[{"orgOrder":0,"company":"Assistance Publique \u2013 H\u00f4pitaux de Paris","sponsor":"Johannes Gutenberg University Mainz | Life Sciences Research Partners | Canadian Institutes of Health Research | Instituto de Salud Carlos III | International Network of VENous Thromboembolism Clinical Research Networks | Boehringer Ingelheim GmbH","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"FRANCE","productType":"Enzyme","year":"2020","type":"Inapplicable","leadProduct":"Alteplase","moa":"Tissue-type plasminogen activator","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III","graph3":"Assistance Publique \u2013 H\u00f4pitaux de Paris","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Assistance Publique \u2013 H\u00f4pitaux de Paris \/ Johannes Gutenberg University Mainz | Life Sciences Research Partners | Canadian Institutes of Health Research | Instituto de Salud Carlos III | International Network of VENous Thromboembolism Clinical Research Networks | Boehringer Ingelheim GmbH","highestDevelopmentStatusID":"10","companyTruncated":"Assistance Publique \u2013 H\u00f4pitaux de Paris \/ Johannes Gutenberg University Mainz | Life Sciences Research Partners | Canadian Institutes of Health Research | Instituto de Salud Carlos III | International Network of VENous Thromboembolism Clinical Research Networks | Boehringer Ingelheim GmbH"},{"orgOrder":0,"company":"Boehringer Ingelheim GmbH","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"GERMANY","productType":"Enzyme","year":"2020","type":"Inapplicable","leadProduct":"Alteplase","moa":"Tissue-type plasminogen activator","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Phase II\/ Phase III","graph3":"Boehringer Ingelheim GmbH","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Boehringer Ingelheim GmbH \/ Undisclosed","highestDevelopmentStatusID":"9","companyTruncated":"Boehringer Ingelheim GmbH \/ Undisclosed"},{"orgOrder":0,"company":"Boehringer Ingelheim GmbH","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"GERMANY","productType":"Enzyme","year":"2021","type":"Inapplicable","leadProduct":"Alteplase","moa":"Tissue-type plasminogen activator","graph1":"Infections and Infectious Diseases","graph2":"Phase II\/ Phase III","graph3":"Boehringer Ingelheim GmbH","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Boehringer Ingelheim GmbH \/ Undisclosed","highestDevelopmentStatusID":"9","companyTruncated":"Boehringer Ingelheim GmbH \/ Undisclosed"},{"orgOrder":0,"company":"Boehringer Ingelheim GmbH","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"GERMANY","productType":"Enzyme","year":"2020","type":"Inapplicable","leadProduct":"Alteplase","moa":"Tissue-type plasminogen activator","graph1":"Undisclosed","graph2":"Phase III","graph3":"Boehringer Ingelheim GmbH","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Boehringer Ingelheim GmbH \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Boehringer Ingelheim GmbH \/ Undisclosed"},{"orgOrder":0,"company":"Generium","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"RUSSIA","productType":"Enzyme","year":"2025","type":"Inapplicable","leadProduct":"Alteplase","moa":"Tissue-type plasminogen activator","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III","graph3":"Generium","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Generium \/ Undisclosed","highestDevelopmentStatusID":"10","companyTruncated":"Generium \/ Undisclosed"},{"orgOrder":0,"company":"Denver Health and Hospital Authority","sponsor":"Genentech | University of Colorado, Denver | National Jewish Health | Beth Israel Deaconess Medical Center | Long Island Jewish Medical Center | Scripps Health | St. Mary's Medical Center | University of Miami | Ben Taub Hospital | The Methodist Hospital ","pharmaFlowCategory":"DU","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"U.S.A","productType":"Enzyme","year":"2020","type":"Inapplicable","leadProduct":"Alteplase","moa":"Tissue-type plasminogen activator","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Phase II","graph3":"Denver Health and Hospital Authority","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Denver Health and Hospital Authority \/ Genentech | University of Colorado, Denver | National Jewish Health | Beth Israel Deaconess Medical Center | Long Island Jewish Medical Center | Scripps Health | St. Mary's Medical Center | University of Miami | Ben Taub Hospital | The Methodist Hospital ","highestDevelopmentStatusID":"8","companyTruncated":"Denver Health and Hospital Authority \/ Genentech | University of Colorado, Denver | National Jewish Health | Beth Israel Deaconess Medical Center | Long Island Jewish Medical Center | Scripps Health | St. Mary's Medical Center | University of Miami | Ben Taub Hospital | The Methodist Hospital "},{"orgOrder":0,"company":"University of Colorado Denver","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Enzyme","year":"2020","type":"Inapplicable","leadProduct":"Alteplase","moa":"Tissue-type plasminogen activator","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"University of Colorado Denver","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Infusion","sponsorNew":"University of Colorado Denver \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"University of Colorado Denver \/ Undisclosed"},{"orgOrder":0,"company":"Memorial Healthcare System","sponsor":"Genentech","pharmaFlowCategory":"DU","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"U.S.A","productType":"Enzyme","year":"2021","type":"Inapplicable","leadProduct":"Alteplase","moa":"Tissue-type plasminogen activator","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Phase IV","graph3":"Memorial Healthcare System","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Memorial Healthcare System \/ Genentech","highestDevelopmentStatusID":"11","companyTruncated":"Memorial Healthcare System \/ Genentech"},{"orgOrder":0,"company":"South West Sydney Local Health District","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"AUSTRALIA","productType":"Enzyme","year":"2022","type":"Inapplicable","leadProduct":"Alteplase","moa":"Tissue-type plasminogen activator","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Phase II","graph3":"South West Sydney Local Health District","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"South West Sydney Local Health District \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"South West Sydney Local Health District \/ Undisclosed"},{"orgOrder":0,"company":"Ji Xunming","sponsor":"Beijing Friendship Hospital | Beijing Shijitan Hospital, Capital Medical University | Beijing Tongren Hospital | People\u2019s Hospital of Beijing Daxing District | Tianjin Huanhu Hospital | Guizhou Provincial People's Hospital | Shandong Provincial Hospital |","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"","productType":"Enzyme","year":"2023","type":"Inapplicable","leadProduct":"Alteplase","moa":"Tissue-type plasminogen activator","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase III","graph3":"Ji Xunming","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Ji Xunming \/ Beijing Friendship Hospital | Beijing Shijitan Hospital, Capital Medical University | Beijing 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IV","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hamilton Health Sciences \/ Undisclosed","highestDevelopmentStatusID":"11","companyTruncated":"Hamilton Health Sciences \/ Undisclosed"}]

