenoson

Therapeutic Area: Dermatology

Highest Development Status: Phase III Product Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 03, 2020

Details:

This year, Can-Fite's reports expand the growing data body demonstrating that both Piclidenoson and Namodenoson have beneficial safety profiles and risk-benefit ratios in over 1,500 patients.

Sol-Gel Technologies

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ISRAEL Israel

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Drug Discovery Chemistry

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Sol-Gel Announces Positive Topline Results from Open-Label, Long-Term Safety Study of Epsolay® for Treatment up to 52 Weeks

Lead Product(s): Benzoyl Peroxide

Therapeutic Area: Dermatology

Highest Development Status: Phase III Product Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 13, 2020

Details:

Successful topline results, strengthens Epsolay’s long-term safety and tolerability profile in the treatment of papulopustular rosacea. Results pave the way for NDA submission in 2020.

Foamix Pharmaceuticals

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ISRAEL Israel

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Drug Discovery Chemistry

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Foamix Announces Publication of Phase 3 Studies Evaluating FMX103

Lead Product(s): Minocycline

Therapeutic Area: Dermatology

Highest Development Status: Phase III Product Type: Small molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 06, 2020

Details:

Both studies demonstrated statistically significant superiority of FMX103 compared with vehicle in both primary endpoints of absolute inflammatory lesion reduction.

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Companies

Can-Fite BioPharma

Can-Fite Implements Interim Analysis for its Phase III Psoriasis Trial with Data Expected Q4 2020

Foamix Pharmaceuticals

Menlo Therapeutics and Foamix Pharmaceuticals Complete Merger

Can-Fite BioPharma

Can-Fite is Filing Drug Safety Update Report Showing Positive Safety Results

Sol-Gel Technologies

Sol-Gel Announces Positive Topline Results from Open-Label, Long-Term Safety Study of Epsolay® for Treatment up to 52 Weeks

Foamix Pharmaceuticals

Foamix Announces Publication of Phase 3 Studies Evaluating FMX103