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American Regent","highestDevelopmentStatusID":"15","companyTruncated":"Daiichi Sankyo \/ American Regent"},{"orgOrder":0,"company":"Daiichi Sankyo","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Other Large Molecule","year":"2023","type":"Inapplicable","leadProduct":"Raludotatug Deruxtecan","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase II\/ Phase III","graph3":"Daiichi Sankyo","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Daiichi Sankyo \/ Inapplicable","highestDevelopmentStatusID":"9","companyTruncated":"Daiichi Sankyo \/ Inapplicable"},{"orgOrder":0,"company":"Daiichi Sankyo","sponsor":"Merck & Co","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Other Large Molecule","year":"2024","type":"Inapplicable","leadProduct":"Raludotatug 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Disease","graph2":"Undisclosed","graph3":"Daiichi Sankyo","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Daiichi Sankyo \/ Mitsubishi UFJ Capital","highestDevelopmentStatusID":"1","companyTruncated":"Daiichi Sankyo \/ Mitsubishi UFJ Capital"},{"orgOrder":0,"company":"Daiichi Sankyo","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Antibody-drug Conjugate","year":"2023","type":"Inapplicable","leadProduct":"Ifinatamab Deruxtecan","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Daiichi Sankyo","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Daiichi Sankyo \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Daiichi Sankyo \/ Inapplicable"},{"orgOrder":0,"company":"Daiichi Sankyo","sponsor":"Sarah Cannon Research Institute","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Antibody-drug Conjugate","year":"2021","type":"Inapplicable","leadProduct":"O-(3,5-Dichlorophenyl)hydroxylamine","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase II","graph3":"Daiichi Sankyo","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Daiichi Sankyo \/ Sarah Cannon Research Institute","highestDevelopmentStatusID":"8","companyTruncated":"Daiichi Sankyo \/ Sarah Cannon Research Institute"},{"orgOrder":0,"company":"Daiichi Sankyo","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Antibody-drug 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AstraZeneca","highestDevelopmentStatusID":"10","companyTruncated":"Daiichi Sankyo \/ AstraZeneca"},{"orgOrder":0,"company":"Daiichi Sankyo","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Antibody-drug Conjugate","year":"2020","type":"Inapplicable","leadProduct":"Deruxtecan","moa":"DNA topoisomerase I","graph1":"Oncology","graph2":"Phase II","graph3":"Daiichi Sankyo","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Daiichi Sankyo \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Daiichi Sankyo \/ Inapplicable"},{"orgOrder":0,"company":"Daiichi Sankyo","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"JAPAN","productType":"Antibody-drug Conjugate","year":"2020","type":"Inapplicable","leadProduct":"Deruxtecan","moa":"DNA topoisomerase 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Sankyo","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Oral Tablet, Film Coated","sponsorNew":"Daiichi Sankyo \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Daiichi Sankyo \/ Inapplicable"}]

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                            Lead Product(s) : Ifinatamab deruxtecan

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Merck & Co

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Daiichi’s Phase 3 IDeate-Esophageal01 Trial Starts for Ifinatamab Deruxtecan

                            Details : I-DXd (ifinatamab deruxtecan) is comprised of a humanized anti-B7-H3 IgG1 monoclonal antibody being investigated for unresectable advanced or metastatic esophageal squamous cell carcinoma.

                            Product Name : I-DXd

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            May 19, 2025

                            Lead Product(s) : Ifinatamab deruxtecan

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Merck & Co

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Daiichi Sankyo

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                            Lead Product(s) : Datopotamab Deruxtecan

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : AstraZeneca

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            DATROWAY Approved in EU for HER2- Breast Cancer After Prior Treatment

                            Details : Datroway (datopotamab deruxtecan) is a specifically engineered TROP2 directed DXd ADC, approved for adults with unresectable or metastatic HR positive, HER2 negative breast cancer.

                            Product Name : Datroway

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            April 08, 2025

                            Lead Product(s) : Datopotamab Deruxtecan

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : AstraZeneca

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Daiichi Sankyo

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                            APGA Annual Conference
                            Not Confirmed

                            Daiichi Sankyo

                            Japan arrow
                            APGA Annual Conference
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Trastuzumab Deruxtecan

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Recipient : AstraZeneca

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ENHERTU Approved in the EU as First HER2 Directed Therapy for Breast Cancer

                            Details : Enhertu (trastuzumab deruxtecan) is a HER2-directed ADC which is being evaluated for the treatment of previously treated patients with HR positive, HER2 low metastatic breast cancer.

