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Find Clinical Drug Pipeline Developments & Deals by Almirall
Almirall obtains exclusive global rights to develop and commercialize ZKN-013, Eloxx’s lead TURBO-ZM based molecule, for the treatment of rare dermatological and other diseases associated with nonsense mutations.
Through a license agreement, Almirall gets access of anti-IL-21 monoclonal antibody NN-8828, which it plans to develop for the treatment of immune inflammatory dermatological diseases.
ALM223 (IL-2 mu-Fc) is a modified version of the protein IL-2 designed to selectively activate Regulatory T cells (Tregs). It is being evaluated in Phase I clinical studies for the patients related to Autoinmune dermatology.
The collaboration aims to discover and develop new mRNA-based therapies for severe skin diseases, including non-melanoma skin cancer by leveraging etherna’s innovative mRNA/LNP technology platform and LNP formulations with Almirall’s leading expertise in dermatology.
Ebglyss (lebrikizumab) is a monoclonal antibody that binds IL-13 with high affinity to specifically prevent the formation of the IL-13Rα1/IL-4Rα heterodimer complex. It is approved for the treatment of moderate-to-severe atopic dermatitis.
The partnership combines Absci’s de novo AI Drug Creation™ platform with Almirall’s dermatological expertise with the goal of delivering life-changing medicines to patients, marking another step forward in AI drug creation.
Under the terms of this agreement, Almirall will gain a license to utilize EpimAb’s proprietary Fabs-In-Tandem Immunoglobulin (FIT-Ig®) platform technology to generate, develop and commercialize bispecific antibodies, for which Almirall will have exclusive global rights.
Ebglyss (lebrikizumab) is an investigational, monoclonal antibody that binds IL-13, which is received positive CHMP opinion for moderate-to-severe atopic dermatitis.
Through the acquisition, Almirall get exclusive rights to commercialize the Prometax (rivastigmine hydrogen tartrate), a multi-day transdermal patch for the treatment of Alzheimer’s disease.
Ilumetri (tildrakizumab) is a humanized mAb that targets the p19 subunit of IL-23 and inhibits the release of proinflammatory cytokines and chemokines with limited impact on the rest of the immune system. It is indicated for adults with moderate-to-severe plaque psoriasis.
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