Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : ADX-626
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Phase 1 Study of ADX-626 in Healthy Participants
Details : ADX-626 is a Oligonucleotide drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of unspecified medical condition.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
July 23, 2025
Lead Product(s) : ADX-626
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ADX-038
Therapeutic Area : Nephrology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Phase 2 Study of ADX-038 in Complement-Mediated Kidney Disease
Details : ADX-038 is a drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Glomerulonephritis, IGA.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
May 25, 2025
Lead Product(s) : ADX-038
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ADX-038
Therapeutic Area : Ophthalmology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Phase 2 Study of ADX-038 in Participants with Geographic Atrophy
Details : ADX-038 is a drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Wet Macular Degeneration.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
May 25, 2025
Lead Product(s) : ADX-038
Therapeutic Area : Ophthalmology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Study Phase : Discovery
Sponsor : AbbVie Inc
Deal Size : Undisclosed
Deal Type : Collaboration
AbbVie Dives Further Into siRNA With $335M Upfront in ADARx Deal
Details : The collaboration will leverage ADARx's RNA discovery expertise and proprietary siRNA technology to develop siRNA therapeutics across multiple disease areas, including immunology and oncology.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : $335.0 million
May 14, 2025
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Highest Development Status : Discovery
Sponsor : AbbVie Inc
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : ADX-324
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
STOP-HAE: A Phase 3 Study of ADX-324 in HAE
Details : ADX-324 is a Oligonucleotide drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Angioedemas, Hereditary.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
May 07, 2025
Lead Product(s) : ADX-324
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ADX-850
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase I
Sponsor : ADARx Pharmaceuticals | Avance Clinical
Deal Size : Inapplicable
Deal Type : Inapplicable
Safety, Tolerability, PK and PD of ADX-850 in Participants With Hypertension
Details : ADX-850 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Hypertension.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
January 16, 2024
Lead Product(s) : ADX-850
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase I
Sponsor : ADARx Pharmaceuticals | Avance Clinical
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ADX-324
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Bain Capital Life Sciences
Deal Size : $200.0 million
Deal Type : Series C Financing
Details : The net proceeds will advance ADARx clinical programs including ADX-324, a siRNA designed to reduce the production of PKK, a protein critical to the etiology of hereditary angioedema, and ADX-038, under development for the treatment of paroxysmal nocturn...
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Undisclosed
August 09, 2023
Lead Product(s) : ADX-324
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Bain Capital Life Sciences
Deal Size : $200.0 million
Deal Type : Series C Financing
Lead Product(s) : ADX-038
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I/ Phase II
Sponsor : ADARx Pharmaceuticals | Novotech
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ADX-038 is a drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Hemoglobinuria, Paroxysmal.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
May 25, 2023
Lead Product(s) : ADX-038
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I/ Phase II
Sponsor : ADARx Pharmaceuticals | Novotech
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ADX-324
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Avance Clinical
Deal Size : Inapplicable
Deal Type : Inapplicable
Safety, Tolerability, PK, PD of ADX-324 in Healthy Volunteers and Hereditary Angioedema Patients
Details : ADX-324 is a Oligonucleotide drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Angioedemas, Hereditary.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
January 20, 2023
Lead Product(s) : ADX-324
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Avance Clinical
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ADX-324
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Ascenta Capital
Deal Size : $46.0 million
Deal Type : Series B Financing
ADARx Pharmaceuticals Raises $46 Million as Lead Product Enters the Clinic
Details : The net proceeds will be used to advance ADARx’s proprietary RNA targeting platform together with novel oligonucleotide delivery technologies and to initiate phase I clinical trial of ADX-324 (siRNA duplex oligonucleotide), for the treatment of heredit...
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Undisclosed
January 20, 2023
Lead Product(s) : ADX-324
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Ascenta Capital
Deal Size : $46.0 million
Deal Type : Series B Financing