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    [{"orgOrder":0,"company":"Amgen Inc","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Avacopan","moa":"||C5a receptor","graph1":"Immunology","graph2":"Approved FDF","graph3":"Amgen Inc","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Amgen Inc \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Amgen Inc \/ Inapplicable"},{"orgOrder":0,"company":"Amgen Inc","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Avacopan","moa":"||C5a receptor","graph1":"Immunology","graph2":"Approved FDF","graph3":"Amgen Inc","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Amgen Inc \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Amgen Inc \/ Inapplicable"},{"orgOrder":0,"company":"CSL","sponsor":"Amgen Inc","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"AUSTRALIA","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Avacopan","moa":"||C5a receptor","graph1":"Immunology","graph2":"Approved FDF","graph3":"CSL","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"CSL \/ Amgen Inc","highestDevelopmentStatusID":"15","companyTruncated":"CSL \/ Amgen Inc"},{"orgOrder":0,"company":"F. Hoffmann-La Roche","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rare Diseases and Disorders","country":"SWITZERLAND","productType":"Antibody","year":"2021","type":"Inapplicable","leadProduct":"Azathioprine","moa":"||IL-6-alpha receptor","graph1":"Rare Diseases and Disorders","graph2":"Approved FDF","graph3":"F. Hoffmann-La Roche","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Rare Diseases","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"F. Hoffmann-La Roche \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"F. Hoffmann-La Roche \/ Inapplicable"},{"orgOrder":0,"company":"Chinese SLE Treatment And Research Group","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Azathioprine","moa":"DNA | Amidophosphoribosyltransferase","graph1":"Immunology","graph2":"Phase IV","graph3":"Chinese SLE Treatment And Research Group","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Chinese SLE Treatment And Research Group \/ Inapplicable","highestDevelopmentStatusID":"11","companyTruncated":"Chinese SLE Treatment And Research Group \/ Inapplicable"},{"orgOrder":0,"company":"Nantes University Hospital","sponsor":"Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Azathioprine","moa":"DNA | Amidophosphoribosyltransferase","graph1":"Immunology","graph2":"Undisclosed","graph3":"Nantes University Hospital","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Nantes University Hospital \/ Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives","highestDevelopmentStatusID":"1","companyTruncated":"Nantes University Hospital \/ Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives"}]

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                            01

                            Chinese SLE Treatment And Research Group

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                            EPSC
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                            Chinese SLE Treatment And Research Group

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                            Lead Product(s) : Azathioprine

                            Therapeutic Area : Immunology

                            Study Phase : Phase IV

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Efficacy and Safety for Telitacicept in the Remission Maintenance Treatment of ANCA-associated Vasculitis (TTC...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 28, 2023

                            Lead Product(s) : Azathioprine

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase IV

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Nantes University Hospital

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                            EPSC
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                            Nantes University Hospital

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                            EPSC
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                            Lead Product(s) : Azathioprine

                            Therapeutic Area : Immunology

                            Study Phase : Undisclosed

                            Sponsor : Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Medical Treatment Versus Surgery in Stricturing Small Bowel Crohn's Disease

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 18, 2022

                            Lead Product(s) : Azathioprine

                            Therapeutic Area : Immunology

                            Highest Development Status : Undisclosed

                            Sponsor : Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            F. Hoffmann-La Roche

                            Switzerland arrow
                            EPSC
                            Not Confirmed

                            F. Hoffmann-La Roche

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                            EPSC
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                            Lead Product(s) : Satralizumab,Azathioprine,Mycophenolate Mofetil

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Roche’s Enspryng Leads Latest CHMP Recommendations

                            Details : Leading those recommendations is Roche’s Enspryng (satralizumab), which received a positive opinion for the treatment of the rare autoimmune disease neuromyelitis optica spectrum disorders (NMOSD).

                            Product Name : Enspryng

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            April 23, 2021

                            Lead Product(s) : Satralizumab,Azathioprine,Mycophenolate Mofetil

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Amgen Inc

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                            EPSC
                            Not Confirmed

                            Amgen Inc

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                            Lead Product(s) : Avacopan,Azathioprine,Rituximab

                            Therapeutic Area : Immunology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ChemoCentryx Announces FDA Acceptance of the Avacopan New Drug Application (NDA) for the Treatment of ANCA-Ass...

