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[{"orgOrder":0,"company":"Aiolos Bio","sponsor":"Atlas Venture","pharmaFlowCategory":"D","amount":"$245.0 million","upfrontCash":"Undisclosed","newsHeadline":"Aiolos Bio Launches with $245 Million Series A Investment to Advance Development of Novel, Phase 2-Ready TSLP Antibody","therapeuticArea":"Pulmonary\/Respiratory Diseases","highestDevelopmentStatus":"Phase II","country":"U.S.A","productType":"Large molecule","productStatus":"New Molecular Entity","date":"October 2023","url1":"","url2":"","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Phase II"},{"orgOrder":0,"company":"Aiolos Bio","sponsor":"GSK","pharmaFlowCategory":"D","amount":"$1,400.0 million","upfrontCash":"$1,000.0 million","newsHeadline":"GSK Enters Agreement to Acquire Aiolos Bio","therapeuticArea":"Pulmonary\/Respiratory Diseases","highestDevelopmentStatus":"Phase I","country":"U.S.A","productType":"Large molecule","productStatus":"New Molecular Entity","date":"January 2024","url1":"","url2":"","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Phase I"},{"orgOrder":0,"company":"Aiolos Bio","sponsor":"GSK","pharmaFlowCategory":"D","amount":"$1,400.0 million","upfrontCash":"$1,000.0 million","newsHeadline":"GSK Completes Acquisition of Aiolos Bio for Up to $1.4 Bln","therapeuticArea":"Pulmonary\/Respiratory Diseases","highestDevelopmentStatus":"Phase I","country":"U.S.A","productType":"Large molecule","productStatus":"New Molecular Entity","date":"February 2024","url1":"","url2":"","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Phase I"}]

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            Details:

            The acquisition of Aiolos includes AIO-001, a potentially best-in-class, long-acting anti-thymic stromal lymphopoietin monoclonal antibody, which is being evaluated in the treatment of asthma, chronic rhinosinusitis with nasal polyps, nasal polyps.

            Lead Product(s): AIO-001

            Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: AIO-001

            Highest Development Status: Phase I Product Type: Large molecule

            Partner/Sponsor/Collaborator: GSK

            Deal Size: $1,400.0 million Upfront Cash: $1,000.0 million

            Deal Type: Acquisition February 15, 2024

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            Details:

            The acquisition expands GSK’s respiratory pipeline adding AIO-001, a phase II-ready, long-acting anti-thymic stromal lymphopoietin monoclonal antibody for adult patients with asthma, with potential for additional indications including chronic rhinosinusitis with nasal polyps.

            Lead Product(s): AIO-001

            Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: AIO-001

            Highest Development Status: Phase I Product Type: Large molecule

            Partner/Sponsor/Collaborator: GSK

            Deal Size: $1,400.0 million Upfront Cash: $1,000.0 million

            Deal Type: Acquisition January 09, 2024

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            Details:

            The net proceeds will be used to advance company's lead drug candidate, AIO-001, an anti-thymic stromal lymphopoietin (TSLP) monoclonal antibody, into a Phase 2 clinical trial in moderate-to-severe asthma patients.

            Lead Product(s): AIO-001

            Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: AIO-001

            Highest Development Status: Phase II Product Type: Large molecule

            Partner/Sponsor/Collaborator: Atlas Venture

            Deal Size: $245.0 million Upfront Cash: Undisclosed

            Deal Type: Series A Financing October 24, 2023

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