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Drug","year":"2021","type":"Inapplicable","leadProduct":"Cyclophosphamide","moa":"DNA","graph1":"Oncology","graph2":"Phase I","graph3":"Second Affiliated Hospital, Zhejiang University","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Second Affiliated Hospital, Zhejiang University \/ Carbiogene Therapeutics","highestDevelopmentStatusID":"6","companyTruncated":"Second Affiliated Hospital, Zhejiang University \/ Carbiogene Therapeutics"},{"orgOrder":0,"company":"Ossium Health","sponsor":"Center for International Blood and Marrow Transplant Research","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cytotoxic Drug","year":"2021","type":"Inapplicable","leadProduct":"Cyclophosphamide","moa":"DNA","graph1":"Oncology","graph2":"Phase I","graph3":"Ossium Health","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Ossium Health \/ Center for International Blood and Marrow Transplant Research","highestDevelopmentStatusID":"6","companyTruncated":"Ossium Health \/ Center for International Blood and Marrow Transplant Research"},{"orgOrder":0,"company":"Richard Wu","sponsor":"Iovance Biotherapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Cytotoxic Drug","year":"2022","type":"Inapplicable","leadProduct":"Cyclophosphamide","moa":"DNA","graph1":"Oncology","graph2":"Phase I","graph3":"Richard Wu","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Richard Wu \/ Iovance Biotherapeutics","highestDevelopmentStatusID":"6","companyTruncated":"Richard Wu \/ Iovance Biotherapeutics"},{"orgOrder":0,"company":"Fred Hutchinson Cancer Center","sponsor":"Nektar Therapeutics","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cytotoxic Drug","year":"2022","type":"Inapplicable","leadProduct":"Cyclophosphamide","moa":"DNA","graph1":"Oncology","graph2":"Phase I","graph3":"Fred Hutchinson Cancer Center","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Fred Hutchinson Cancer Center \/ Nektar Therapeutics","highestDevelopmentStatusID":"6","companyTruncated":"Fred Hutchinson Cancer Center \/ Nektar Therapeutics"},{"orgOrder":0,"company":"Acepodia","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"TAIWAN","productType":"Cytotoxic Drug","year":"2022","type":"Inapplicable","leadProduct":"Cyclophosphamide","moa":"DNA","graph1":"Oncology","graph2":"Phase I","graph3":"Acepodia","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Acepodia \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Acepodia \/ Inapplicable"},{"orgOrder":0,"company":"Hospital Israelita Albert Einstein","sponsor":"Miltenyi Biotec","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Cytotoxic Drug","year":"2023","type":"Inapplicable","leadProduct":"Cyclophosphamide","moa":"DNA","graph1":"Oncology","graph2":"Phase I","graph3":"Hospital Israelita Albert Einstein","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hospital Israelita Albert Einstein \/ Miltenyi Biotec","highestDevelopmentStatusID":"6","companyTruncated":"Hospital Israelita Albert Einstein \/ Miltenyi Biotec"},{"orgOrder":0,"company":"Elvira Umyarova","sponsor":"Sanofi","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Cytotoxic Drug","year":"2024","type":"Inapplicable","leadProduct":"Cyclophosphamide","moa":"DNA","graph1":"Oncology","graph2":"Phase I","graph3":"Elvira Umyarova","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Elvira Umyarova \/ Sanofi","highestDevelopmentStatusID":"6","companyTruncated":"Elvira Umyarova \/ Sanofi"},{"orgOrder":0,"company":"Acepodia","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"TAIWAN","productType":"Cytotoxic Drug","year":"2024","type":"Inapplicable","leadProduct":"Cyclophosphamide","moa":"DNA","graph1":"Oncology","graph2":"Phase I","graph3":"Acepodia","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Acepodia \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Acepodia \/ Inapplicable"},{"orgOrder":0,"company":"Therapeutic Solutions","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2021","type":"Inapplicable","leadProduct":"Cyclophosphamide","moa":"||Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Therapeutic Solutions","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Therapeutic Solutions \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Therapeutic Solutions \/ Inapplicable"},{"orgOrder":0,"company":"Providence Health & Services","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Cytotoxic Drug","year":"2022","type":"Inapplicable","leadProduct":"Cyclophosphamide","moa":"DNA","graph1":"Oncology","graph2":"Undisclosed","graph3":"Providence Health & Services","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Providence Health & Services \/ Inapplicable","highestDevelopmentStatusID":"1","companyTruncated":"Providence Health & Services \/ Inapplicable"},{"orgOrder":0,"company":"University of Washington","sponsor":"AbbVie Inc","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Cytotoxic Drug","year":"2025","type":"Inapplicable","leadProduct":"Cyclophosphamide","moa":"DNA","graph1":"Oncology","graph2":"Phase II","graph3":"University of Washington","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"University of Washington \/ AbbVie Inc","highestDevelopmentStatusID":"8","companyTruncated":"University of Washington \/ AbbVie Inc"},{"orgOrder":0,"company":"Anocca","sponsor":"Mellby Gard","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"SWEDEN","productType":"Cell and Gene therapy","year":"2025","type":"Financing","leadProduct":"ANOC-001","moa":"||KRAS G12V","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Anocca","amount2":0.050000000000000003,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0.050000000000000003,"dosageForm":"Infusion","sponsorNew":"Anocca \/ Mellby Gard","highestDevelopmentStatusID":"7","companyTruncated":"Anocca \/ Mellby Gard"}]

