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22-25 February, 2026
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23-25 February, 2026
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24-25 February, 2026
Digital content

15 Jan 2026
// FIERCE BIOTECH
https://www.fiercebiotech.com/biotech/italys-alfasigma-pens-eu125m-deal-injectable-form-german-biotechs-hsv-treatment

13 Jan 2026
// PHARMIWEB
https://www.pharmiweb.com/press-release/2026-01-13/alfasigma-secures-exclusive-rights-from-innovative-molecules-to-parenteral-adibelivir-for-treatment-of-hsv-encephalitis-an-ultra-rare-disease

11 Sep 2025
// GLOBENEWSWIRE
https://www.globenewswire.com/news-release/2025/09/11/3148535/23024/en/Intercept-Announces-Voluntary-Withdrawal-of-OCALIVA-for-Primary-Biliary-Cholangitis-PBC-from-the-US-Market-US-Clinical-Trials-Involving-Obeticholic-Acid-Placed-on-Clinical-Hold.html

30 Jul 2025
// FIERCE PHARMA
https://www.fiercepharma.com/pharma/alfasigma-touts-results-phase-3-trial-former-galapagos-jak-inhibitor-jyseleca

28 Jul 2025
// BUSINESSWIRE
https://www.businesswire.com/news/home/20250728902063/en/Filgotinib-Shows-Positive-Topline-Results-Across-Full-Spectrum-of-Axial-Spondyloarthritis-in-OLINGUITO-Phase-3-Study

19 Nov 2024
// PR NEWSWIRE
https://www.prnewswire.com/news-releases/forging-new-paths-alfasigma-group-and-fangzhou-inc-chart-a-course-for-internet-healthcare-302310791.html
USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others
GDUFA
DMF Review : N/A
Rev. Date :
Pay. Date :
DMF Number : 482
Submission : 1962-04-26
Status : Inactive
Type : II

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others
GDUFA
DMF Review : N/A
Rev. Date :
Pay. Date :
DMF Number : 8436
Submission : 1990-02-19
Status : Inactive
Type : II

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others
GDUFA
DMF Review : N/A
Rev. Date :
Pay. Date :
DMF Number : 466
Submission : 1962-02-15
Status : Inactive
Type : II

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others
Registrant Name : Aju Pharmaceutical Co., Ltd.
Registration Date : 2013-01-31
Registration Number : 20121026-149-I-108-01(1)
Manufacturer Name : Alfasigma SpA@ OPOCRIN SpA
Manufacturer Address : Via ENRICO FERMI 1-65020 ALANNO(PE), ITALY@Via Pacinotti, 3 41043 CORLO Di FORMIGINE (Modena), Italy

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others
Registrant Name : Samoh Pharmaceutical Co., Ltd.
Registration Date : 2012-10-26
Registration Number : 20121026-149-I-108-01
Manufacturer Name : Alfasigma SpA/@OPOCRIN SpA_x000D_ @Samoh Pharmaceutical Co., Ltd.
Manufacturer Address : Via Enrico Fermi 1-65020 Alanno (PE), Italy@Via Pacinotti, 3 41043 CORLO Di FORMIGINE (Modena), Italy_x000D_ @(135-925)7th floor, Samoh Building, 151 Yeoksam-ro, Gangnam-gu, Seoul _x000D_

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Details:
Through the licensing deal for Adibelivir, the agreement aims to advance HSV encephalitis treatment by targeting the HSV helicase-primase complex.
Lead Product(s): Adibelivir
Therapeutic Area: Infections and Infectious Diseases Brand Name: Undisclosed
Study Phase: IND EnablingProduct Type: Miscellaneous
Recipient: Innovative Molecules
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Licensing Agreement January 14, 2026

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Lead Product(s) : Adibelivir
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : IND Enabling
Recipient : Innovative Molecules
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Alfasigma Secures Exclusive Rights for Parenteral Adibelivir in HSV Encephalitis
Details : Through the licensing deal for Adibelivir, the agreement aims to advance HSV encephalitis treatment by targeting the HSV helicase-primase complex.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
January 14, 2026

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Details:
Through the licensing deal for Adibelivir, the agreement aims to advance HSV encephalitis treatment by targeting the HSV helicase-primase complex.
Lead Product(s): Adibelivir
Therapeutic Area: Infections and Infectious Diseases Brand Name: IM 250
Study Phase: Phase IProduct Type: Miscellaneous
Recipient: Innovative Molecules
Deal Size: $145.6 million Upfront Cash: Undisclosed
Deal Type: Licensing Agreement January 13, 2026

