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Find Clinical Drug Pipeline Developments & Deals by Abivax
The proceeds are expected to be allocated mainly to the development of ABX464 (obefazimod), an oral, first-in-class, small molecule, for the treatment of adults with moderately to severely active UC and other potential chronic inflammatory indications.
ABX464 (Obefazimod), is a highly differentiated oral drug candidate, with a novel mechanism of action based on the upregulation of a single microRNA (miR-124) with potent anti-inflammatory properties.
The Company plans to use the net proceeds for the launch and continuation of the clinical programs of ABX464 (obefazimod), the Company's lead drug candidate in clinical development for ulcerative colitis.
ABX464 (Obefazimod), is a highly differentiated oral drug candidate, with a novel mechanism of action based on the upregulation of a single microRNA (miR-124) with potent anti-inflammatory properties.
ABX464 (Obefazimod), is a highly differentiated oral drug candidate, with a novel mechanism of action based on the upregulation of a single microRNA (miR-124) with potent anti-inflammatory properties.
The ABTECT program aims to confirm obefazimod’s potential to maintain and further improve patient-outcomes over time, as well as its safety and tolerability profile, as already observed during previously conducted Phase 2a and Phase 2b clinical trials in moderate to severe UC.
In consultation with international regulators, including both FDA and EMA, obefazimod 25mg and 50mg will be investigated in ABTECT program for treatment of UC in advanced therapies (AT) naive and in AT-failure patients to support future submission of marketing authorizations.
ABX464 (obefazimod) is a small molecule that selectively upregulates miR-124 in immune cells. We aimed to assess ABX464 as a treatment for patients with moderate-to-severe, active ulcerative colitis.
The planned use of the net proceeds of the Transaction is, based on the Company’s current plans, follows the launch and continuation of the clinical programs of obefazimod (ABX464), the Company’s lead product in advanced development.
ABX464 (obefazimod) is an oral, first-in-class, small molecule that has demonstrated safety and profound anti-inflammatory activity in preclinical trials and in Phase 2a and Phase 2b induction trials to treat ulcerative colitis (UC).
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