    Find Clinical Drug Pipeline Developments & Deals for (-)-Cyclophosphamide

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    (-)-Cyclophosphamide

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                            01

                            AbbVie Inc

                            U.S.A
                            World Drug Safety EU
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Epcoritamab,Cyclophosphamide,Rituximab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Two Data Analyses Show Epcoritamab Induces Durable Complete Responses

                            Details : Tepkinly (epcoritamab) is an IgG1-bispecific antibody, which is evaluated for the treatment of diffuse large B-cell lymphoma. It is designed to direct cytotoxic T cells selectively.

                            Product Name : Tepkinly

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            December 09, 2024

                            Lead Product(s) : Epcoritamab,Cyclophosphamide,Rituximab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            NanoAlvand

                            Iran
                            CPhI WW Frankfurt
                            Attending
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Cyclophosphamide

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Endoxyna®; A Crucial Medication with A Novel Solution Formulation

                            Details : Endoxyna is a novel liquid formulation of cyclophosphamide, to replace the previous freeze-dried products. It is indicated for the treatment of cancer

                            Product Name : Endoxyna

                            Product Type : Cytotoxic Drug

                            Upfront Cash : Inapplicable

                            June 29, 2024

                            Lead Product(s) : Cyclophosphamide

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            AbbVie Inc

                            U.S.A
                            World Drug Safety EU
                            Not Confirmed
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                            • WHO-GMP
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                            Lead Product(s) : Cyclophosphamide

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : GBG Forschungs GmbH | NSABP Foundation | Grupo Español de Investigación del Cáncer de Mama | US Oncology Research

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study Evaluating Safety and Efficacy of the Addition of ABT-888 Plus Carboplatin Versus the Addition of Carb...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Cytotoxic Drug

                            Upfront Cash : Inapplicable

                            January 10, 2014

                            Lead Product(s) : Cyclophosphamide

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : GBG Forschungs GmbH | NSABP Foundation | Grupo Español de Investigación del Cáncer de Mama | US Oncology Research

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            KSQ Therapeutics

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                            World Drug Safety EU
                            Not Confirmed

                            KSQ Therapeutics

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                            World Drug Safety EU
                            Not Confirmed
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                            • WHO-GMP
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                            Lead Product(s) : KSQ-004EX,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            KSQ Doses First Patient with CRISPR-Based KSQ-004EX eTIL Therapy

                            Details : KSQ-004EX, an eTIL cell therapy in which TIL are edited to inactivate the genes encoding SOCS1 and Regnase-1, is being evaluated for the treatment of advanced solid tumor.

