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    [{"orgOrder":0,"company":"Bayer AG","sponsor":"WuXi Biologics","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"Undisclosed","newsHeadline":"WuXi Biologics and Bayer enter into acquisition agreement","therapeuticArea":"Genetic Disease","highestDevelopmentStatus":"Approved","country":"GERMANY","productType":"Large molecule","productStatus":"Approved","date":"January 2020","url1":"","url2":"","graph1":"Genetic Disease","graph2":"Approved"},{"orgOrder":0,"company":"Bayer AG","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Bayer and Azitra Partner to Harness the Human Skin Microbiome as a Source for New Natural Skin Care Products for Sensitive and Eczema-Prone Skin","therapeuticArea":"Dermatology","highestDevelopmentStatus":"Preclinical","country":"GERMANY","productType":"Large molecule","productStatus":"Approved","date":"January 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AG","sponsor":"AskBio","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"First Patient Randomized in AskBio Phase II Gene Therapy Trial for Congestive Heart Failure","therapeuticArea":"Cardiology\/Vascular Diseases","highestDevelopmentStatus":"Phase II","country":"GERMANY","productType":"Cell and Gene therapy","productStatus":"New Molecular Entity","date":"February 2024","url1":"","url2":"","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase II"},{"orgOrder":0,"company":"BlueRock Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"BlueRock Therapeutics Phase I Clinical Trial for Parkinson\u2019s Disease Continues to Show Positive Trends at 18 Months","therapeuticArea":"Neurology","highestDevelopmentStatus":"Phase I","country":"U.S.A","productType":"Cell and Gene therapy","productStatus":"New Molecular Entity","date":"March 2024","url1":"","url2":"","graph1":"Neurology","graph2":"Phase I"},{"orgOrder":0,"company":"Bayer AG","sponsor":"Dr. Reddy's Laboratories","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"Undisclosed","newsHeadline":"Bayer and Dr. Reddy\u2019s sign a marketing and distribution agreement for second brand of Vericiguat\u2122 in India","therapeuticArea":"Cardiology\/Vascular Diseases","highestDevelopmentStatus":"Approved","country":"GERMANY","productType":"Small molecule","productStatus":"Approved","date":"April 2024","url1":"","url2":"","graph1":"Cardiology\/Vascular Diseases","graph2":"Approved"}]

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              Bayer AG

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              Bayer and Thermo Fisher Scientific Collaborate to Increase Patient Access to Precision Cancer Medicines

              Details:

              The collaboration aims to develop next-generation sequencing-based companion diagnostic assays to identify patients who may benefit from Bayer’s portfolio of precision cancer therapies, including Nubeqa (darolutamide), a medication for certain prostate cancers (mHSPC, nmCRPC).

              Lead Product(s): Darolutamide

              Therapeutic Area: Oncology Product Name: Nubeqa

              Highest Development Status: Phase III Product Type: Small molecule

              Recipient: Thermo Fisher Scientific

              Deal Size: Undisclosed Upfront Cash: Undisclosed

              Deal Type: Collaboration March 20, 2024

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              Bayer AG

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              Positive Topline Results from Phase III Long-Term Study OASIS 3 Support Submissions for Marketing Authorization for Bayer’s Elinzanetant

              Details:

              BAY3427080 (elinzanetant) is the first dual neurokinin-1,3 (NK-1,3) receptor antagonist, which is being evaluated for the treatment of moderate to severe vasomotor symptoms (VMS, also known as hot flashes.

              Lead Product(s): Elinzanetant

              Therapeutic Area: Obstetrics/Gynecology (Women’s Health) Product Name: BAY3427080

              Highest Development Status: Phase III Product Type: Small molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable March 19, 2024

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              BlueRock Therapeutics

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              BlueRock Therapeutics Phase I Clinical Trial for Parkinson’s Disease Continues to Show Positive Trends at 18 Months

              Details:

              Bemdaneprocel (BRT-DA01) is an investigational allogeneic stem cell derived cell therapy designed to replace the dopamine producing neurons that are lost in Parkinson’s disease.