Find Clinical Drug Pipeline Developments & Deals for Alteplase

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                          Top Deals by Deal Size (USD bn)

                          01

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : Alteplase is a Enzyme drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Myocardial Infarction.

                          Product Name : Undisclosed

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          August 28, 2025

                          Lead Product(s) : Alteplase

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Ji Xunming

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Ji Xunming

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Lead Product(s) : Alteplase

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Study Phase : Phase III

                          Sponsor : Beijing Friendship Hospital | Beijing Shijitan Hospital, Capital Medical University | Beijing Tongren Hospital | People’s Hospital of Beijing Daxing District | Tianjin Huanhu Hospital | Guizhou Provincial People's Hospital | Shandong Provincial Hospital |

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Alteplase is a Enzyme drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Ischemic Stroke.

                          Product Name : Undisclosed

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          July 28, 2023

                          Lead Product(s) : Alteplase

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase III

                          Sponsor : Beijing Friendship Hospital | Beijing Shijitan Hospital, Capital Medical University | Beijing Tongren Hospital | People’s Hospital of Beijing Daxing District | Tianjin Huanhu Hospital | Guizhou Provincial People's Hospital | Shandong Provincial Hospital |

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          South West Sydney Local Health District

                          Country arrow
                          BioJapan
                          Not Confirmed

                          South West Sydney Local Health District

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Details : Alteplase is a Enzyme drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Respiratory Insufficiency.

                          Product Name : Undisclosed

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          September 15, 2022

                          Lead Product(s) : Alteplase

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : Tissue Plasminogen Activator is a Protein drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Hematoma, Subdural.

                          Product Name : Undisclosed

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          August 08, 2022

                          Lead Product(s) : Alteplase

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase IV

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : It evaluated efficacy and safety of two different dosing regimens of intravenous alteplase given for up to 5 days on top of best available medical management (standard of care (SOC)), compared with SOC alone.

                          Product Name : Undisclosed

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          July 26, 2021

                          Lead Product(s) : Alteplase

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Memorial Healthcare System

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Memorial Healthcare System

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Details : Alteplase is a Enzyme drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Pleural Effusion.

                          Product Name : Undisclosed

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          March 19, 2021

                          Lead Product(s) : Alteplase

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : Phase IV

                          Sponsor : Genentech

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : Alteplase is a Enzyme drug candidate, which is currently being evaluated in phase II/ phase III clinical studies for the treatment of Respiratory Distress Syndrome.

                          Product Name : Undisclosed

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          November 23, 2020

                          Lead Product(s) : Alteplase

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          08

                          Assistance Publique – Hôpitaux de Paris

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Assistance Publique – Hôpitaux de Paris

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Lead Product(s) : Alteplase

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Study Phase : Phase III

                          Sponsor : Johannes Gutenberg University Mainz | Life Sciences Research Partners | Canadian Institutes of Health Research | Instituto de Salud Carlos III | International Network of VENous Thromboembolism Clinical Research Networks | Boehringer Ingelheim GmbH

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Alteplase is a Enzyme drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Pulmonary Embolism.

                          Product Name : Undisclosed

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          June 12, 2020

                          Lead Product(s) : Alteplase

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase III

                          Sponsor : Johannes Gutenberg University Mainz | Life Sciences Research Partners | Canadian Institutes of Health Research | Instituto de Salud Carlos III | International Network of VENous Thromboembolism Clinical Research Networks | Boehringer Ingelheim GmbH

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : Alteplase is a Enzyme drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.

                          Product Name : Undisclosed

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          June 05, 2020

                          Lead Product(s) : Alteplase

                          Therapeutic Area : Undisclosed

                          Highest Development Status : Phase I

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Denver Health and Hospital Authority

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Denver Health and Hospital Authority

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Lead Product(s) : Alteplase

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Study Phase : Phase II

                          Sponsor : Genentech | University of Colorado, Denver | National Jewish Health | Beth Israel Deaconess Medical Center | Long Island Jewish Medical Center | Scripps Health | St. Mary's Medical Center | University of Miami | Ben Taub Hospital | The Methodist Hospital

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Alteplase is a Enzyme drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Severe Acute Respiratory Syndrome.

                          Product Name : Undisclosed

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          April 22, 2020

                          Lead Product(s) : Alteplase

                          Therapeutic Area : Pulmonary/Respiratory Diseases

                          Highest Development Status : Phase II

                          Sponsor : Genentech | University of Colorado, Denver | National Jewish Health | Beth Israel Deaconess Medical Center | Long Island Jewish Medical Center | Scripps Health | St. Mary's Medical Center | University of Miami | Ben Taub Hospital | The Methodist Hospital

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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