We are developing first-in-class small molecule therapeutics that treat the underlying pathologies of thrombosis and type 1 diabetes. Based on an understanding of the molecular mechanisms of these diseases, these efforts will lead to new treatment paradigms and better outcomes for patients.Veralox is developing a disease-modifying therapy for Type 1 diabetes, another immune-driven pathology. In Type 1 diabetes patients, an abn...
We are developing first-in-class small molecule therapeutics that treat the underlying pathologies of thrombosis and type 1 diabetes. Based on an understanding of the molecular mechanisms of these diseases, these efforts will lead to new treatment paradigms and better outcomes for patients.Veralox is developing a disease-modifying therapy for Type 1 diabetes, another immune-driven pathology. In Type 1 diabetes patients, an abnormal immune response results in damage and destruction to insulin-producing pancreatic β-cells. Inflammatory signals increase the expression of 12-LOX, leading to an overabundance of 12-HETE. 12-HETE stresses β-cells
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