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Lead Product(s) : Adibelivir
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Recipient : Innovative Molecules
Deal Size : $145.6 million
Deal Type : Licensing Agreement
Alfasigma Secures Exclusive Rights for Parenteral Adibelivir in HSV Encephalitis
Details : Through the licensing deal for Adibelivir, the agreement aims to advance HSV encephalitis treatment by targeting the HSV helicase-primase complex.
Product Name : IM 250
Product Type : Miscellaneous
Upfront Cash : Undisclosed
January 13, 2026

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Filgotinib is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Colitis, Ulcerative.
Lead Product(s): Filgotinib
Therapeutic Area: Immunology Brand Name: Undisclosed
Study Phase: Phase IIIProduct Type: Miscellaneous
Sponsor: Undisclosed
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable March 07, 2025

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Lead Product(s) : Filgotinib
Therapeutic Area : Immunology
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Study Evaluating the Effects of Filgotinib in Children and Teenagers With Ulcerative Colitis
Details : Filgotinib is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Colitis, Ulcerative.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 07, 2025

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Filgotinib is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Behcet Syndrome.
Lead Product(s): Filgotinib
Therapeutic Area: Rare Diseases and Disorders Brand Name: Undisclosed
Study Phase: Phase IIProduct Type: Miscellaneous
Sponsor: UMC Utrecht
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable February 29, 2024

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Lead Product(s) : Filgotinib
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase II
Partner/Sponsor/Collaborator : UMC Utrecht
Deal Size : Inapplicable
Deal Type : Inapplicable
Drug Rediscovery for Rare Immune Mediated Inflammatory Diseases
Details : Filgotinib is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Behcet Syndrome.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 29, 2024

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Alfasigma completed acquisition of Jyseleca (filgotinib), which provides European and UK Marketing Authorizations. It is used for the treatment of moderate to severe rheumatoid arthritis.
Lead Product(s): Filgotinib
Therapeutic Area: Immunology Brand Name: Jyseleca
Study Phase: Approved FDFProduct Type: Miscellaneous
Recipient: Galapagos
Deal Size: $184.9 million Upfront Cash: $54.3 million
Deal Type: Acquisition January 31, 2024

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Lead Product(s) : Filgotinib
Therapeutic Area : Immunology
Highest Development Status : Approved FDF
Recipient : Galapagos
Deal Size : $184.9 million
Deal Type : Acquisition
Galapagos Completes Transaction to Transfer Jyseleca® Business to Alfasigma
Details : Alfasigma completed acquisition of Jyseleca (filgotinib), which provides European and UK Marketing Authorizations. It is used for the treatment of moderate to severe rheumatoid arthritis.
Product Name : Jyseleca
Product Type : Miscellaneous
Upfront Cash : $54.3 million
January 31, 2024

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Filgotinib is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Arthritis, Juvenile.
Lead Product(s): Filgotinib
Therapeutic Area: Immunology Brand Name: Undisclosed
Study Phase: Phase IProduct Type: Miscellaneous
Sponsor: Undisclosed
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable January 24, 2024

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Lead Product(s) : Filgotinib
Therapeutic Area : Immunology
Highest Development Status : Phase I
Partner/Sponsor/Collaborator : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Filgotinib is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Arthritis, Juvenile.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 24, 2024

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Galapagos transfers Jyseleca (filgotinib) to Alfasigma as part of its transformation into a biotech company focused on immunology and oncology, marking a significant milestone for the company.
Lead Product(s): Filgotinib
Therapeutic Area: Immunology Brand Name: Jyseleca
Study Phase: Approved FDFProduct Type: Miscellaneous
Recipient: Galapagos
Deal Size: $229.7 million Upfront Cash: $54.7 million
Deal Type: Agreement January 02, 2024

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Lead Product(s) : Filgotinib
Therapeutic Area : Immunology
Highest Development Status : Approved FDF
Recipient : Galapagos
Deal Size : $229.7 million
Deal Type : Agreement
Galapagos Signs Agreement to Transfer Jyseleca® Business to Alfasigma
Details : Galapagos transfers Jyseleca (filgotinib) to Alfasigma as part of its transformation into a biotech company focused on immunology and oncology, marking a significant milestone for the company.
Product Name : Jyseleca
Product Type : Miscellaneous
Upfront Cash : $54.7 million
January 02, 2024

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Through the acquisition, Alfasigma adds Ocaliva (obeticholic acid), a farnesoid X receptor agonist approved in the United States for the treatment of primary biliary cholangitis in combination with ursodeoxycholic acid in adults with an inadequate response to UDCA.
Lead Product(s): Obeticholic Acid
Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Brand Name: Ocaliva
Study Phase: Approved FDFProduct Type: Miscellaneous
Recipient: Intercept Pharmaceuticals
Deal Size: $794.0 million Upfront Cash: $794.0 million
Deal Type: Acquisition November 08, 2023

