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Details:
The acquisition of Aiolos includes AIO-001, a potentially best-in-class, long-acting anti-thymic stromal lymphopoietin monoclonal antibody, which is being evaluated in the treatment of asthma, chronic rhinosinusitis with nasal polyps, nasal polyps.
Lead Product(s): AIO-001
Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: AIO-001
Highest Development Status: Phase I Product Type: Large molecule
Partner/Sponsor/Collaborator: GSK
Deal Size: $1,400.0 million Upfront Cash: $1,000.0 million
Deal Type: Acquisition February 15, 2024
Details:
The acquisition expands GSK’s respiratory pipeline adding AIO-001, a phase II-ready, long-acting anti-thymic stromal lymphopoietin monoclonal antibody for adult patients with asthma, with potential for additional indications including chronic rhinosinusitis with nasal polyps.
Lead Product(s): AIO-001
Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: AIO-001
Highest Development Status: Phase I Product Type: Large molecule
Partner/Sponsor/Collaborator: GSK
Deal Size: $1,400.0 million Upfront Cash: $1,000.0 million
Deal Type: Acquisition January 09, 2024
Details:
The net proceeds will be used to advance company's lead drug candidate, AIO-001, an anti-thymic stromal lymphopoietin (TSLP) monoclonal antibody, into a Phase 2 clinical trial in moderate-to-severe asthma patients.
Lead Product(s): AIO-001
Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: AIO-001
Highest Development Status: Phase II Product Type: Large molecule
Partner/Sponsor/Collaborator: Atlas Venture
Deal Size: $245.0 million Upfront Cash: Undisclosed
Deal Type: Series A Financing October 24, 2023