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Boilson","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2022","type":"Inapplicable","leadProduct":"Daratumumab","moa":"Lymphocyte differentiation antigen CD38","graph1":"Undisclosed","graph2":"Phase II","graph3":"JANSSEN BIOTECH","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"JANSSEN BIOTECH \/ Barry A. Boilson","highestDevelopmentStatusID":"8","companyTruncated":"JANSSEN BIOTECH \/ Barry A. Boilson"}]

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                            Lead Product(s) : Daratumumab

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Phase I/ Phase II

                            Sponsor : Janssen-Cilag | INSERM U1111

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                            Anti-CD38 Monoclonal Antibodies in Toxic Epidermal Necrolysis

                            Details : Daratumumab is a Antibody drug candidate, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of Stevens-Johnson Syndrome.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            August 07, 2025

                            Lead Product(s) : Daratumumab

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Janssen-Cilag | INSERM U1111

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Memorial Sloan Kettering Cancer Center

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                            Memorial Sloan Kettering Cancer Center

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                            Not Confirmed
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                            Lead Product(s) : Daratumumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study of Dara-RVd and Teclistamab-RVd in People with Multiple Myeloma

                            Details : Daratumumab is a Antibody drug candidate, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of Multiple Myeloma.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            August 01, 2025

                            Lead Product(s) : Daratumumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Halozyme Therapeutics

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                            Halozyme Therapeutics

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                            Lead Product(s) : Daratumumab,Recombinant Human Hyaluronidase PH20

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            EC Approves DARZALEX Faspro For Smouldering Multiple Myeloma

                            Details : Darzalex Faspro (daratumumab) co-formulated with Enhanze, is approved as monotherapy for the treatment of adult patients with smouldering multiple myeloma at high-risk of developing multiple myeloma.

                            Product Name : Darzalex Faspro

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            July 23, 2025

                            Lead Product(s) : Daratumumab,Recombinant Human Hyaluronidase PH20

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            University of Maryland, Baltimore

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                            University of Maryland, Baltimore

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                            Lead Product(s) : Daratumumab

                            Therapeutic Area : Hematology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Johnson & Johnson

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Subcutaneous Daratumumab Administration in the Thigh Vs Abdomen in Plasma Cell Disorders

                            Details : Daratumumab is a Antibody drug candidate, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of Paraproteinemias.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            July 20, 2025

                            Lead Product(s) : Daratumumab

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Johnson & Johnson

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Celltrion

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                            Celltrion

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                            Lead Product(s) : Daratumumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            A Study to Compare Pharmacokinetics, Efficacy and Safety of Subcutaneous CT-P44 and Darzalex Faspro in Combina...

                            Details : Daratumumab is a Antibody drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Multiple Myeloma.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            May 01, 2025

                            Lead Product(s) : Daratumumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Johnson & Johnson Innovative Medicine

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                            Johnson & Johnson Innovative Medicine

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                            Lead Product(s) : Daratumumab,Bortezomib,Lenalidomide

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            EU Approves Subcutaneous DARZALEX Quad Combo for New Myeloma Patients

                            Details : Darzalex (daratumumab) a CD38 inhibitor, being evaluated in combination with bortezomib, lenalidomide, dexamethasone for the treatment of newly diagnosed multiple myeloma.

                            Product Name : Darzalex

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            April 07, 2025

                            Lead Product(s) : Daratumumab,Bortezomib,Lenalidomide

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Johnson & Johnson Innovative Medicine

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                            Johnson & Johnson Innovative Medicine

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                            Lead Product(s) : Daratumumab,Bortezomib,Lenalidomide

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            DARZALEX® Subcutaneous Regimen Gets CHMP Positive Opinion for Multiple Myeloma

                            Details : Darzalex (daratumumab) a CD38 inhibitor, being evaluated in combination with bortezomib, lenalidomide, dexamethasone for the treatment of newly diagnosed multiple myeloma.

                            Product Name : Darzalex

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            February 28, 2025

                            Lead Product(s) : Daratumumab,Bortezomib,Lenalidomide

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Shanghai Henlius Biotech

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                            Shanghai Henlius Biotech

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                            Not Confirmed
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                            Lead Product(s) : Daratumumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Dr. Reddy\'s Laboratories

                            Deal Size : $131.6 million

                            Deal Type : Licensing Agreement

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                            Dr. Reddy's, Henlius Collaborate on HLX15 Biosimilar for U.S. & EU

                            Details : Under the licensing agreement, Dr. Reddy’s gets exclusive rights to commercialize the subcutaneous as well as intravenous formulations of HLX15 (daratumumab) in the U.S. and Europe.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : $33.0 million

                            February 06, 2025

                            Lead Product(s) : Daratumumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Dr. Reddy\'s Laboratories

                            Deal Size : $131.6 million

                            Deal Type : Licensing Agreement

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                            09

                            Johnson & Johnson Innovative Medicine

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                            Johnson & Johnson Innovative Medicine

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                            Lead Product(s) : Teclistamab,Daratumumab,Dexamethasone

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            TECVAYLI® Shows Potential in Frontline Combo for Newly Diagnosed Myeloma

                            Details : Tecvayli (teclistamab) is a BCMA directed CD3 T-cell engager which is being evaluated for the treatment of patients with newly diagnosed multiple myeloma.

                            Product Name : Tecvayli

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            December 08, 2024

                            Lead Product(s) : Teclistamab,Daratumumab,Dexamethasone

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Johnson & Johnson

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                            Johnson & Johnson

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                            Lead Product(s) : Daratumumab,Hyaluronidase

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Johnson & Johnson Submits DARZALEX® Applications for Myeloma Approval

                            Details : Darzalex Faspro (daratumumab and hyaluronidase-fihj) in is being investgated as monotherapy for the treatment of adult patients with high-risk smouldering multiple myeloma.

                            Product Name : Darzalex

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            November 08, 2024

                            Lead Product(s) : Daratumumab,Hyaluronidase

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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