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Lead Product(s) : Obeticholic Acid
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Approved FDF
Recipient : Intercept Pharmaceuticals
Deal Size : $794.0 million
Deal Type : Acquisition
Alfasigma Completes Acquisition of Intercept Pharmaceuticals, Inc.
Details : Through the acquisition, Alfasigma adds Ocaliva (obeticholic acid), a farnesoid X receptor agonist approved in the United States for the treatment of primary biliary cholangitis in combination with ursodeoxycholic acid in adults with an inadequate respon...
Product Name : Ocaliva
Product Type : Miscellaneous
Upfront Cash : $794.0 million
November 08, 2023

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Details:
Through the acquisition, Alfasigma adds Ocaliva (obeticholic acid), a farnesoid X receptor agonist approved in the United States for the treatment of primary biliary cholangitis in combination with ursodeoxycholic acid in adults with an inadequate response to UDCA.
Lead Product(s): Obeticholic Acid,Ursodeoxycholic Acid
Therapeutic Area: Hepatology (Liver, Pancreatic, Gall Bladder) Brand Name: Ocaliva
Study Phase: Approved FDFProduct Type: Miscellaneous
Recipient: Intercept Pharmaceuticals
Deal Size: $794.0 million Upfront Cash: $794.0 million
Deal Type: Acquisition September 26, 2023

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Lead Product(s) : Obeticholic Acid,Ursodeoxycholic Acid
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Approved FDF
Recipient : Intercept Pharmaceuticals
Deal Size : $794.0 million
Deal Type : Acquisition
Details : Through the acquisition, Alfasigma adds Ocaliva (obeticholic acid), a farnesoid X receptor agonist approved in the United States for the treatment of primary biliary cholangitis in combination with ursodeoxycholic acid in adults with an inadequate respon...
Product Name : Ocaliva
Product Type : Miscellaneous
Upfront Cash : $794.0 million
September 26, 2023

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Details:
Filgotinib is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Axial Spondyloarthritis.
Lead Product(s): Filgotinib
Therapeutic Area: Immunology Brand Name: Undisclosed
Study Phase: Phase IIIProduct Type: Miscellaneous
Sponsor: Undisclosed
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable March 27, 2023

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Lead Product(s) : Filgotinib
Therapeutic Area : Immunology
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Study Evaluating the Effect of Filgotinib in Participants With Active Axial Spondyloarthritis
Details : Filgotinib is a Other Small Molecule drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Axial Spondyloarthritis.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
March 27, 2023

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Regulatory Info : Approved
Registration Country : Sweden
Dosage Form : Film Coated Tablet
Brand Name : Jyseleca
Dosage Strength : 100mg
Packaging :
Approval Date : 24-09-2020
Application Number : 2.02E+13
Regulatory Info : Approved
Registration Country : Sweden

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Regulatory Info : Approved
Registration Country : Sweden
Dosage Form : Film Coated Tablet
Brand Name : Jyseleca
Dosage Strength : 200mg
Packaging :
Approval Date : 24-09-2020
Application Number : 2.02E+13
Regulatory Info : Approved
Registration Country : Sweden

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Regulatory Info :
Registration Country : Italy
Dosage Form : Tablets
Brand Name : CYCLOVIRAN
Dosage Strength : 800 mg
Packaging : 35 UNITS 800 MG - ORAL USE
Approval Date :
Application Number :
Regulatory Info :
Registration Country : Italy

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Regulatory Info :
Registration Country : Italy
Dosage Form : Tablets
Brand Name : AMIODAR
Dosage Strength : 200 mg
Packaging : 20 UNITS 200 MG - ORAL USE
Approval Date :
Application Number :
Regulatory Info :
Registration Country : Italy

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Regulatory Info : Prescription
Registration Country : Denmark
Artenimol; Piperaquine Phosphate
Dosage Form : Film Coated Tablet
Brand Name : Eurartesim
Dosage Strength : 20mg; 160mg
Packaging :
Approval Date : 01-07-2011
Application Number : 28104558909
Regulatory Info : Prescription
Registration Country : Denmark

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Regulatory Info : Prescription
Registration Country : Denmark
Artenimol; Piperaquine Phosphate
Dosage Form : Film Coated Tablet
Brand Name : Eurartesim
Dosage Strength : 40mg; 320mg
Packaging :
Approval Date : 01-07-2011
Application Number : 28104559009
Regulatory Info : Prescription
Registration Country : Denmark

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Regulatory Info : Prescription
Registration Country : Estonia
Artenimol; Piperaquine tetraphosphate
Dosage Form : Film-Coated Tablet
Brand Name : Eurartesim
Dosage Strength : 20mg; 160mg
Packaging :
Approval Date :
Application Number :
Regulatory Info : Prescription
Registration Country : Estonia

