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            Development Status

            Details:

            The proceeds will be used to advance CPTX2309, Capstan’s lead in vivo chimeric antigen receptor T cell (CAR-T) candidate, to early clinical proof-of-concept in autoimmune disorders, and to further develop Capstan’s tLNP pipeline.

            Lead Product(s): CPTX2309

            Therapeutic Area: Immunology Product Name: CPTX2309

            Highest Development Status: Preclinical Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: RA Capital Management

            Deal Size: $175.0 million Upfront Cash: Undisclosed

            Deal Type: Series B Financing March 20, 2024

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            Details:

            Capstan’s modular platform leverages the biological and technological expertise of its founding scientists and includes proprietary targeted lipid nanoparticles (tLNP) technology.

            Lead Product(s): tLNP-medicated In-vivo CAR-T Cell Therapy

            Therapeutic Area: Oncology Product Name: Undisclosed

            Highest Development Status: Preclinical Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: Novartis Venture Fund

            Deal Size: $63.0 million Upfront Cash: Undisclosed

            Deal Type: Financing September 14, 2022

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            The company plans to use the funds to further its mission of advancing the clinical promise of cell-based therapies by enabling precise in vivo engineering of cells with payloads necessary to benefit patients across multiple disease categories.

            Lead Product(s): tLNP-medicated In-vivo CAR-T Cell Therapy

            Therapeutic Area: Oncology Product Name: Undisclosed

            Highest Development Status: Preclinical Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: Pfizer Ventures

            Deal Size: $102.0 million Upfront Cash: Undisclosed

            Deal Type: Series A Financing September 14, 2022

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