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    [{"orgOrder":0,"company":"Crinetics Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"Atumelnant","moa":"ACTH||MC2R","graph1":"Undisclosed","graph2":"Phase I","graph3":"Crinetics Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Solution","sponsorNew":"Crinetics Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Crinetics Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Crinetics Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"Atumelnant","moa":"ACTH||MC2R","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Crinetics 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Disease","country":"U.S.A","productType":"Miscellaneous","year":"2021","type":"Inapplicable","leadProduct":"Atumelnant","moa":"MC2R","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Crinetics Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Crinetics Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Crinetics Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Crinetics Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Miscellaneous","year":"2025","type":"Inapplicable","leadProduct":"Atumelnant","moa":"MC2R","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Crinetics Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic 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Disease","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Crinetics Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Crinetics Pharmaceuticals \/ Undisclosed"}]

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                            01

                            Quotient Sciences

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                            Lead Product(s) : Atumelnant

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase I

                            Sponsor : Crinetics Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Quotient Sciences Supports Crinetics Pharmaceuticals with Fully Integrated Pediatric Development and Clinical ...

                            Details : Under the partnership, Quotient will support Crinetics' CRN04894 pediatric program. The partnership will utilize Quotient Sciences' unique Translational Pharmaceutics® platform to provide integrated formulation development, clinical manufacturing, and t...

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            March 30, 2023

                            Lead Product(s) : Atumelnant

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase I

                            Sponsor : Crinetics Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            Quotient

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                            02

                            Crinetics Pharmaceuticals

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                            Crinetics Pharmaceuticals

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                            Lead Product(s) : Atumelnant

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II/ Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)

                            Details : Atumelnant is a Small Molecule drug candidate drug candidate, which is currently being evaluated in Phase II/ Phase III clinical studies for the treatment of Adrenal Hyperplasia, Congenital.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            September 08, 2025

                            Lead Product(s) : Atumelnant

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Crinetics Pharmaceuticals

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                            AIChE Annual Meeting
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                            Crinetics Pharmaceuticals

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                            AIChE Annual Meeting
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                            Lead Product(s) : Atumelnant

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study to Evaluate Atumelnant in Adults with Congenital Adrenal Hyperplasia

                            Details : Atumelnant is a Other Small Molecule drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Adrenal Hyperplasia, Congenital.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            August 27, 2025

                            Lead Product(s) : Atumelnant

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Crinetics Pharmaceuticals

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                            AIChE Annual Meeting
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                            Crinetics Pharmaceuticals

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                            AIChE Annual Meeting
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                            Lead Product(s) : Atumelnant

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Crinetics Announces Phase 2 Data for Atumelnant in Congenital Adrenal Hyperplasia

                            Details : CRN04894 (atumelnant) is an orally active nonpeptide MC2R or adrenocorticotropic hormone (ACTH) antagonist. It is being evaluated for the treatment of congenital adrenal hyperplasia.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            January 10, 2025

                            Lead Product(s) : Atumelnant

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Crinetics Pharmaceuticals

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                            AIChE Annual Meeting
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                            Crinetics Pharmaceuticals

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                            AIChE Annual Meeting
                            Not Confirmed
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                            Lead Product(s) : Atumelnant

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            An Extension Study to Evaluate Safety and Efficacy in Participants Treated With CRN04894

                            Details : Atumelnant is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Adrenal Hyperplasia, Congenital.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            December 02, 2024

                            Lead Product(s) : Atumelnant

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Crinetics Pharmaceuticals

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                            AIChE Annual Meeting
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                            Crinetics Pharmaceuticals

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                            Lead Product(s) : Atumelnant

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Crinetics Presents Advancements from Atumelnant and Paltusotine Programs at ENDO 2024

                            Details : CRN04894 (atumelnant) is an orally active nonpeptide melanocortin 2 receptor (MC2R) or adrenocorticotropic hormone (ACTH) antagonist. It is being evaluated for congenital adrenal hyperplasia.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            May 08, 2024

                            Lead Product(s) : Atumelnant

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Crinetics Pharmaceuticals

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                            Crinetics Pharmaceuticals

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                            AIChE Annual Meeting
                            Not Confirmed
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                            Lead Product(s) : Atumelnant

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Single and Multiple-Ascending Dose Study of CRN04894 in Healthy Volunteers

                            Details : CRN04894 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            September 21, 2023

                            Lead Product(s) : Atumelnant

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Crinetics Pharmaceuticals

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                            AIChE Annual Meeting
                            Not Confirmed

                            Crinetics Pharmaceuticals

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                            AIChE Annual Meeting
                            Not Confirmed
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                            Lead Product(s) : Atumelnant

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Evaluate the Safety, Efficacy, and Pharmacokinetics of CRN04894 in Participants With Congenital Adrenal Hyperp...

                            Details : CRN04894 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Adrenal Hyperplasia, Congenital.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            June 18, 2023

                            Lead Product(s) : Atumelnant

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Crinetics Pharmaceuticals

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                            AIChE Annual Meeting
                            Not Confirmed

                            Crinetics Pharmaceuticals

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                            AIChE Annual Meeting
                            Not Confirmed
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                            Lead Product(s) : Atumelnant

                            Therapeutic Area : Endocrinology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome

                            Details : Atumelnant is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Cushing Syndrome.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            April 07, 2023

                            Lead Product(s) : Atumelnant

                            Therapeutic Area : Endocrinology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Crinetics Pharmaceuticals

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                            AIChE Annual Meeting
                            Not Confirmed

                            Crinetics Pharmaceuticals

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                            AIChE Annual Meeting
                            Not Confirmed
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                            Lead Product(s) : Atumelnant

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Additional Analyses of CRN04894 Preclinical and Phase 1 Results to be Presented at the 10th International Cong...

                            Details : CRN04894, has exhibited strong binding affinity for MC2R in preclinical models and demonstrated suppression of adrenally derived glucocorticoids and androgens that are under the control of ACTH.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            August 04, 2022

                            Lead Product(s) : Atumelnant

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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