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Regulatory Info : Prescription
Registration Country : Estonia
Artenimol; Piperaquine tetraphosphate
Dosage Form : Film-Coated Tablet
Brand Name : Eurartesim
Dosage Strength : 40mg; 320mg
Packaging :
Approval Date :
Application Number :
Regulatory Info : Prescription
Registration Country : Estonia

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Regulatory Info : Approved
Registration Country : Sweden
Artenimol; Piperaquine Tetraphosphate
Dosage Form : Film Coated Tablet
Brand Name : Eurartesim
Dosage Strength : 320mg;40mg
Packaging :
Approval Date : 27-10-2011
Application Number : 2.01E+13
Regulatory Info : Approved
Registration Country : Sweden

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Regulatory Info : Approved
Registration Country : Sweden
Artenimol; Piperaquine Tetraphosphate
Dosage Form : Film Coated Tablet
Brand Name : Eurartesim
Dosage Strength : 160mg;20mg
Packaging :
Approval Date : 27-10-2011
Application Number : 2.01E+13
Regulatory Info : Approved
Registration Country : Sweden

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Regulatory Info : Approved
Registration Country : Sweden
Dosage Form : Film Coated Tablet
Dosage Strength : 100mg
Packaging :
Brand Name : Jyseleca
Approval Date : 24-09-2020
Application Number : 2.02E+13
Regulatory Info : Approved
Registration Country : Sweden

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Regulatory Info : Approved
Registration Country : Sweden
Dosage Form : Film Coated Tablet
Dosage Strength : 200mg
Packaging :
Brand Name : Jyseleca
Approval Date : 24-09-2020
Application Number : 2.02E+13
Regulatory Info : Approved
Registration Country : Sweden

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Regulatory Info :
Registration Country : Italy
Dosage Form : Tablets
Dosage Strength : 800 mg
Packaging : 35 UNITS 800 MG - ...
Brand Name : CYCLOVIRAN
Approval Date :
Application Number :
Regulatory Info :
Registration Country : Italy

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Regulatory Info :
Registration Country : Italy
Dosage Form : Tablets
Dosage Strength : 200 mg
Packaging : 20 UNITS 200 MG - ...
Brand Name : AMIODAR
Approval Date :
Application Number :
Regulatory Info :
Registration Country : Italy

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Regulatory Info : Prescription
Registration Country : Denmark
Artenimol; Piperaquine Phosphate
Dosage Form : Film Coated Tablet
Dosage Strength : 20mg; 160mg
Packaging :
Brand Name : Eurartesim
Approval Date : 01-07-2011
Application Number : 28104558909
Regulatory Info : Prescription
Registration Country : Denmark

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Regulatory Info : Prescription
Registration Country : Denmark
Artenimol; Piperaquine Phosphate
Dosage Form : Film Coated Tablet
Dosage Strength : 40mg; 320mg
Packaging :
Brand Name : Eurartesim
Approval Date : 01-07-2011
Application Number : 28104559009
Regulatory Info : Prescription
Registration Country : Denmark

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Regulatory Info : Prescription
Registration Country : Estonia
Artenimol; Piperaquine tetraphosphate
Dosage Form : Film-Coated Tablet
Dosage Strength : 20mg; 160mg
Packaging :
Brand Name : Eurartesim
Approval Date :
Application Number :
Regulatory Info : Prescription
Registration Country : Estonia

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Regulatory Info : Prescription
Registration Country : Estonia
Artenimol; Piperaquine tetraphosphate
Dosage Form : Film-Coated Tablet
Dosage Strength : 40mg; 320mg
Packaging :
Brand Name : Eurartesim
Approval Date :
Application Number :
Regulatory Info : Prescription
Registration Country : Estonia

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Regulatory Info : Approved
Registration Country : Sweden
Artenimol; Piperaquine Tetraphosphate
Dosage Form : Film Coated Tablet
Dosage Strength : 320mg;40mg
Packaging :
Brand Name : Eurartesim
Approval Date : 27-10-2011
Application Number : 2.01E+13
Regulatory Info : Approved
Registration Country : Sweden

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Regulatory Info : Approved
Registration Country : Sweden
Artenimol; Piperaquine Tetraphosphate
Dosage Form : Film Coated Tablet
Dosage Strength : 160mg;20mg
Packaging :
Brand Name : Eurartesim
Approval Date : 27-10-2011
Application Number : 2.01E+13
Regulatory Info : Approved
Registration Country : Sweden

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Alfasigma is a supplier offers 4 products (APIs, Excipients or Intermediates).
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