                            Product Name : Enhertu

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            April 04, 2025

                            Lead Product(s) : Trastuzumab Deruxtecan

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Recipient : AstraZeneca

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Daiichi Sankyo

                            Japan arrow
                            APGA Annual Conference
                            Not Confirmed

                            Daiichi Sankyo

                            Japan arrow
                            APGA Annual Conference
                            Not Confirmed
                            • fda
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                            • WHO-GMP
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                            Lead Product(s) : Trastuzumab Deruxtecan,Cisplatin,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Merck & Co

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Enhertu Initiated in Patients with Previously Untreated HER2 Positive Gastric Cancer

                            Details : Enhertu (trastuzumab deruxtecan) in combination with fluoropyrimidine chemotherapy, pembrolizumab is being studied for unresectable, locally advanced or metastatic HER2 positive gastric or GEJ cancer.

                            Product Name : Enhertu

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            March 31, 2025

                            Lead Product(s) : Trastuzumab Deruxtecan,Cisplatin,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Merck & Co

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Daiichi Sankyo

                            Japan arrow
                            APGA Annual Conference
                            Not Confirmed

                            Daiichi Sankyo

                            Japan arrow
                            APGA Annual Conference
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Datopotamab Deruxtecan

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : AstraZeneca

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            CHMP Recommends Datopotamab Deruxtecan for HR+/HER2- Breast Cancer

                            Details : Datroway (datopotamab deruxtecan) is a specifically engineered TROP2 directed DXd ADC, approved for adults with unresectable or metastatic HR positive, HER2 negative breast cancer.

                            Product Name : Datroway

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            January 31, 2025

                            Lead Product(s) : Datopotamab Deruxtecan

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : AstraZeneca

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Daiichi Sankyo

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                            APGA Annual Conference
                            Not Confirmed

                            Daiichi Sankyo

                            Japan arrow
                            APGA Annual Conference
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Datopotamab Deruxtecan,Rilvegostomig

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : AstraZeneca

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Datroway Phase 3 Begins for NSCLC Patients at High Relapse Risk

                            Details : Datroway (datopotamab deruxtecan), an TROP2 ADC, plus rilvegostomig, A PD-1/TIGIT bispecific antibody, is being investigated in patients with stage 1 adenocarcinoma non-small cell lung cancer.

                            Product Name : Datroway

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            January 30, 2025

                            Lead Product(s) : Datopotamab Deruxtecan,Rilvegostomig

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : AstraZeneca

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Daiichi Sankyo

                            Japan arrow
                            APGA Annual Conference
                            Not Confirmed

                            Daiichi Sankyo

                            Japan arrow
                            APGA Annual Conference
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Datopotamab Deruxtecan

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : AstraZeneca

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            DATROWAY® Approved in U.S. for Metastatic HR+ HER2- Breast Cancer

                            Details : Datroway (datopotamab deruxtecan) is a specifically engineered TROP2 directed DXd ADC, approved in the U.S. for adults with unresectable or metastatic HR positive, HER2 negative breast cancer.

                            Product Name : Datroway

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            January 17, 2025

                            Lead Product(s) : Datopotamab Deruxtecan

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : AstraZeneca

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Daiichi Sankyo

                            Japan arrow
                            APGA Annual Conference
                            Not Confirmed

                            Daiichi Sankyo

                            Japan arrow
                            APGA Annual Conference
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Datopotamab Deruxtecan

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Datopotamab Deruxtecan Gets Priority Review for EGFR-Mutated NSCLC

                            Details : Dato-DXd (datopotamab deruxtecan) is a DNA topoisomerase I inhibitor candidate, which is being developed in patients with EGFR-mutated non-small cell lung cancer.

                            Product Name : Dato-DXd

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            January 13, 2025

                            Lead Product(s) : Datopotamab Deruxtecan

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Daiichi Sankyo

                            Japan arrow
                            APGA Annual Conference
                            Not Confirmed

                            Daiichi Sankyo

                            Japan arrow
                            APGA Annual Conference
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Quizartinib,Cytarabine,Daunorubicin

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            QuANTUM-Wild Phase 3 Trial of VANFLYTA® Begins in FLT3-ITD Negative AML

                            Details : VANFLYTA® (quizartinib) is an oral, highly potent, type II FLT3 inhibitor that selectively targets FLT3-ITD mutations and has been specifically developed for patients with FLT3-ITD positive AML.

                            Product Name : Vanflyta

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 10, 2024

                            Lead Product(s) : Quizartinib,Cytarabine,Daunorubicin

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Daiichi Sankyo

                            Japan arrow
                            APGA Annual Conference
                            Not Confirmed

                            Daiichi Sankyo

                            Japan arrow
                            APGA Annual Conference
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Datopotamab Deruxtecan

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : AstraZeneca

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Datopotamab Deruxtecan Gets Breakthrough Therapy Designation for EGFR-Mutated NSCLC

                            Details : Dato-DXd (datopotamab deruxtecan) is a DNA topoisomerase I inhibitor candidate, which is being developed in patients with EGFR-mutated non-small cell lung cancer.

                            Product Name : Dato-DXd

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            December 09, 2024

                            Lead Product(s) : Datopotamab Deruxtecan

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : AstraZeneca

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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