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Pegol","moa":"TNF-alpha","graph1":"Immunology","graph2":"Preclinical","graph3":"Biogen","amount2":0.089999999999999997,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0.089999999999999997,"dosageForm":"Undisclosed","sponsorNew":"Biogen \/ Biogen","highestDevelopmentStatusID":"4","companyTruncated":"Biogen \/ Biogen"},{"orgOrder":0,"company":"Biogen","sponsor":"Sangamo Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2020","type":"Collaboration","leadProduct":"ST-501","moa":"Tau aggregation","graph1":"Neurology","graph2":"Preclinical","graph3":"Biogen","amount2":2.7200000000000002,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":2.7200000000000002,"dosageForm":"Undisclosed","sponsorNew":"Biogen \/ Biogen","highestDevelopmentStatusID":"4","companyTruncated":"Biogen \/ Biogen"},{"orgOrder":0,"company":"Biogen","sponsor":"Ionis Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Oligonucleotide","year":"2022","type":"Licensing Agreement","leadProduct":"BIIB115","moa":"SMN1 messenger RNA (SMN1 mRNA)","graph1":"Genetic Disease","graph2":"Preclinical","graph3":"Biogen","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Biogen \/ Biogen","highestDevelopmentStatusID":"4","companyTruncated":"Biogen \/ Biogen"},{"orgOrder":0,"company":"Biogen","sponsor":"ISD Immunotech","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"DENMARK","productType":"Peptide","year":"2020","type":"Collaboration","leadProduct":"ISD017","moa":"STING","graph1":"Immunology","graph2":"Preclinical","graph3":"Biogen","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Biogen \/ Biogen","highestDevelopmentStatusID":"4","companyTruncated":"Biogen \/ Biogen"},{"orgOrder":0,"company":"Biogen","sponsor":"Massachusetts Eye And Ear","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Undisclosed","year":"2020","type":"Agreement","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Genetic Disease","graph2":"Preclinical","graph3":"Biogen","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Biogen \/ Massachusetts Eye And Ear","highestDevelopmentStatusID":"4","companyTruncated":"Biogen \/ Massachusetts Eye And Ear"},{"orgOrder":0,"company":"Biogen","sponsor":"City Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Undisclosed","year":"2025","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Neurology","graph2":"Preclinical","graph3":"Biogen","amount2":1.05,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":1.05,"dosageForm":"Undisclosed","sponsorNew":"Biogen \/ Biogen","highestDevelopmentStatusID":"4","companyTruncated":"Biogen \/ Biogen"}]

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                            01

                            Biogen

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Recipient : City Therapeutics

                            Deal Size : $1,046.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Biogen and City Therapeutics Partner On RNAi-Based Therapy Development

                            Details : Through the collaboration, City will leverage its next-generation RNAi engineering technologies to develop an RNAi trigger molecule combined with proprietary drug delivery technology from Biogen.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : $16.0 million

                            May 27, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Recipient : City Therapeutics

                            Deal Size : $1,046.0 million

                            Deal Type : Collaboration

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                            02

                            Biogen

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                            Lead Product(s) : Omaveloxolone

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study to Learn More About the Effects and Long-Term Safety of BIIB141 (Omaveloxolone) in Participants With F...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 01, 2025

                            Lead Product(s) : Omaveloxolone

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Biogen

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                            Lead Product(s) : BIIB080

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Ionis Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Biogen’s BIIB080 Gets FDA Fast Track for Tau-Targeting Alzheimer’s Therapy

                            Details : BIIB080 is an investigational antisense oligonucleotide (ASO) therapy designed to target microtubule-associated protein tau (MAPT) mRNA to reduce the production of tau protein.

                            Product Name : IONIS-MAPTRx

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            April 02, 2025

                            Lead Product(s) : BIIB080

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Ionis Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Biogen

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                            ChemOutsourcing
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                            Biogen

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                            Lead Product(s) : Zorevunersen Sodium

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Recipient : Stoke Therapeutics

                            Deal Size : $550.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Biogen and Stoke Therapeutics Enter into Collaboration to Develop Zorevunersen

                            Details : The collaboration aims to support the development and commercialization of STK-001 (zorevunersen sodium), a potential first-in-class disease modifying medicine for the treatment of Dravet syndrome.