                            Details : The NDA included data from the global, Phase III ADVOCATE trial, which demonstrated statistical superiority in sustaining remission at 52 weeks in the avacopan group compared to the prednisone group.

                            Product Name : Tavneos

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 17, 2020

                            Lead Product(s) : Avacopan,Azathioprine,Rituximab

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Amgen Inc

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                            EPSC
                            Not Confirmed

                            Amgen Inc

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                            EPSC
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                            Lead Product(s) : Avacopan,Azathioprine,Rituximab

                            Therapeutic Area : Immunology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ChemoCentryx Announces Plenary Session at ACR Convergence 2020 to Highlight Data from ADVOCATE Phase III Trial...

                            Details : The study showed that avacopan was as effective as prednisone therapy in bringing patients into remission by 26 weeks, and superior to prednisone for sustained remission after 52 weeks.

                            Product Name : Tavneos

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 11, 2020

                            Lead Product(s) : Avacopan,Azathioprine,Rituximab

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            CSL

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                            EPSC
                            Not Confirmed

                            CSL

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                            Lead Product(s) : Avacopan,Azathioprine,Rituximab

                            Therapeutic Area : Immunology

                            Study Phase : Phase III

                            Sponsor : Amgen Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            VFMCRP and ChemoCentryx Announce European Medicines Agency has Accepted to Review the Marketing Authorization ...

                            Details : If approved, avacopan would be the first orally administered selective complement 5a receptor inhibitor, for the treatment of patients with anti-neutrophil cytoplasmic antibody-associated vasculitis.

                            Product Name : Tavneos

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 11, 2020

                            Lead Product(s) : Avacopan,Azathioprine,Rituximab

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase III

                            Sponsor : Amgen Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Nova Laboratories

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                            EPSC
                            Not Confirmed

                            Nova Laboratories

                            United Kingdom arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Azathioprine

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : Medicines Evaluation Unit | Syne Qua Non Limited | Alderley Analytical | Black County Pathology Services | Diamond Pharma Services | Boyd Consultants

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bioequivalence of Azathioprine Suspension 10 mg/mL (Jayempi) Versus Azathioprine Tablet 50mg (Imurek®)

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            April 29, 2019

                            Lead Product(s) : Azathioprine

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : Medicines Evaluation Unit | Syne Qua Non Limited | Alderley Analytical | Black County Pathology Services | Diamond Pharma Services | Boyd Consultants

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Kyungpook National University Hospital

                            Country arrow
                            EPSC
                            Not Confirmed

                            Kyungpook National University Hospital

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                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Azathioprine

                            Therapeutic Area : Immunology

                            Study Phase : Phase IV

                            Sponsor : Celltrion

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Azathioprine Based on Endoscopy After Clinical Remission in Moderate to Severe Ulcerative Colitis

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 20, 2015

                            Lead Product(s) : Azathioprine

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase IV

                            Sponsor : Celltrion

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives

                            Country arrow
                            EPSC
                            Not Confirmed

                            Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives

                            Country arrow
                            EPSC
                            Not Confirmed
                            • fda
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                            Lead Product(s) : Azathioprine

                            Therapeutic Area : Immunology

                            Study Phase : Phase IV

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Randomized, Multicenter Open Label Study Comparing Early Administration of Azathioprine Plus IFX to Steroids...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            April 24, 2015

                            Lead Product(s) : Azathioprine

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase IV

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            F. Hoffmann-La Roche

                            Switzerland arrow
                            EPSC
                            Not Confirmed

                            F. Hoffmann-La Roche

                            Switzerland arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Azathioprine

                            Therapeutic Area : Immunology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study of Subcutaneous Tocilizumab as Monotherapy and/or in Combination With Non-Biologic Disease Modifying A...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 13, 2013

                            Lead Product(s) : Azathioprine

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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