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    [{"orgOrder":0,"company":"Idorsia Pharmaceuticals","sponsor":"Jiangsu Simcere Pharmaceutical","pharmaFlowCategory":"D","therapeuticArea":"Sleep","country":"SWITZERLAND","productType":"Controlled Substance","year":"2022","type":"Licensing Agreement","leadProduct":"Daridorexant","moa":"OX1\/2 receptor","graph1":"Sleep","graph2":"Approved FDF","graph3":"Idorsia Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Sleep","amount2New":0,"dosageForm":"Oral Tablet, Film Coated","sponsorNew":"Idorsia Pharmaceuticals \/ Jiangsu Simcere Pharmaceutical","highestDevelopmentStatusID":"15","companyTruncated":"Idorsia Pharmaceuticals \/ Jiangsu Simcere Pharmaceutical"},{"orgOrder":0,"company":"Idorsia Pharmaceuticals","sponsor":"Mochida Pharmaceutical","pharmaFlowCategory":"DU","therapeuticArea":"Sleep","country":"SWITZERLAND","productType":"Controlled Substance","year":"2022","type":"Inapplicable","leadProduct":"Daridorexant","moa":"OX1\/2 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FDF","graph3":"Idorsia Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Sleep","amount2New":0,"dosageForm":"Oral Tablet, Film Coated","sponsorNew":"Idorsia Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Idorsia Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Idorsia Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Sleep","country":"SWITZERLAND","productType":"Controlled Substance","year":"2020","type":"Inapplicable","leadProduct":"Daridorexant","moa":"OX1\/2 receptor","graph1":"Sleep","graph2":"Approved FDF","graph3":"Idorsia Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Sleep","amount2New":0,"dosageForm":"Oral Tablet, Film Coated","sponsorNew":"Idorsia Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Idorsia Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Idorsia 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Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Sleep","country":"U.S.A","productType":"Controlled Substance","year":"2020","type":"Collaboration","leadProduct":"Daridorexant","moa":"OX1\/2 receptor","graph1":"Sleep","graph2":"Phase III","graph3":"Syneos Health","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Sleep","amount2New":0,"dosageForm":"Oral Tablet, Film Coated","sponsorNew":"Syneos Health \/ Idorsia Pharmaceuticals","highestDevelopmentStatusID":"10","companyTruncated":"Syneos Health \/ Idorsia Pharmaceuticals"}]

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    Daridorexant

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                            01

                            Idorsia Pharmaceuticals

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                            Lead Product(s) : Daridorexant

                            Therapeutic Area : Sleep

                            Study Phase : Approved FDF

                            Sponsor : Jiangsu Simcere Pharmaceutical

                            Deal Size : $50.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Simcere and Idorsia Enter Into a Licensing Agreement for Daridorexant in China

                            Details : Under the agreement, Simcere will be granted an exclusive right to develop and commercialize daridorexant (ACT-541468) in the Greater China region (Mainland China, Hong Kong, and Macau), one of the world's largest pharmaceutical markets.

                            Product Name : ACT-541468

                            Product Type : Controlled Substance

                            Upfront Cash : $30.0 million

                            November 16, 2022

                            Lead Product(s) : Daridorexant

                            Therapeutic Area : Sleep

                            Highest Development Status : Approved FDF

                            Sponsor : Jiangsu Simcere Pharmaceutical

                            Deal Size : $50.0 million

                            Deal Type : Licensing Agreement

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                            02

                            Idorsia Pharmaceuticals

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                            Lead Product(s) : Daridorexant

                            Therapeutic Area : Sleep

                            Study Phase : Approved FDF

                            Sponsor : Mochida Pharmaceutical

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Idorsia Japan Announces Positive Results With Daridorexant In A Phase 3 Study Of Japanese Patients With Insomn...

                            Details : The study met both primary and secondary efficacy endpoint measures ACT-541468 (Daridorexant) significantly improved sTST from baseline compared to placebo at 28 days (p<0.001 for 50 mg, p=0.042 for 25 mg).

                            Product Name : ACT-541468

                            Product Type : Controlled Substance

                            Upfront Cash : Inapplicable

                            March 10, 2022

                            Lead Product(s) : Daridorexant

                            Therapeutic Area : Sleep

                            Highest Development Status : Approved FDF

                            Sponsor : Mochida Pharmaceutical

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Idorsia Pharmaceuticals

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                            Lead Product(s) : Daridorexant

                            Therapeutic Area : Sleep

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Idorsia to Present New Phase 3 Data on Daridorexant in Insomnia at Sleep 2021

                            Details : The placebo-controlled studies investigated the effects of three doses of daridorexant (10 mg, 25 mg, and 50 mg) on sleep and daytime functioning parameters, objectively in a sleep lab by polysomnography and subjectively with a daily patient diary at hom...