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : $165.0 million

                            February 18, 2025

                            Lead Product(s) : Zorevunersen Sodium

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Recipient : Stoke Therapeutics

                            Deal Size : $550.0 million

                            Deal Type : Collaboration

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                            05

                            Biogen

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                            Biogen

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                            Lead Product(s) : Aflibercept

                            Therapeutic Area : Ophthalmology

                            Study Phase : Approved FDF

                            Recipient : Samsung Bioepis

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Samsung/Biogen EC Nod for OPUVIZ™ Aflibercept Biosimilar

                            Details : Opuviz (aflibercept) is a vascular endothelial growth factor (VEGF) inhibitor indicated for the treatment of patients with Neovascular (Wet) Age-Related Macular Degeneration

                            Product Name : Opuviz

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            November 18, 2024

                            Lead Product(s) : Aflibercept

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Approved FDF

                            Recipient : Samsung Bioepis

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Biogen

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Discovery Platform

                            Recipient : AbCellera

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            AbCellera Collaborates with Biogen to Discover Antibodies for Neurological Conditions

                            Details : The collaboration aims to discover antibodies for a novel target that enables the delivery of biotherapeutics to the brain for indications in neuroscience.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            November 03, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Discovery Platform

                            Recipient : AbCellera

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            07

                            Biogen

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Discovery Platform

                            Recipient : Neomorph

                            Deal Size : $1,450.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Biogen & Neomorph Announce Collaboration to Discover and Develop Molecular Glue Degraders

                            Details : The collaboration aims to leverage Neomorph's proprietary molecular glue discovery platform to expedite the identification and validation of new small-molecule therapeutics for Alzheimer’s disease.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            October 29, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Discovery Platform

                            Recipient : Neomorph

                            Deal Size : $1,450.0 million

                            Deal Type : Collaboration

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                            08

                            Biogen

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                            Biogen

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Study Phase : Discovery

                            Recipient : C4 Therapeutics

                            Deal Size : $415.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            C4 Therapeutics Announces Delivery of Second Development Candidate to Biogen

                            Details : The collaboration aims to investigate the use of C4T’s novel protein degradation platform to discover and develop potential new treatments for Alzheimer’s & Parkinson’s disease.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            October 09, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Neurology

                            Highest Development Status : Discovery

                            Recipient : C4 Therapeutics

                            Deal Size : $415.0 million

                            Deal Type : Collaboration

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                            09

                            Biogen

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                            Biogen

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                            Lead Product(s) : Dapirolizumab Pegol

                            Therapeutic Area : Immunology

                            Study Phase : Phase III

                            Recipient : UCB Pharma S.A

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            UCB and Biogen Announce Positive Phase 3 Results for Dapirolizumab Pegol in Lupus

                            Details : CDP7657 (dapirolizumab pegol), a novel Fc-free anti-CD40L drug candidate, investigated in people living with moderate-to-severe systemic lupus erythematosus (SLE).

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            September 24, 2024

                            Lead Product(s) : Dapirolizumab Pegol

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase III

                            Recipient : UCB Pharma S.A

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Biogen

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                            Biogen

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                            Lead Product(s) : Aflibercept

                            Therapeutic Area : Ophthalmology

                            Study Phase : Approved FDF

                            Recipient : Samsung Bioepis

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Samsung Bioepis and Biogen Receive CHMP Opinion for OPUVIZ™ Biosimilar

                            Details : Opuviz (aflibercept) is a vascular endothelial growth factor (VEGF) inhibitor indicated for the treatment of patients with Neovascular (Wet) Age-Related Macular Degeneration

                            Product Name : Opuviz

                            Product Type : Protein

                            Upfront Cash : Inapplicable

                            September 20, 2024

                            Lead Product(s) : Aflibercept

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Approved FDF

                            Recipient : Samsung Bioepis

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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