              Lead Product(s): Bemdaneprocel

              Therapeutic Area: Neurology Product Name: BRT-DA01

              Highest Development Status: Phase I Product Type: Cell and Gene therapy

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable March 06, 2024

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              Bayer AG

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              BridgeBio Pharma and Bayer Announce European Licensing Agreement for Acoramidis in ATTR-CM

              Details:

              Under the agreement, BridgeBio grants Bayer exclusive license to commercialize acoramidis, an investigational, next-generation, orally-administered, highly potent small molecule stabilizer of TTR, as a treatment for patients with ATTR-CM in Europe.

              Lead Product(s): Acoramidis Hydrochloride

              Therapeutic Area: Genetic Disease Product Name: AG10

              Highest Development Status: Phase III Product Type: Small molecule

              Recipient: BridgeBio Pharma

              Deal Size: Undisclosed Upfront Cash: $310.0 million

              Deal Type: Licensing Agreement March 04, 2024

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              Bayer AG

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              Bayer Receives U.S. FDA Breakthrough Therapy Designation for BAY 2927088 for Non-Small Cell Lung Cancer Harboring HER2 Activating Mutations

              Details:

              BAY 2927088 is an oral, small molecule tyrosine kinase inhibitor, which is being evaluated for the treatment of non-small cell lung cancer harboring HER2 activating mutations.

              Lead Product(s): BAY2927088

              Therapeutic Area: Oncology Product Name: BAY2927088

              Highest Development Status: Phase I/ Phase II Product Type: Small molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable February 26, 2024

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              Bayer AG

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              First Patient Randomized in AskBio Phase II Gene Therapy Trial for Congestive Heart Failure

              Details:

              AB-1002 (NAN-101) is an investigational gene therapy, which is currently under phase 2 clinical development for the treatment of congestive heart failure.

              Lead Product(s): NAN-101

              Therapeutic Area: Cardiology/Vascular Diseases Product Name: AB-1002

              Highest Development Status: Phase II Product Type: Cell and Gene therapy

              Recipient: AskBio

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable February 16, 2024

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              Bayer AG

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              Application for Regulatory Approval of Aflibercept 8 mg Accepted in China

              Details:

              Eylea (aflibercept) is a PGF & VEGF-A inhibitor, It is being evaluated in phase 3 clinical trials for the treatment of neovascular (wet) age-related macular degeneration.

              Lead Product(s): Aflibercept

              Therapeutic Area: Ophthalmology Product Name: Eylea

              Highest Development Status: Approved Product Type: Large molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable January 24, 2024

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              BlueRock Therapeutics

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              BlueRock Therapeutics Exercises Exclusive Option to License IPSC Cell Therapy Candidate OpCT-001 for Treating Primary Photoreceptor Diseases from FUJIFILM Cellular Dynamics...

              Details:

              Under the agreement, BlueRock exercised its option to exclusively license OpCT-001, an induced pluripotent stem cell (iPSC) derived cell therapy candidate for the treatment of primary photoreceptor diseases.

              Lead Product(s): OpCT-001

              Therapeutic Area: Genetic Disease Product Name: OpCT-001

              Highest Development Status: Preclinical Product Type: Cell and Gene therapy

              Recipient: Fujifilm Cellular Dynamics

              Deal Size: Undisclosed Upfront Cash: Undisclosed

              Deal Type: Licensing Agreement January 23, 2024

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              Bayer AG

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              New Eylea™ 8 mg Approved in Japan

              Details:

              Eylea (aflibercept) is a PGF & VEGF-A inhibitor, It is now approved in Japan for the treatment of neovascular (wet) age-related macular degeneration & diabetic macular edema.

              Lead Product(s): Aflibercept

              Therapeutic Area: Ophthalmology Product Name: Eylea

              Highest Development Status: Approved Product Type: Large molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable January 18, 2024

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              Bayer AG

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              Bayer’s AskBio Initiates Phase II GenePHIT Trial in Congestive Heart Failure (CHF)

              Details:

              NAN-101 (AB-1002) is a novel DUSP1 inhibitor which is currently being evaluated in phase 2 clinical trials for the treatment of congestive heart failure.

              Lead Product(s): AB-1002

              Therapeutic Area: Cardiology/Vascular Diseases Product Name: NAN-101

              Highest Development Status: Phase II Product Type: Cell and Gene therapy

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable January 11, 2024

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              Minakem offers CDMO services for API & HPAPI, generics, regulatory expertise, track record performance & FDA & GMP certifications.
              ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.
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