                            Product Name : Undisclosed

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            April 09, 2025

                            Lead Product(s) : KSQ-004EX,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Universität Münster

                            Country arrow
                            World Drug Safety EU
                            Not Confirmed

                            Universität Münster

                            Country arrow
                            World Drug Safety EU
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Cyclophosphamide

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Kite Pharma

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Axicabtagene Ciloleucel CAR T-cells in Patients With Relapsed or Refractory Primary Mediastinal B-cell Lymphom...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Cytotoxic Drug

                            Upfront Cash : Inapplicable

                            April 04, 2025

                            Lead Product(s) : Cyclophosphamide

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Kite Pharma

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            CEL-SCI

                            U.S.A arrow
                            World Drug Safety EU
                            Not Confirmed

                            CEL-SCI

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                            World Drug Safety EU
                            Not Confirmed
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                            • WHO-GMP
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                            Lead Product(s) : Interleukin 2,Cisplatin,Cyclophosphamide

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Thinkequity

                            Deal Size : $2.5 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            CEL-SCI Announces Closing of $2.5 Million Offering

                            Details : The net proceeds from the offering will used to fund the development of Multikine (leukocyte interleukin) for treatment of patients suffering from stage III/IV squamous cell carcinoma of head & neck.

                            Product Name : Multikine

                            Product Type : Protein

                            Upfront Cash : Undisclosed

                            March 18, 2025

                            Lead Product(s) : Interleukin 2,Cisplatin,Cyclophosphamide

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Thinkequity

                            Deal Size : $2.5 million

                            Deal Type : Public Offering

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                            07

                            Bristol Myers Squibb

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                            World Drug Safety EU
                            Not Confirmed

                            Bristol Myers Squibb

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                            World Drug Safety EU
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Lisocabtagene Maraleucel,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            BMS Wins EU Approval to Expand CAR T Breyanzi for Relapsed Follicular Lymphoma

                            Details : Breyanzi (lisocabtagene maraleucel) is a CD19-directed CAR T cell therapy, recieved EMA approval for relapsed or refractory folicular lymphoma in adults.

                            Product Name : Breyanzi

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            March 14, 2025

                            Lead Product(s) : Lisocabtagene Maraleucel,Cyclophosphamide,Fludarabine Phosphate

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            CEL-SCI

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                            World Drug Safety EU
                            Not Confirmed

                            CEL-SCI

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                            World Drug Safety EU
                            Not Confirmed
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                            • WHO-GMP
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                            Lead Product(s) : Interleukin 2,Cyclophosphamide,Indomethacin

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            CEL-SCI to Initiate Multikine Confirmatory Phase 3 Cancer Trial

                            Details : Multikine (leukocyte interleukin) is being evaluated for treatment of patients suffering from stage III/IV squamous cell carcinoma of head and neck.

                            Product Name : Multikine

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            February 20, 2025

                            Lead Product(s) : Interleukin 2,Cyclophosphamide,Indomethacin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            CEL-SCI

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                            World Drug Safety EU
                            Not Confirmed

                            CEL-SCI

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                            World Drug Safety EU
                            Not Confirmed
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                            • WHO-GMP
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                            Lead Product(s) : Interleukin 2,Cyclophosphamide,Indomethacin

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Thinkequity

                            Deal Size : $5.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            CEL-SCI Announces Closing of $5 Million Offering

                            Details : The Company intends to use the net proceeds from the offering to fund the continued development of Multikine (leukocyte interleukin) for treatment of Squamous Cell Carcinoma of Head and Neck.

                            Product Name : Multikine

                            Product Type : Protein

                            Upfront Cash : Undisclosed

                            December 31, 2024

                            Lead Product(s) : Interleukin 2,Cyclophosphamide,Indomethacin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Thinkequity

                            Deal Size : $5.0 million

                            Deal Type : Public Offering

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                            10

                            CEL-SCI

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                            World Drug Safety EU
                            Not Confirmed

                            CEL-SCI

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                            World Drug Safety EU
                            Not Confirmed
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                            • WHO-GMP
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                            Lead Product(s) : Interleukin 2,Cyclophosphamide,Indomethacin

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Thinkequity

                            Deal Size : $5.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            CEL-SCI Announces Pricing of $5 Million Public Offering

                            Details : The Company intends to use the net proceeds from the offering to fund the continued development of Multikine (leukocyte interleukin) for treatment of Squamous Cell Carcinoma of Head and Neck.

                            Product Name : Multikine

                            Product Type : Protein

                            Upfront Cash : Undisclosed

                            December 29, 2024

                            Lead Product(s) : Interleukin 2,Cyclophosphamide,Indomethacin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Thinkequity

                            Deal Size : $5.0 million

                            Deal Type : Public Offering

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