                            Product Name : ACT-541468

                            Product Type : Controlled Substance

                            Upfront Cash : Inapplicable

                            September 06, 2021

                            Lead Product(s) : Daridorexant

                            Therapeutic Area : Sleep

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Idorsia Pharmaceuticals

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                            Lead Product(s) : Daridorexant

                            Therapeutic Area : Sleep

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : $588.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Idorsia Successfully Completes Capital Increase with Gross Proceeds of CHF 535.5 Million

                            Details : The increased liquidity will be used to prepare for the launch of daridorexant and further fund Idorsia’s diversified pipeline.

                            Product Name : ACT-541468

                            Product Type : Controlled Substance

                            Upfront Cash : Undisclosed

                            October 21, 2020

                            Lead Product(s) : Daridorexant

                            Therapeutic Area : Sleep

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : $588.0 million

                            Deal Type : Financing

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                            05

                            Syneos Health

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                            Lead Product(s) : Daridorexant

                            Therapeutic Area : Sleep

                            Study Phase : Phase III

                            Sponsor : Idorsia Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Idorsia Selects Syneos Health as Commercialization Partner to Launch Daridorexant in the United States

                            Details : The strategic collaboration brings Idorsia’s lead investigational compound, daridorexant, and expertise in the science of the orexin system, together with Syneos Health’s robust customer-facing sales expertise and proven track record in launching new...

                            Product Name : Undisclosed

                            Product Type : Controlled Substance

                            Upfront Cash : Undisclosed

                            August 31, 2020

                            Lead Product(s) : Daridorexant

                            Therapeutic Area : Sleep

                            Highest Development Status : Phase III

                            Sponsor : Idorsia Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            06

                            Idorsia Pharmaceuticals

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                            Lead Product(s) : Daridorexant

                            Therapeutic Area : Sleep

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Daridorexant Phase 3 Results In Insomnia to be Presented at Sleep 2020

                            Details : Results from the first pivotal Phase 3 study investigating 25 and 50 mg doses of its dual orexin receptor antagonist, daridorexant, in adult and elderly patients with insomnia, are to be presented at SLEEP 2020.

                            Product Name : ACT-541468

                            Product Type : Controlled Substance

                            Upfront Cash : Inapplicable

                            August 13, 2020

                            Lead Product(s) : Daridorexant

                            Therapeutic Area : Sleep

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Idorsia Pharmaceuticals

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                            Idorsia Pharmaceuticals

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                            Lead Product(s) : Daridorexant

                            Therapeutic Area : Sleep

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : $632.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Idorsia Announces Capital Increase to Prepare for the Launch of Daridorexant and Further Fund Its Diversified ...

                            Details : The proceeds from the offering will be used to support the regulatory filing and, if approved, commercial launch of daridorexant and to fund the further development of its diversified pipeline.

                            Product Name : ACT-541468

                            Product Type : Controlled Substance

                            Upfront Cash : Undisclosed

                            August 10, 2020

                            Lead Product(s) : Daridorexant

                            Therapeutic Area : Sleep

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : $632.0 million

                            Deal Type : Financing

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                            08

                            Idorsia Pharmaceuticals

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                            Lead Product(s) : Daridorexant

                            Therapeutic Area : Sleep

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Idorsia Japan Confirms Daridorexant Dose Response in Japanese Patients with Insomnia

                            Details : Treatment with daridorexant in 47 adult patients (ranging from 16 to 64 years) showed a significant dose-dependent decrease in WASO at Day 1 & 2 (average decrease of wake time after sleep onset from baseline on the 2 nights of treatment.

                            Product Name : ACT-541468

                            Product Type : Controlled Substance

                            Upfront Cash : Inapplicable

                            June 08, 2020

                            Lead Product(s) : Daridorexant

                            Therapeutic Area : Sleep

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Idorsia Pharmaceuticals

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                            Lead Product(s) : Daridorexant

                            Therapeutic Area : Sleep

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Second PhIII Study for Idorsia's Sleep Drug Returns Positive Results

                            Details : The study confirms the findings of the first pivotal study, demonstrating efficacy of treatment with daridorexant on objective and subjective sleep parameters and showed positive effects on daytime functioning, with patients reporting no morning sleepine...

                            Product Name : ACT-541468

                            Product Type : Controlled Substance

                            Upfront Cash : Inapplicable

                            June 07, 2020

                            Lead Product(s) : Daridorexant

                            Therapeutic Area : Sleep

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Idorsia Pharmaceuticals

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                            Lead Product(s) : Daridorexant

                            Therapeutic Area : Sleep

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Idorsia's Rival to Merck's Insomnia Drug Clears Phase 3 Test

                            Details : The study demonstrated efficacy of treatment with daridorexant on objective and subjective sleep parameters and daytime performance with no residual effect in the morning.

                            Product Name : ACT-541468

                            Product Type : Controlled Substance

                            Upfront Cash : Inapplicable

                            April 20, 2020

                            Lead Product(s) : Daridorexant

                            Therapeutic Area : Sleep

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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